Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Birgit Piep"'
Autor:
Nils Kriedemann, Felix Manstein, Carlos A. Hernandez-Bautista, Kevin Ullmann, Wiebke Triebert, Annika Franke, Mira Mertens, Inês Carvalheira Arnaut Pombeiro Stein, Andreas Leffler, Merlin Witte, Tamari Askurava, Veronika Fricke, Ina Gruh, Birgit Piep, Kathrin Kowalski, Theresia Kraft, Robert Zweigerdt
Publikováno v:
Stem Cell Research & Therapy, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Background Commonly used media for the differentiation of human pluripotent stem cells into cardiomyocytes (hPSC-CMs) contain high concentrations of proteins, in particular albumin, which is prone to quality variations and presents a substan
Externí odkaz:
https://doaj.org/article/c071a733e7104321b7fcea2933e63725
Autor:
Valentin Burkart, Kathrin Kowalski, David Aldag-Niebling, Julia Beck, Dirk Alexander Frick, Tim Holler, Ante Radocaj, Birgit Piep, Andre Zeug, Denise Hilfiker-Kleiner, Cristobal G. dos Remedios, Jolanda van der Velden, Judith Montag, Theresia Kraft
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
Transcriptional bursting is a common expression mode for most genes where independent transcription of alleles leads to different ratios of allelic mRNA from cell to cell. Here we investigated burst-like transcription and its consequences in cardiac
Externí odkaz:
https://doaj.org/article/b474c750ea6f47e1a619c482725c63c5
Autor:
Alfredo Jesus López-Dávila, Joseph M. Chalovich, Stefan Zittrich, Birgit Piep, Faramarz Matinmehr, Andras Málnási-Csizmadia, Anna Á. Rauscher, Theresia Kraft, Bernhard Brenner, Robert Stehle
Publikováno v:
Frontiers in Physiology, Vol 11 (2020)
It has been shown that not only calcium but also strong binding myosin heads contribute to thin filament activation in isometrically contracting animal fast-twitch and cardiac muscle preparations. This behavior has not been studied in human muscle fi
Externí odkaz:
https://doaj.org/article/44a2581e2ee844f2b914999690386b9e
Autor:
Bogdan Iorga, Kristin Schwanke, Natalie Weber, Meike Wendland, Stephan Greten, Birgit Piep, Cristobal G. dos Remedios, Ulrich Martin, Robert Zweigerdt, Theresia Kraft, Bernhard Brenner
Publikováno v:
Frontiers in Physiology, Vol 8 (2018)
Characterizing the contractile function of human pluripotent stem cell-derived cardiomyocytes (hPSC-CMs) is key for advancing their utility for cellular disease models, promoting cell based heart repair, or developing novel pharmacological interventi
Externí odkaz:
https://doaj.org/article/2141cbe2b4944298869c2089b299ca9a
Autor:
Natalie Weber, Kathrin Kowalski, Tim Holler, Ante Radocaj, Martin Fischer, Stefan Thiemann, Jeanne de la Roche, Kristin Schwanke, Birgit Piep, Neele Peschel, Uwe Krumm, Alexander Lingk, Meike Wendland, Stephan Greten, Jan Dieter Schmitto, Issam Ismail, Gregor Warnecke, Urs Zywietz, Boris Chichkov, Joachim Meißner, Axel Haverich, Ulrich Martin, Bernhard Brenner, Robert Zweigerdt, Theresia Kraft
Publikováno v:
Stem Cell Reports
Summary Human pluripotent stem cell-derived cardiomyocytes (hPSC-CMs) represent an attractive model to investigate CM function and disease mechanisms. One characteristic marker of ventricular specificity of human CMs is expression of the ventricular,
Autor:
Robert Stehle, Faramarz Matinmehr, Alfredo Jesus López-Dávila, András Málnási-Csizmadia, Bernhard Brenner, Stefan Zittrich, Joseph M. Chalovich, Theresia Kraft, Anna Á. Rauscher, Birgit Piep
Publikováno v:
Frontiers in Physiology, Vol 11 (2020)
Frontiers in Physiology
Frontiers in Physiology
It has been shown that not only calcium but also strong binding myosin heads contribute to thin filament activation in isometrically contracting animal fast-twitch and cardiac muscle preparations. This behavior has not been studied in human muscle fi
Autor:
Felix Osten, Natalie Weber, Bogdan Iorga, Meike Wendland, Tim Holler, Santoshi Biswanath, Alea K. Bodenschatz, Birgit Piep, Simon Kröhn, Jana Teske, Annika Franke, Robert Zweigerdt, Joachim D. Meiβner, Theresia Kraft
Publikováno v:
Biophysical Journal. 121:381a
Autor:
Judith Montag, Theresia Kraft, Britta Keyser, David Aldag-Niebling, J. van der Velden, C.G. dos Remedios, Valentin Burkart, Julia Beck, D Hilfigker-Kleiner, Birgit Piep
Publikováno v:
European Heart Journal. 40
Hypertrophic cardiomyopathy (HCM) is mostly caused by mutations in sarcomeric proteins. About 90% of mutation-positive patients have mutations in one of four proteins: the β-myosin heavy chain (β-MyHC, MYH7), cardiac myosin binding protein C (cMyBP
Autor:
Jan Nicolas Riesselmann, Annika Franke, Kathrin Kowalski, Theresia Kraft, Robert Zweigerdt, Natalie Weber, Ulrich Martin, Birgit Piep
Publikováno v:
Biophysical Journal. 120:136a
Autor:
Natalie Weber, Tim Holler, Joachim Meißner, Judith Montag, Martin Fischer, Jeanne de la Roche, Stefan Thiemann, Neele Peschel, Anne Kathrin Mayer, Kristin Schwanke, Birgit Piep, Ulrich Martin, Robert Zweigerdt, Theresia Kraft
Publikováno v:
Biophysical Journal. 118:257a