Zobrazeno 1 - 10
of 100
pro vyhledávání: '"Birgit, Knoechel"'
Autor:
Julia Frede, Julia Poller, Kayleen Shi, Hannah Stuart, Noori Sotoudeh, Klothilda Lim, Caroline Wiggers, Johannes Waldschmidt, Valeriya Dimitrova, Anna Montanaro, Eugene Cho, Tushara Vijaykumar, Paul Richardson, Nikhil Munshi, Kenneth Anderson, Nathan Martin, Shari Kaiser, Marc-Steffen Raab, Birgit Knoechel, Jens Lohr
Publikováno v:
HemaSphere, Vol 7, p e04864bb (2023)
Externí odkaz:
https://doaj.org/article/37887b7d013c49af82780d0224567747
Autor:
Valeriya Dimitrova, Julia Frede, Anna Montanaro, Sayalee Potdar, Hannah Stuart, Noori Sotoudeh, Alexandria Van Scoyk, Shruti Bhatt, Anthony Letai, Jon Aster, Jens Lohr, Birgit Knoechel
Publikováno v:
HemaSphere, Vol 7, p e0988081 (2023)
Externí odkaz:
https://doaj.org/article/459025a526d14fc299d00b0cd99cda76
Autor:
Anna Montanaro, Samuel Kitara, Elisa Cerretani, Matteo Marchesini, Chiara Rompietti, Luca Pagliaro, Andrea Gherli, Angela Su, Maria Laura Minchillo, Mariafrancesca Caputi, Rodanthi Fioretzaki, Bruno Lorusso, Linda Ross, Gabriela Alexe, Elena Masselli, Marina Marozzi, Federica Maria Angela Rizzi, Roberta La Starza, Cristina Mecucci, Yan Xiong, Jian Jin, Angela Falco, Birgit Knoechel, Franco Aversa, Olivia Candini, Federico Quaini, Paolo Sportoletti, Kimberly Stegmaier, Giovanni Roti
Publikováno v:
Cell Death and Disease, Vol 13, Iss 6, Pp 1-14 (2022)
Abstract Genomic studies have identified recurrent somatic alterations in genes involved in DNA methylation and post-translational histone modifications in acute lymphoblastic leukemia (ALL), suggesting new opportunities for therapeutic interventions
Externí odkaz:
https://doaj.org/article/58958922e64b41ed9d4be8309e2d65c4
Autor:
Kavitha Ramaswamy, Lauren Forbes, Gerard Minuesa, Tatyana Gindin, Fiona Brown, Michael G. Kharas, Andrei V. Krivtsov, Scott A. Armstrong, Eric Still, Elisa de Stanchina, Birgit Knoechel, Richard Koche, Alex Kentsis
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
MYB activity is a key factor for the maintenance of acute myeloid leukemias but it is also a difficult target. Here, the authors develop a peptidomimetic (MYBMIM) that prevents the interaction of the trans-activation domain of MYB with the KIX domain
Externí odkaz:
https://doaj.org/article/a470abd9ea4643cfb47136bbe875cfb7
Autor:
Birgit Knoechel, Jens G. Lohr, Clemens Grassberger, Michal R. Schweiger, Jordan Voisine, Leili Niu, Noori Sotudeh, Johannes M. Waldschmidt, Sarah K. Stegmann, Praveen Anand, Jing Yang, Claire C. Havig, Julia Frede, Anna J. Rogers, Megha Wal, Amy Guillaumet-Adkins, Nam Gyu Im
Supplementary Figure from Regulatory Programs of B-cell Activation and Germinal Center Reaction Allow B-ALL Escape from CD19 CAR T-cell Therapy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1461ffae81e455480dbc104159552524
https://doi.org/10.1158/2326-6066.22545521
https://doi.org/10.1158/2326-6066.22545521
Autor:
Birgit Knoechel, Jens G. Lohr, Clemens Grassberger, Michal R. Schweiger, Jordan Voisine, Leili Niu, Noori Sotudeh, Johannes M. Waldschmidt, Sarah K. Stegmann, Praveen Anand, Jing Yang, Claire C. Havig, Julia Frede, Anna J. Rogers, Megha Wal, Amy Guillaumet-Adkins, Nam Gyu Im
