Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Birgit Romberg"'
Publikováno v:
Bioconjugate Chemistry. 18:2131-2136
We prepared thermosensitive poly( N-(2-hydroxypropyl)methacrylamide mono/dilactate) (pHPMA mono/dilactate) polymer and studied temperature-triggered contents release from polymer-coated liposomes. HPMA mono/dilactate polymer was synthesized with a ch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a301f1debf78b29f4c96eff2ac7e5c4e
https://doi.org/10.1021/bc700245p
https://doi.org/10.1021/bc700245p
Publikováno v:
Pharmaceutical Research
Nanoparticles, such as liposomes, polymeric micelles, lipoplexes and polyplexes are frequently studied as targeted drug carrier systems. The ability of these particles to circulate in the bloodstream for a prolonged period of time is often a prerequi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59f5ef7af6890920b40f73838f495357
http://europepmc.org/articles/PMC2190344
http://europepmc.org/articles/PMC2190344
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Biomembranes. 1768(3):737-743
‘Stealth’ liposomes with a poly(ethylene glycol) (PEG) coating are frequently studied for drug delivery and diagnostic purposes because of their prolonged blood circulation kinetics. However, several recent reports have demonstrated that PEG-lipo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58d27601afb50a19202549c3059d3e98
Autor:
Wim E. Hennink, Birgit Romberg, J. Jantina Kettenes‐van den Bosch, Gert Storm, Tom de Vringer
Publikováno v:
Bioconjugate Chemistry. 17:860-864
Liposomes coated with the poly(amino acid) poly(hydroxyethyl-L-asparagine) (PHEA) show long-circulation properties comparable to the frequently used PEG-liposomes. The pharmacokinetic characteristics of long-circulating liposomes are dependent on the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b716637611a2f0aafb7ffce9d96c4747
https://doi.org/10.1021/bc060045a
https://doi.org/10.1021/bc060045a
Autor:
Josbert M. Metselaar, Gert Storm, Birgit Romberg, K. Motonaga, Wim E. Hennink, T. deVringer, J. J. Kettenes-van den Bosch, C. Oussoren
Publikováno v:
Bioconjugate Chemistry. 16:767-774
Liposomes coated with poly(hydroxyethyl L-glutamine) (PHEG) show prolonged circulation times and biodistribution patterns comparable to PEG-coated liposomes. While PEG is a nondegradable polymer, PHEG is expected to be hydrolyzed by proteases. In thi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e37539cc5038eaa20fd3442e261fca67
https://doi.org/10.1021/bc0497719
https://doi.org/10.1021/bc0497719
Publikováno v:
International journal of pharmaceutics. 355(1-2)
The enzymatically degradable poly(amino acid)–lipid conjugate poly(hydroxyethyl l -glutamine)– N -succinyl-dioctadecylamine (PHEG–DODASuc) has been shown to effectively prolong liposome circulation times. In this paper, we investigated whether
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b09f09414b758294ad78a81ea5588797
https://pubmed.ncbi.nlm.nih.gov/18206323
https://pubmed.ncbi.nlm.nih.gov/18206323
Publikováno v:
Pharmaceutical Research
Long-circulating liposomes, such as PEG-liposomes, are frequently studied for drug delivery and diagnostic purposes. In our group, poly(amino acid) (PAA)-based coatings for long-circulating liposomes have been developed. These coatings provide liposo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63abe1ef1c258cc10dab378da8db3769
https://pubmed.ncbi.nlm.nih.gov/17674159
https://pubmed.ncbi.nlm.nih.gov/17674159
Autor:
Spiro Konstantinov, Stanislav Rangelov, Gert Storm, Birgit Romberg, Stanislav Yanev, Denitsa Momekova, Nikolay Lambov, Elena Nikolova
Publikováno v:
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences. 32(4-5)
A major hurdle towards in vivo utilization of pH-sensitive liposomes is their prompt sequestration by reticuloendothelial system and hence short circulation time. Prolonged circulation of liposomes is usually achieved by incorporation of pegylated li
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b4c0e8f07ad7c2d6cd8a96a08804ba9
https://pubmed.ncbi.nlm.nih.gov/17928206
https://pubmed.ncbi.nlm.nih.gov/17928206
Publikováno v:
Pharmaceutical Research; Jan2008, Vol. 25 Issue 1, p55-71, 17p
Publikováno v:
Pharmaceutical Research; Dec2007, Vol. 24 Issue 12, p2394-2401, 8p