Newly constructed stable reporter cell lines for mechanistic studies on electrophile-responsive element-mediated gene expression reveal a role for flavonoid planarity

Autor: Jac M.M.J.G. Aarts, Yee Y. Lee-Hilz, Hester van der Woude, Ellen Kampman, Ivonne M.C.M. Rietjens, Martijn Vermeulen, Anne-Marie J. F. Boerboom, Birgit I. Bremer, Peter J. van Bladeren

Publikováno v: Biochemical Pharmacology, 2, 72, 217-226
Biochemical Pharmacology, 72, 217-26
Biochemical Pharmacology, 72(2), 217-226
Biochemical Pharmacology, 72, 2, pp. 217-26
Biochemical Pharmacology 72 (2006) 2

The electrophile-responsive element (EpRE) is a transcriptional enhancer involved in cancer-chemoprotective gene expression modulation by certain food components. Two stably transfected luciferase reporter cell lines were developed, EpRE(hNQO1)-LUX a

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