Supplementary Data from Regulatory Programs of B-cell Activation and Germinal Center Reaction Allow B-ALL Escape from CD19 CAR T-cell Therapy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a1cab44d8dd5b83fb0303dc28d6bb43
https://doi.org/10.1158/2326-6066.22545545.v1
https://doi.org/10.1158/2326-6066.22545545.v1
Autor:
Birgit Knoechel, Jens G. Lohr, Clemens Grassberger, Michal R. Schweiger, Jordan Voisine, Leili Niu, Noori Sotudeh, Johannes M. Waldschmidt, Sarah K. Stegmann, Praveen Anand, Jing Yang, Claire C. Havig, Julia Frede, Anna J. Rogers, Megha Wal, Amy Guillaumet-Adkins, Nam Gyu Im
Chimeric antigen receptor (CAR) T-cell therapy has led to tremendous successes in the treatment of B-cell malignancies. However, a large fraction of treated patients relapse, often with disease expressing reduced levels of the target antigen. Here, w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::013cb78acd001d1f3f5016652d1d6251
https://doi.org/10.1158/2326-6066.c.6550964
https://doi.org/10.1158/2326-6066.c.6550964
Autor:
Sriram Sathyanarayanan, Jon C. Aster, X. Shirley Liu, Warren S. Pear, Bradley E. Bernstein, Birgit Knoechel, Brandon E. Kremer, Theresa Zhang, Gary Gilliland, Stephen Fawell, Leigh Zawel, Christopher Moskaluk, Brian B. Haines, Jason Laskey, Michael Kluk, Philip W. Garrett-Engele, John MacLean, Chris Ware, Jing Yuan, Chongzhi Zang, Hongfang Wang, Li Pan, Andrew Truong, Serguei Lejnine, Alexander Stoeck
human Breast tumor Notch gene coverage annotations.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::772c70e0961cfb13b051a4fed2d019a3
https://doi.org/10.1158/2159-8290.22529885.v1
https://doi.org/10.1158/2159-8290.22529885.v1
Autor:
Sriram Sathyanarayanan, Jon C. Aster, X. Shirley Liu, Warren S. Pear, Bradley E. Bernstein, Birgit Knoechel, Brandon E. Kremer, Theresa Zhang, Gary Gilliland, Stephen Fawell, Leigh Zawel, Christopher Moskaluk, Brian B. Haines, Jason Laskey, Michael Kluk, Philip W. Garrett-Engele, John MacLean, Chris Ware, Jing Yuan, Chongzhi Zang, Hongfang Wang, Li Pan, Andrew Truong, Serguei Lejnine, Alexander Stoeck
S1: NOTCH gene rearrangement in breast cancer cell lines and human breast tumors. S2: NOTCH gene rearrangement and sensitivity to MRK-003. S3: HES4 expression is associated with NOTCH gene-rearrangement or activating mutation in NOTCH. S4: HES4 expre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba7e587c75653d144fc20a17c000c13a
https://doi.org/10.1158/2159-8290.22529894.v1
https://doi.org/10.1158/2159-8290.22529894.v1
Autor:
Sriram Sathyanarayanan, Jon C. Aster, X. Shirley Liu, Warren S. Pear, Bradley E. Bernstein, Birgit Knoechel, Brandon E. Kremer, Theresa Zhang, Gary Gilliland, Stephen Fawell, Leigh Zawel, Christopher Moskaluk, Brian B. Haines, Jason Laskey, Michael Kluk, Philip W. Garrett-Engele, John MacLean, Chris Ware, Jing Yuan, Chongzhi Zang, Hongfang Wang, Li Pan, Andrew Truong, Serguei Lejnine, Alexander Stoeck
File includes genomic analysis, cell cycle and cell proliferation analysis.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be61200c03fe3c0610304a985d3928e9
https://doi.org/10.1158/2159-8290.22529891.v1
https://doi.org/10.1158/2159-8290.22529891.v1