The translational challenge in the development of new and effective therapies for endometriosis: a review of confidence from published preclinical efficacy studies.

Autor: Pullen N, Birch CL, Douglas GJ, Hussain Q, Pruimboom-Brees I, Walley RJ

Publikováno v: Human Reproduction Update; Nov2011, Vol. 17 Issue 6, p791-802, 12p

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

DOCKopathies: A systematic review of the clinical pathologies associated with human DOCK pathogenic variants.

Autor: Samani A; Department of Pediatrics, Division of Neurology at the University of Alabama at Birmingham and Children's of Alabama, Birmingham, Alabama, USA., English KG; Department of Pediatrics, Division of Neurology at the University of Alabama at Birmingham and Children's of Alabama, Birmingham, Alabama, USA., Lopez MA; Department of Pediatrics, Division of Neurology at the University of Alabama at Birmingham and Children's of Alabama, Birmingham, Alabama, USA., Birch CL; Department of Pediatrics, Division of Pediatric Hematology and Oncology at the University of Alabama at Birmingham and Children's of Alabama, Birmingham, Alabama, USA.; Center for Computational Genomics and Data Science at Children's of Alabama, Birmingham, Alabama, USA., Brown DM; Department of Pediatrics, Division of Pediatric Hematology and Oncology at the University of Alabama at Birmingham and Children's of Alabama, Birmingham, Alabama, USA.; Center for Computational Genomics and Data Science at Children's of Alabama, Birmingham, Alabama, USA., Kaur G; Department of Pediatrics, Division of Pediatric Hematology and Oncology at the University of Alabama at Birmingham and Children's of Alabama, Birmingham, Alabama, USA.; Center for Computational Genomics and Data Science at Children's of Alabama, Birmingham, Alabama, USA., Worthey EA; Department of Pediatrics, Division of Pediatric Hematology and Oncology at the University of Alabama at Birmingham and Children's of Alabama, Birmingham, Alabama, USA.; Center for Computational Genomics and Data Science at Children's of Alabama, Birmingham, Alabama, USA., Alexander MS; Department of Pediatrics, Division of Neurology at the University of Alabama at Birmingham and Children's of Alabama, Birmingham, Alabama, USA.; UAB Center for Exercise Medicine at the University of Alabama at Birmingham, Birmingham, Alabama, USA.; Department of Genetics at the University of Alabama at Birmingham, Birmingham, Alabama, USA.; UAB Civitan International Research Center (CIRC), at the University of Alabama at Birmingham, Birmingham, Alabama, USA.; UAB Center for Neurodegeneration and Experimental Therapeutics (CNET), Birmingham, Alabama, USA.

Publikováno v: Human mutation [Hum Mutat] 2022 Sep; Vol. 43 (9), pp. 1149-1161. Date of Electronic Publication: 2022 May 20.

VarSight: prioritizing clinically reported variants with binary classification algorithms.

Autor: Holt JM; HudsonAlpha Institute for Biotechnology, Software Development and Informatics, 601 Genome Way, Huntsville, 35806, USA. jholt@hudsonalpha.org., Wilk B; HudsonAlpha Institute for Biotechnology, Software Development and Informatics, 601 Genome Way, Huntsville, 35806, USA., Birch CL; HudsonAlpha Institute for Biotechnology, Software Development and Informatics, 601 Genome Way, Huntsville, 35806, USA., Brown DM; HudsonAlpha Institute for Biotechnology, Software Development and Informatics, 601 Genome Way, Huntsville, 35806, USA., Gajapathy M; HudsonAlpha Institute for Biotechnology, Software Development and Informatics, 601 Genome Way, Huntsville, 35806, USA., Moss AC; HudsonAlpha Institute for Biotechnology, Software Development and Informatics, 601 Genome Way, Huntsville, 35806, USA., Sosonkina N; HudsonAlpha Institute for Biotechnology, Software Development and Informatics, 601 Genome Way, Huntsville, 35806, USA.; University of Alabama at Birmingham, Department of Genetics, 720 20th Street South, Birmingham, 35294, USA., Wilk MA; HudsonAlpha Institute for Biotechnology, Software Development and Informatics, 601 Genome Way, Huntsville, 35806, USA., Anderson JA; HudsonAlpha Institute for Biotechnology, Software Development and Informatics, 601 Genome Way, Huntsville, 35806, USA., Harris JM; HudsonAlpha Institute for Biotechnology, Software Development and Informatics, 601 Genome Way, Huntsville, 35806, USA., Kelly JM; HudsonAlpha Institute for Biotechnology, Software Development and Informatics, 601 Genome Way, Huntsville, 35806, USA., Shaterferdosian F; HudsonAlpha Institute for Biotechnology, Software Development and Informatics, 601 Genome Way, Huntsville, 35806, USA., Uno-Antonison AE; HudsonAlpha Institute for Biotechnology, Software Development and Informatics, 601 Genome Way, Huntsville, 35806, USA., Weborg A; HudsonAlpha Institute for Biotechnology, Software Development and Informatics, 601 Genome Way, Huntsville, 35806, USA., Worthey EA; HudsonAlpha Institute for Biotechnology, Software Development and Informatics, 601 Genome Way, Huntsville, 35806, USA.

Publikováno v: BMC bioinformatics [BMC Bioinformatics] 2019 Oct 15; Vol. 20 (1), pp. 496. Date of Electronic Publication: 2019 Oct 15.

LKB1/Mo25/STRAD uniquely impacts sarcomeric contractile function and posttranslational modification.

Autor: Behunin SM; Sarver Molecular Cardiovascular Research Program, Department of Physiology, University of Arizona, Tucson, Arizona., Lopez-Pier MA; Sarver Molecular Cardiovascular Research Program, Department of Physiology, University of Arizona, Tucson, Arizona., Birch CL; Sarver Molecular Cardiovascular Research Program, Department of Physiology, University of Arizona, Tucson, Arizona., McKee LAK; Sarver Molecular Cardiovascular Research Program, Department of Physiology, University of Arizona, Tucson, Arizona., Danilo C; Sarver Molecular Cardiovascular Research Program, Department of Physiology, University of Arizona, Tucson, Arizona., Khalpey Z; Department of Surgery, University of Arizona, Tucson, Arizona., Konhilas JP; Sarver Molecular Cardiovascular Research Program, Department of Physiology, University of Arizona, Tucson, Arizona. Electronic address: konhilas@arizona.edu.

Publikováno v: Biophysical journal [Biophys J] 2015 Mar 24; Vol. 108 (6), pp. 1484-1494.