Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Birgit Korioth-Schmitz"'
Autor:
Manjunatha M Venkataswamy, Tony W Ng, Shalu S Kharkwal, Leandro J Carreño, Alison J Johnson, Shajo Kunnath-Velayudhan, Zheng Liu, Robert Bittman, Peter J Jervis, Liam R Cox, Gurdyal S Besra, Xiangshu Wen, Weiming Yuan, Moriya Tsuji, Xiangming Li, David D Ho, John Chan, Sunhee Lee, Richard Frothingham, Barton F Haynes, Michael W Panas, Geoffrey O Gillard, Jaimie D Sixsmith, Birgit Korioth-Schmitz, Joern E Schmitz, Michelle H Larsen, William R Jacobs, Steven A Porcelli
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e108383 (2014)
Recombinant Mycobacterium bovis bacillus Calmette-Guèrin (rBCG) has been explored as a vector for vaccines against HIV because of its ability to induce long lasting humoral and cell mediated immune responses. To maximize the potential for rBCG vacci
Externí odkaz:
https://doaj.org/article/90e45a31ded54c5cbca2c3231d0f0e54
Autor:
Stefan Barth, Jörn Engelbert Schmitz, Karinna Chouman, Markus Sack, Birgit Korioth-Schmitz, Torsten Klockenbring, Rainer Fischer, Anh Tuan Pham, Rolf Fendel
Publikováno v:
European Cytokine Network. 29:59-72
Interleukin-6 (IL-6) expression and secretion, induced by inflammatory processes, stimulate the acute phase response cascade. The overexpression of IL-6 contributes to a variety of inflammatory diseases, e.g. rheumatoid arthritis, Castleman's disease
Autor:
Casey C. Perley, Richard Frothingham, Norman L. Letvin, Eva M. Click, Birgit Korioth-Schmitz, Sunhee Lee, Jaimie D. Sixsmith
Publikováno v:
Vaccine. 33(42):5715-5722
Background A recombinant Mycobacterium bovis BCG (rBCG) vector expressing HIV transgenes is an attractive candidate as a dual vaccine against HIV and TB. However, pre-existing immune responses to mycobacteria may influence immune responses to rBCG. W
Autor:
Dieter Affeln, Birgit Korioth-Schmitz, Michael Wong, Gary B. Schweon, Susanne L. Simon, Adrian Gardner, William M. Decaneas
Publikováno v:
Applied Biosafety. 20:6-11
The vaccinia virus vaccine was effectively used during the 19th and 20th centuries to eradicate smallpox. Over the last decade, vaccinia virus and derived recombinant vectors have been increasingly...
Autor:
Kathleen McGee, Hassan Javanbakht, Birgit Korioth-Schmitz, Nicole Espy, Joseph Sodroski, Norman L. Letvin, Hillel Haim
Publikováno v:
Journal of Virology. 88:21-40
Envelope glycoprotein (Env) reactivity (ER) describes the propensity of human immunodeficiency virus type 1 (HIV-1) Env to change conformation from the metastable unliganded state in response to the binding of ligands (antibodies and soluble CD4 [sCD
Autor:
Randi Gombos, Sandrine L. Hulot, Yi Zheng, Joshua Owuor, Birgit Korioth-Schmitz, Michelle A. Lifton, Norman L. Letvin, Christian Ayeni, Dror Kolodkin-Gal, Mohammed Asmal, Wendy W. Yeh, Robert M. Najarian, Gideon Zamir
Publikováno v:
Journal of Virology. 87:13589-13597
Effective strategies are needed to block mucosal transmission of human immunodeficiency virus type 1 (HIV-1). Here, we address a crucial question in HIV-1 pathogenesis: whether infected donor mononuclear cells or cell-free virus plays the more import
Autor:
Roland Zahn, Ming Li, David C. Montefiori, Harikrishnan Balachandran, Robert B. White, Birgit Korioth-Schmitz, Norman L. Letvin, Vanessa M. Hirsch, Sarah Pryputniewicz, Melisa D. Rett, Amitinder Kaur, Haili Tang, Jonathan S. Allan, Jörn E. Schmitz, Angela Carville
Publikováno v:
Blood. 115:3070-3078
One of the most puzzling observations in HIV research is the lack of pathogenicity in most nonhuman primate species that are natural hosts of simian immunodeficiency virus (SIV) infection. Despite this, natural hosts experience a level of viremia sim
Autor:
Angela Carville, Kevin R. Carlson, Birgit Korioth-Schmitz, Norman L. Letvin, Harikrishnan Balachandran, Barton F. Haynes, Mark Cayabyab, Yue Sun, Adam P. Buzby, William R. Jacobs, Ayako Miura
Publikováno v:
Journal of Virology. 83:5505-5513
While mycobacteria have been proposed as vaccine vectors because of their persistence and safety, little has been done systematically to optimize their immunogenicity in nonhuman primates. We successfully generated recombinant Mycobacterium bovis BCG
Autor:
Charles R. Brown, Adam P. Buzby, Russell Byrum, Simoy Goldstein, Jörn E. Schmitz, Vanessa M. Hirsch, Roland Zahn, Gordon J. Freeman, Melisa D. Rett, Norman L. Letvin, Yue Sun, Birgit Korioth-Schmitz
Publikováno v:
Journal of Virology. 82:11577-11588
African green monkeys (AGM) do not develop overt signs of disease following simian immunodeficiency virus (SIV) infection. While it is still unknown how natural hosts like AGM can cope with this lentivirus infection, a large number of investigations
Autor:
Victor Yoon, Keith G. Mansfield, Liljana Stevceva, Mark C. Poznansky, Michael Santosuosso, Beatriz Pacheco, Angela Carville, Birgit Korioth-Schmitz
Publikováno v:
The Journal of Immunology. 181:5510-5521
Gp120 is a critical component of the envelope of HIV-1. Its role in viral entry is well described. In view of its position on the viral envelope, gp120 is a part of the retrovirus that immune cells encounter first and has the potential to influence a