Zobrazeno 1 - 10
of 58
pro vyhledávání: '"Birgit, Hotz"'
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 12, Iss 10, Pp 797-806 (2010)
PURPOSE: Tumor endothelial cells express vascular endothelial growth factor receptor 2 (VEGFR-2). VEGF can direct toxins to tumor vessels through VEGFR-2 for antiangiogenic therapy. This study aimed to selectively damage the VEGFR-2-overexpressing va
Externí odkaz:
https://doaj.org/article/a10a9919a55b4d41b3dd2ba45facab90
Publikováno v:
International Journal of Colorectal Disease. 29:1339-1348
The taurine derivative taurolidine (TRD) exerts anti-neoplastic effects in a variety of tumor models. On the other hand, TRD at low doses was shown to reduce cell-cell adhesion, a prerequisite for metastasis. The aim of this study was to elucidate th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfad962ebfbce1d561094f0170089a49
https://doi.org/10.1007/s00384-014-1998-4
https://doi.org/10.1007/s00384-014-1998-4
Autor:
Hans-Juergen Raatschen, Birgit Hotz, Heinz J. Buhr, Hubert G. Hotz, Christian-Olaf Schoenfeld, Benjamin Zsivcsec, Susanne Fischer
Publikováno v:
Acta Radiologica. 55:131-139
Background Currently, early changes of tumor vasculature after angiogenesis inhibition can only be evaluated by histopathology, a method not suitable in a clinical setting. Purpose To quantify effects of different angiogenesis inhibitors on the micro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79150a29d5d2c1314a0c45507592877f
https://doi.org/10.1177/0284185113493776
https://doi.org/10.1177/0284185113493776
Autor:
Jörg C. Hoffmann, Andrea Stroux, Birgit Hotz, Anja A. Kühl, Bernd Frericks, Steffi Valdeig, Bernd Misselwitz, Christoph Loddenkemper, Frank Wacker
Publikováno v:
Investigative Radiology. 46:478-485
To determine the colonic mural enhancement in a rat model of inflammatory bowel disease (IBD) using gadofluorine M- and diethylenetriamine pentaacetic acid (Gd-DTPA)-enhanced magnetic resonance (MR) imaging, and to correlate the degree of enhancement
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fba1db1e201588234f2f9e92c1dea368
https://doi.org/10.1097/rli.0b013e31821459ff
https://doi.org/10.1097/rli.0b013e31821459ff
Publikováno v:
Anti-Cancer Agents in Medicinal Chemistry. 11:448-454
Epithelial to mesenchymal transition (EMT) is a biological process that allows well-differentiated, polarized epithelial cells to undergo a conversion to motile, unpolarized mesenchymal cells. EMT plays crucial roles during implantation, embryogenesi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7da550225eff68d846e1b1b4fa1b613f
https://doi.org/10.2174/187152011795677436
https://doi.org/10.2174/187152011795677436
Publikováno v:
Langenbeck's Archives of Surgery. 396:535-541
Surgical therapy remains the only curative option for pancreatic ductal adenocarcinoma. But even after complete resection, almost all patients suffer from local tumor recurrence. Current standard adjuvant therapy with gemcitabine does not impressivel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6919d405dc7ce7215af1a45238cbe28
https://doi.org/10.1007/s00423-011-0770-2
https://doi.org/10.1007/s00423-011-0770-2
Autor:
Vanessa Al-Rawi, Martin Augsten, Thorsten Läufer, Oliver Coutelle, Birgit Hotz, Yvonne Heneka, Alexandra Matzke-Ogi
Publikováno v:
Cancer Research. 78:3960-3960
Introduction: In cancer patients, the development of metastases is associated with a poor clinical prognosis. Metastatic dissemination requires cancer cells to detach from the primary tumor and invade adjacent or distant tissue. This process involves
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::57878ac063e6a2f07ea64caae4d7eb9d
https://doi.org/10.1158/1538-7445.am2018-3960
https://doi.org/10.1158/1538-7445.am2018-3960
Publikováno v:
Journal of Gastrointestinal Surgery. 14:388-397
Snail, a transcription factor linked to epithelial to mesenchymal transition (EMT) during embryonic development and tumor progression, is associated with migration of cells. During inflammation and tissue injury, cell movement is also observed to pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9db2792f7d694710df4f878a7b48072f
https://doi.org/10.1007/s11605-009-1068-3
https://doi.org/10.1007/s11605-009-1068-3
Autor:
Anja A. Kühl, Christoph Loddenkemper, Birgit Hotz, Bernd Misselwitz, Steffi Valdeig, Bernd Frericks, Karl-Jürgen Wolf, Frank Wacker, Jörg C. Hoffmann
Publikováno v:
Investigative Radiology. 44:23-30
OBJECTIVES To quantitatively and qualitatively characterize the MR findings of inflammatory bowel disease in a rat model after i.v. injection of the reticuloendothelial system cell specific ultrasmall iron oxide SHU 555 C. MATERIALS AND METHODS Colit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c569b0816bbc2256228b839d6b34b1b
https://doi.org/10.1097/rli.0b013e3181899025
https://doi.org/10.1097/rli.0b013e3181899025
Publikováno v:
Journal of Gastrointestinal Surgery. 12:900-906
We investigated the effect of suramin on tumor growth and spread in an immunocompetent, orthotopic rat model of pancreatic cancer and analyzed the tumor vasculature by intravital microscopy.In vitro, rat ductal pancreatic cancer cells (DSL-6A) were i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67a5e4ae1a566096a5c687f92329600c
https://doi.org/10.1007/s11605-008-0507-x
https://doi.org/10.1007/s11605-008-0507-x