Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Birgit Schwanke"'
Autor:
Durga Praveen Meka, Melanie Richter, Tabitha Rücker, Hannah Voss, Anne Rissiek, Christoph Krisp, Nisha Hemandhar Kumar, Birgit Schwanke, Eugenio F. Fornasiero, Hartmut Schlüter, Froylan Calderon de Anda
Publikováno v:
STAR Protocols, Vol 5, Iss 1, Pp 102793- (2024)
Summary: Here, we present a protocol for differential multi-omic analyses of distinct cell types in the developing mouse cerebral cortex. We describe steps for in utero electroporation, subsequent flow-cytometry-based isolation of developing mouse co
Externí odkaz:
https://doaj.org/article/eee56e1f1edb44948be54c5032d54001
Autor:
Vickie Kwan, Durga Praveen Meka, Sean H. White, Claudia L. Hung, Nicholas T. Holzapfel, Susan Walker, Nadeem Murtaza, Brianna K. Unda, Birgit Schwanke, Ryan K.C. Yuen, Kendra Habing, Chloe Milsom, Kristin J. Hope, Ray Truant, Stephen W. Scherer, Froylan Calderon de Anda, Karun K. Singh
Publikováno v:
Cell Reports, Vol 17, Iss 7, Pp 1892-1904 (2016)
The development of neural connectivity is essential for brain function, and disruption of this process is associated with autism spectrum disorders (ASDs). DIX domain containing 1 (DIXDC1) has previously been implicated in neurodevelopmental disorder
Externí odkaz:
https://doaj.org/article/3a5ecf5bb9b64b5cab80d85b37eba2ff
Autor:
Melad Henis, Tabitha Rücker, Robin Scharrenberg, Melanie Richter, Lucas Baltussen, Durga Praveen Meka, Birgit Schwanke, Nagammal Neelagandan, Danie Daaboul, Nadeem Murtaza, Christoph Krisp, Sönke Harder, Hartmut Schlüter, Matthias Kneussel, Irm Hermans-Borgmeyer, Joris de Wit, Karun K. Singh, Kent E. Duncan, Froylan Calderón de Anda
Microdeletions in the 16p11.2 region of the human genome are frequently associated with autism spectrum disorders (ASDs), but how these genomic rearrangements cause ASD remains unclear. Here, we reveal that TAOK2β, a protein isoform encoded by the h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e448c12bfba4de860c37afbe5605911c
https://doi.org/10.1101/2022.08.22.504812
https://doi.org/10.1101/2022.08.22.504812
Autor:
Nadeem Murtaza, Annie A. Cheng, Chad O. Brown, Durga Praveen Meka, Shuai Hong, Jarryll A. Uy, Joelle El-Hajjar, Neta Pipko, Brianna K. Unda, Birgit Schwanke, Sansi Xing, Bhooma Thiruvahindrapuram, Worrawat Engchuan, Brett Trost, Eric Deneault, Froylan Calderon de Anda, Bradley W. Doble, James Ellis, Evdokia Anagnostou, Gary D. Bader, Stephen W. Scherer, Yu Lu, Karun K. Singh
Publikováno v:
Cell reports. 41(8)
There are hundreds of risk genes associated with autism spectrum disorder (ASD), but signaling networks at the protein level remain unexplored. We use neuron-specific proximity-labeling proteomics (BioID2) to identify protein-protein interaction (PPI
Autor:
Robin Scharrenberg, Melanie Richter, Ole Johanns, Durga Praveen Meka, Tabitha Rücker, Nadeem Murtaza, Zsuzsa Lindenmaier, Jacob Ellegood, Anne Naumann, Bing Zhao, Birgit Schwanke, Jan Sedlacik, Jens Fiehler, Ileana L. Hanganu-Opatz, Jason P. Lerch, Karun K. Singh, Froylan Calderon de Anda
Publikováno v:
Molecular psychiatry.
The precise development of the neocortex is a prerequisite for higher cognitive and associative functions. Despite numerous advances that have been made in understanding neuronal differentiation and cortex development, our knowledge regarding the imp
Autor:
Durga Praveen Meka, Oliver Kobler, Shuai Hong, Carina Meta Friedrich, Souhaila Wuesthoff, Melad Henis, Birgit Schwanke, Christoph Krisp, Nessa Schmuelling, René Rueter, Tabitha Ruecker, Ewelina Betleja, Tao Cheng, Moe R. Mahjoub, Peter Soba, Hartmut Schlüter, Eugenio F. Fornasiero, Froylan Calderon de Anda
Publikováno v:
Cell reports, 39(3):110686
Microtubule (MT) modifications are critical during axon development, with stable MTs populating the axon. How these modifications are spatially coordinated is unclear. Here, via high-resolution microscopy, we show that early developing neurons have f
Autor:
T. Ruecker, Oliver Kobler, R. Rueter, Christoph Krisp, N. Schmuelling, Eugenio F. Fornasiero, Hartmut Schlüter, F. Calderon de Anda, Birgit Schwanke, S. Wuesthoff, Durga Praveen Meka
Microtubule remodeling is critical during axon development when the more stable microtubules populate the axon. It is not completely understood, however, how this local cytoskeleton remodeling is coordinated. The centrosome, the main microtubule-orga
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::63206d604d729e63b942cf41c52699f1
https://doi.org/10.1101/2020.12.29.424696
https://doi.org/10.1101/2020.12.29.424696
Autor:
Robin Scharrenberg, Birgit Schwanke, Durga Praveen Meka, Michael R. Kreutz, Oliver Kobler, Sabine Windhorst, Froylan Calderon de Anda, Bing Zhao, Theresa König, Marina Mikhaylova
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-16 (2017)
Scientific Reports
Scientific reports, 7:9583
Scientific Reports
Scientific reports, 7:9583
Neuronal polarization is reflected by different dynamics of microtubule and filamentous actin (F-actin). Axonal microtubules are more stable than those in the remaining neurites, while dynamics of F-actin in axonal growth cones clearly exceed those i
Autor:
Robin Scharrenberg, Michael R. Kreutz, Carlos G. Dotti, Dennis Eggert, Oliver Kobler, Durga Praveen Meka, Froylan Calderon de Anda, Sabine Windhorst, Birgit Schwanke, Sergei Klykov, Melanie Richter, Marina Mikhaylova, Theresa König, Irina Schaefer, Bing Zhao
Publikováno v:
EMBO Reports
EMBO reports, 20(12):e47743
EMBO reports, 20(12):e47743
The centrosome is thought to be the major neuronal microtubule‐organizing center (MTOC) in early neuronal development, producing microtubules with a radial organization. In addition, albeit in vitro, recent work showed that isolated centrosomes cou
Autor:
Oliver Kobler, Marina Mikhaylova, Sabine Windhorst, Durga Praveen Meka, Melanie Richter, Sergei Klykov, Dennis Eggert, Bing Zhao, Birgit Schwanke, Kreutz, Carlos G. Dotti, Froylan Calderon de Anda, Robin Scharrenberg, Irina Schaefer, Theresa König
The centrosome is thought to be the major neuronal microtubule-organizing center (MTOC) in early neuronal development, producing microtubules with a radial organization. In addition, albeit in vitro, recent work showed that isolated centrosomes could
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11e5d91ba059f53322da214c78a06e48