Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Birgit Gassner"'
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 8, Iss 2, Pp 143-152 (2006)
The expression and activity of P-glycoprotein (pGP) play a role in the multidrug resistance of tumors. Because solid-growing tumors often show pronounced hypoxia or extracellular acidosis, this study attempted to analyze the impact of an acidic envir
Externí odkaz:
https://doaj.org/article/51e497e4120445659aedbfae0bd70747
Autor:
Monique Losekoot, Thomas Premsler, Jan M. Wit, Birgit Gassner, Claudia A. L. Ruivenkamp, Ruey-Bing Yang, Gijs W. E. Santen, Sabine E. Hannema, Wilma Oostdijk, Ferdinand Roelfsema, Thomas D. Mueller, Alberto M. Pereira, Heike Oberwinkler, André G. Uitterlinden, Sarina G. Kant, Hermine A. van Duyvenvoorde, Eric A. Espiner, Timothy C. R. Prickett, Michaela Kuhn, Annemieke J.M.H. Verkerk
Publikováno v:
Journal of Clinical Endocrinology and Metabolism, 98(12), E1988-E1998
Journal of Clinical Endocrinology and Metabolism, 98(12), E1988-E1998. The Endocrine Society
Journal of Clinical Endocrinology and Metabolism, 98(12), E1988-E1998. Endocrine Society
Hannema, S E, Van Duyvenvoorde, H A, Thomas, P, Yang, R B, Mueller, T D, Gassner, B, Oberwinkler, H, Roelfsema, F, Santen, G W E, Prickett, T, Kant, S G, Verkerk, A J M H, Uitterlinden, A G, Espiner, E, Ruivenkamp, C A L, Oostdijk, W, Pereira, A M, Losekoot, M, Kuhn, M & Wit, J M 2013, ' An activating mutation in the kinase homology domain of the natriuretic peptide receptor-2 causes extremely tall stature without skeletal deformities ', Journal of Clinical Endocrinology and Metabolism, vol. 98, no. 12, pp. E1988-E1998 . https://doi.org/10.1210/jc.2013-2358
Journal of Clinical Endocrinology and Metabolism, 98(12), E1988-E1998. The Endocrine Society
Journal of Clinical Endocrinology and Metabolism, 98(12), E1988-E1998. Endocrine Society
Hannema, S E, Van Duyvenvoorde, H A, Thomas, P, Yang, R B, Mueller, T D, Gassner, B, Oberwinkler, H, Roelfsema, F, Santen, G W E, Prickett, T, Kant, S G, Verkerk, A J M H, Uitterlinden, A G, Espiner, E, Ruivenkamp, C A L, Oostdijk, W, Pereira, A M, Losekoot, M, Kuhn, M & Wit, J M 2013, ' An activating mutation in the kinase homology domain of the natriuretic peptide receptor-2 causes extremely tall stature without skeletal deformities ', Journal of Clinical Endocrinology and Metabolism, vol. 98, no. 12, pp. E1988-E1998 . https://doi.org/10.1210/jc.2013-2358
Background: C-type natriuretic peptide (CNP)/natriuretic peptide receptor 2 (NPR2) signaling is essential for long bone growth. Enhanced CNP production caused by chromosomal translocations results in tall stature, a Marfanoid phenotype, and skeletal
Autor:
Ralph T. Schermuly, Kai Schuh, Michaela Kuhn, Marco Abeßer, Hideo A. Baba, Bhola K. Dahal, Baktybek Kojonazarov, Katharina Völker, Franziska Werner, Birgit Gaßner
Publikováno v:
Basic Research in Cardiology
The cardiac hormone atrial natriuretic peptide (ANP) regulates systemic and pulmonary arterial blood pressure by activation of its cyclic GMP-producing guanylyl cyclase-A (GC-A) receptor. In the lung, these hypotensive effects were mainly attributed
Autor:
Ruth H. Strasser, Wen Chen, Jens Waschke, Viacheslav O. Nikolaev, Birgit Gaßner, Nadine Steinbronn, Nicolas Schlegel, Sebastian Börner, Michaela Kuhn
Publikováno v:
Cardiovascular Research
Aims Cardiac atrial natriuretic peptide (ANP) participates in the maintenance of arterial blood pressure and intravascular volume homeostasis. The hypovolaemic effects of ANP result from coordinated actions in the kidney and systemic microcirculation
Autor:
Laura Marroquí, Michaela Kuhn, Sergi Soriano, Angel Nadal, Noèlia Téllez, Eduard Montanya, Ivan Quesada, Birgit Gassner, Ana B. Ropero, Eva Tudurí, Pablo Juan-Picó
Publikováno v:
Dipòsit Digital de la UB
Universidad de Barcelona
Recercat. Dipósit de la Recerca de Catalunya
instname
Universidad de Barcelona
Recercat. Dipósit de la Recerca de Catalunya
instname
Atrial natriuretic peptide (ANP) and its guanylyl cyclase-A (GC-A) receptor are being involved in metabolism, although their role in the endocrine pancreas is still greatly unknown. The aim of this work is to study a possible role for the ANP/GC-A sy
Autor:
Michaela Kuhn, Alexandra Gazinski, René P. Zahedi, Jens Waschke, Albert Sickmann, Michael Hartmann, Juliane Schröter, Birgit Gaßner
Publikováno v:
FEBS Journal. 277:2440-2453
Atrial natriuretic peptide (ANP), via its guanylyl cyclase A (GC-A) receptor and intracellular guanosine 3′,5′-cyclic monophosphate production, is critically involved in the regulation of blood pressure. In patients with chronic heart failure, th
Autor:
Yueh Chen Lin, Helge Wiig, Tine V. Karlsen, Frits Thorsen, Roger H. Adamson, Fitz Roy E Curry, Olav Tenstad, Michaela Kuhn, Ingrid Moen, Rolf K. Reed, Birgit Gassner, Cecilie Brekke Rygh, Joyce F. Clark
Publikováno v:
The Journal of Physiology. 588:325-339
Atrial natriuretic peptide (ANP) via its guanylyl cyclase-A (GC-A) receptor participates in regulation of arterial blood pressure and vascular volume. Previous studies demonstrated that concerted renal diuretic/natriuretic and endothelial permeabilit
Autor:
Ivan Quesada, Michaela Kuhn, Cristina Ripoll, Birgit Gassner, Angel Nadal, Paloma Alonso-Magdalena, Sergi Soriano, Ana B. Ropero, Jan-Åke Gustafsson
Publikováno v:
Molecular Endocrinology. 23:1973-1982
The ATP-sensitive potassium (K(ATP)) channel is a key molecule involved in glucose-stimulated insulin secretion. The activity of this channel regulates beta-cell membrane potential, glucose- induced [Ca(2+)](i) signals, and insulin release. In this s
Autor:
Michael Hartmann, Michaela Kuhn, Birgit Gassner, Viacheslav O. Nikolaev, Juliane Schröter, Moritz Bünemann, Alexandra Gazinski, Boris V. Skryabin, Thomas Müller
Publikováno v:
Journal of Biological Chemistry. 283:28313-28320
Atrial (ANP) and B-type natriuretic peptides (BNP) modulate blood pressure and volume through the stimulation of cyclic GMP production by their guanylyl cyclase-A (GC-A) receptor. A novel isoform of GC-A has been identified that is the result of diff
Publikováno v:
Endocrinology. 148:4162-4169
The cardiac hormones atrial and brain natriuretic peptides (NPs) counteract the systemic, hypertensive, and hypervolemic actions of angiotensin II (Ang II) via their guanylyl cyclase-A (GC-A) receptor. In the present study, we took advantage of genet