Zobrazeno 1 - 10
of 1 158
pro vyhledávání: '"Birger Lindberg"'
Autor:
Victor Forman, Dan Luo, Fernando Geu-Flores, René Lemcke, David R. Nelson, Sotirios C. Kampranis, Dan Staerk, Birger Lindberg Møller, Irini Pateraki
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
Although ginkgo terpenoids have been studied extensively for their pharmaceutical properties, knowledge on their biosynthesis remains limited. Here, the authors identify five multifunctional cytochrome P450s that catalyze the generation of the tert-b
Externí odkaz:
https://doaj.org/article/625d23f8b7ba4ad3881949143a0e2ccc
Autor:
Nikolaj Lervad Hansen, Louise Kjaerulff, Quinn Kalby Heck, Victor Forman, Dan Staerk, Birger Lindberg Møller, Johan Andersen-Ranberg
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)
How triptonide is made in the medicinal plant Tripterygium wilfordii is largely unknown. Here, the authors report the identification and characterization of a suite of cytochrome P450s and show their function in catalyzing the formation of triptonide
Externí odkaz:
https://doaj.org/article/aefc7279e2034fbc9995e5406ec82039
Autor:
Simon Bo Jensen, Sara Thodberg, Shaheena Parween, Matias E. Moses, Cecilie C. Hansen, Johannes Thomsen, Magnus B. Sletfjerding, Camilla Knudsen, Rita Del Giudice, Philip M. Lund, Patricia R. Castaño, Yanet G. Bustamante, Maria Natalia Rojas Velazquez, Flemming Steen Jørgensen, Amit V. Pandey, Tomas Laursen, Birger Lindberg Møller, Nikos S. Hatzakis
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
P450 oxidoreductase (POR) selectively activates numerous cytochromes P450 (CYP), crucial for metabolism of drugs, steroids and xenobiotics and natural product biosynthesis. Here, the authors identify ligands that bind POR and bias its specificity tow
Externí odkaz:
https://doaj.org/article/ecd3eccafadb4f149283420e2e8e2cea
Autor:
Oliver Gericke, Nikolaj Lervad Hansen, Gustav Blichfeldt Pedersen, Louise Kjaerulff, Dan Luo, Dan Staerk, Birger Lindberg Møller, Irini Pateraki, Allison Maree Heskes
Publikováno v:
BMC Plant Biology, Vol 20, Iss 1, Pp 1-15 (2020)
Abstract Background Eremophila R.Br. (Scrophulariaceae) is a diverse genus of plants with species distributed across semi-arid and arid Australia. It is an ecologically important genus that also holds cultural significance for many Indigenous Austral
Externí odkaz:
https://doaj.org/article/d5a00cea6f1f48f2a5da14729942c466
Autor:
Marcus Ehlert, Lea Møller Jagd, Ilka Braumann, Christoph Dockter, Christoph Crocoll, Mohammed Saddik Motawia, Birger Lindberg Møller, Michael Foged Lyngkjær
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-10 (2019)
Abstract Barley (Hordeum vulgare L.) produces five leucine-derived hydroxynitrile glucosides, potentially involved in alleviating pathogen and environmental stresses. These compounds include the cyanogenic glucoside epiheterodendrin. The biosynthetic
Externí odkaz:
https://doaj.org/article/175be527fd484e239b15709ad90f0624
Autor:
Moon Young Ryu, Seok Keun Cho, Yourae Hong, Jinho Kim, Jong Hum Kim, Gu Min Kim, Yan-Jun Chen, Eva Knoch, Birger Lindberg Møller, Woo Taek Kim, Michael Foged Lyngkjær, Seong Wook Yang
Publikováno v:
BMC Genomics, Vol 20, Iss 1, Pp 1-15 (2019)
Abstract Background Controlled turnover of proteins as mediated by the ubiquitin proteasome system (UPS) is an important element in plant defense against environmental and pathogen stresses. E3 ligases play a central role in subjecting proteins to hy
Externí odkaz:
https://doaj.org/article/da799c351d28475681f100b947c731ff
Publikováno v:
Microbial Cell Factories, Vol 17, Iss 1, Pp 1-17 (2018)
Abstract Background Forskolin is a high-value diterpenoid produced exclusively by the Lamiaceae plant Coleus forskohlii. Today forskolin is used pharmaceutically for its adenyl-cyclase activating properties. The limited availability of pure forskolin
Externí odkaz:
https://doaj.org/article/69a23d5b1ef74282be1ea89c7930d33d
Biosynthesis of cyanogenic glucosides in Phaseolus lunatus and the evolution of oxime‐based defenses
Autor:
Daniela Lai, Alexandra B. Maimann, Eliana Macea, César H. Ocampo, Gustavo Cardona, Martina Pičmanová, Behrooz Darbani, Carl Erik Olsen, Daniel Debouck, Bodo Raatz, Birger Lindberg Møller, Fred Rook
Publikováno v:
Plant Direct, Vol 4, Iss 8, Pp n/a-n/a (2020)
Abstract Lima bean, Phaseolus lunatus, is a crop legume that produces the cyanogenic glucosides linamarin and lotaustralin. In the legumes Lotus japonicus and Trifolium repens, the biosynthesis of these two α‐hydroxynitrile glucosides involves cyt
Externí odkaz:
https://doaj.org/article/b98f17926da34db7b24e2ad6419b66c8
Publikováno v:
Frontiers in Plant Science, Vol 10 (2019)
Sorghum bicolor (L.) Moench produces the nitrogen-containing natural product dhurrin that provides chemical defense against herbivores and pathogens via the release of toxic hydrogen cyanide gas. Drought can increase dhurrin in shoot tissues to conce
Externí odkaz:
https://doaj.org/article/ae86f82db04a450da60bc8a43f24725c
Autor:
Krutika Bavishi, Darui Li, Stine Eiersholt, Emma N. Hooley, Troels C. Petersen, Birger Lindberg Møller, Nikos S. Hatzakis, Tomas Laursen
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-9 (2018)
Abstract Cytochrome P450 oxidoreductase (POR) is the primary electron donor in eukaryotic cytochrome P450 (CYP) containing systems. A wealth of ensemble biophysical studies of Cytochrome P450 oxidoreductase (POR) has reported a binary model of the co
Externí odkaz:
https://doaj.org/article/8fa4bf61be47432a9c951c289cdc90d1