Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Birgit Kühnapfel"'
Autor:
Angelique Renzaho, Jürgen Podlech, Birgit Kühnapfel, Franziska Blaum, Matthias J. Reddehase, Niels A. W. Lemmermann
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 10 (2020)
Reactivation of latent cytomegalovirus (CMV) in recipients of hematopoietic cell transplantation (HCT) not only results in severe organ manifestations, but can also cause “graft failure” resulting in bone marrow (BM) aplasia. This inhibition of h
Externí odkaz:
https://doaj.org/article/621eefee74214383b1a86bc512f6242c
Autor:
Niels A. W. Lemmermann, Birgit Kühnapfel, Angélique Renzaho, Julia K Schmiedeke, Christof K. Seckert, Marion Griessl
Publikováno v:
Medical Microbiology and Immunology. 208:439-446
Roizman's definition of herpesviral latency, which applies also to cytomegaloviruses (CMVs), demands maintenance of reactivation-competent viral genomes after clearance of productive infection. It is more recent understanding that failure to complete
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::784f32d046801fbd087deb285157631b
https://doi.org/10.1007/s00430-019-00615-8
https://doi.org/10.1007/s00430-019-00615-8
Autor:
Franziska Blaum, Niels A. W. Lemmermann, Matthias J. Reddehase, Angélique Renzaho, Jürgen Podlech, Birgit Kühnapfel
Publikováno v:
Frontiers in Cellular and Infection Microbiology
Frontiers in Cellular and Infection Microbiology, Vol 10 (2020)
Frontiers in Cellular and Infection Microbiology, Vol 10 (2020)
Reactivation of latent cytomegalovirus (CMV) in recipients of hematopoietic cell transplantation (HCT) not only results in severe organ manifestations, but can also cause "graft failure" resulting in bone marrow (BM) aplasia. This inhibition of hemat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ad93bd5d5302f8d2ea1a74113d132b4
https://doi.org/10.3389/fcimb.2020.00138
https://doi.org/10.3389/fcimb.2020.00138
Autor:
Jürgen Podlech, Annette Fink, Kai A. Kropp, Matthias J. Reddehase, Birgit Kühnapfel, Natascha K. A. Grzimek, Angélique Renzaho, Christian O. Simon
Publikováno v:
Journal of General Virology. 90:2395-2401
Major immediate-early (MIE) transcriptional enhancers of cytomegaloviruses are key regulators that are regarded as determinants of virus replicative fitness and pathogenicity. The MIE locus of murine cytomegalovirus (mCMV) shows bidirectional gene-pa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd4389ac485e37f56597956ad946e459
https://doi.org/10.1099/vir.0.012245-0
https://doi.org/10.1099/vir.0.012245-0
Publikováno v:
Journal of Virology. 81:7805-7810
Enhancers are defined as DNA elements that increase transcription when placed in any orientation relative to a promoter. The major immediate-early (MIE) enhancer region of murine cytomegalovirus is flanked by transcription units ie1/3 and ie2 , which
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c01b8eae40c60ddd33bbc9376c841a32
https://doi.org/10.1128/jvi.02388-06
https://doi.org/10.1128/jvi.02388-06
Autor:
Christian O. Simon, Silke A. Oehrlein-Karpi, Dennis Strand, Torsten Däubner, Rafaela Holtappels, Hanna-Mari Tervo, Verena Böhm, Natascha K. A. Grzimek, Angélique Renzaho, Matthias J. Reddehase, Jürgen Podlech, Birgit Kühnapfel
Publikováno v:
Journal of Virology. 80:10436-10456
During murine cytomegalovirus (mCMV) latency in the lungs, most of the viral genomes are transcriptionally silent at the major immediate-early locus, but rare and stochastic episodes of desilencing lead to the expression of IE1 transcripts. This low-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::002a3fd0d2657d86919bf11558be05f4
https://doi.org/10.1128/jvi.01248-06
https://doi.org/10.1128/jvi.01248-06
Autor:
Petra Deegen, Christof K. Seckert, Matthias J. Reddehase, Claudia Krause, Hanna-Mari Tervo, Angélique Renzaho, Natascha K. A. Grzimek, Birgit Kühnapfel
Latent cytomegalovirus (CMV) is frequently transmitted by organ transplantation, and its reactivation under conditions of immunosuppressive prophylaxis against graft rejection by host-versus-graft disease bears a risk of graft failure due to viral pa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c7ead03de1be108d812c6a1124e6f69
https://europepmc.org/articles/PMC2738169/
https://europepmc.org/articles/PMC2738169/
Autor:
Jürgen Podlech, Rafaela Holtappels, Torsten Däubner, Simone F. Emde, Natascha K. A. Grzimek, Ann B. Hill, Doris Thomas, Silke A. Oehrlein-Karpi, Matthias J. Reddehase, Birgit Kühnapfel, Petra Deegen, Christian O. Simon, Michael W. Munks
Cytomegalovirus (CMV) infection continues to be a complication in recipients of hematopoietic stem cell transplantation (HSCT). Preexisting donor immunity is recognized as a favorable prognostic factor for the reconstitution of protective antiviral i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b191ba10aab04b512f27ea2f4eb2e04
https://europepmc.org/articles/PMC2395166/
https://europepmc.org/articles/PMC2395166/