Zobrazeno 1 - 10
of 69
pro vyhledávání: '"Birajalaxmi Das"'
Autor:
Vinay Jain, Divyalakshmi Saini, D. C. Soren, V. Anil Kumar, P. R. Vivek Kumar, P. K. M. Koya, G. Jaikrishan, Birajalaxmi Das
Publikováno v:
Genes and Environment, Vol 45, Iss 1, Pp 1-11 (2023)
Abstract Background The human population living in high level natural radiation areas (HLNRAs) of Kerala coast provide unique opportunities to study the biological effects of low dose and low dose rate ionizing radiation below 100 mGy. The level of r
Externí odkaz:
https://doaj.org/article/9fb4b7f971114e7da82de2649953b49c
Autor:
K. R. Sudheer, P. K. Mohammad Koya, Anu J. Prakash, Ambily M. Prakash, R. Manoj Kumar, S. Shyni, C. K. Jagadeesan, G. Jaikrishan, Birajalaxmi Das
Publikováno v:
Genes and Environment, Vol 44, Iss 1, Pp 1-10 (2022)
Abstract Background The human population residing in monazite bearing Kerala coast are exposed to chronic low dose and low dose rate external gamma radiation due to Th232 deposits in its beach sand. The radiation level in this area varies from 1.50 m
Externí odkaz:
https://doaj.org/article/184a9e771c364ea5a5a3f41e3f850a4d
Autor:
Shridevi Shelke, Birajalaxmi Das
Publikováno v:
Genes and Environment, Vol 43, Iss 1, Pp 1-16 (2021)
Abstract Background Radio-adaptive response (RAR) is transient phenomena, where cells conditioned with a small dose (priming) of ionizing radiation shows significantly reduced DNA damage with a subsequent high challenging dose. The role of DNA double
Externí odkaz:
https://doaj.org/article/cc8d57a01c7c4ab6b640acaeacac09a5
Autor:
Vinay Jain, Birajalaxmi Das
Publikováno v:
PLoS ONE, Vol 12, Iss 11, p e0187274 (2017)
The high level natural radiation areas (HLNRA) of Kerala coast in south west India is unique for its wide variation in the background radiation dose (15.0 mGy/year] to find out differentially expressed genes and their biological significance in respo
Externí odkaz:
https://doaj.org/article/1d103b5e4b9548169ae32436ffe54408
Publikováno v:
PLoS ONE, Vol 4, Iss 12, p e8440 (2009)
BACKGROUND:Telomere length is considered as a biomarker of aging, stress, cancer. It has been associated with many chronic diseases such as hypertension and diabetes. Although, telomere shortening due to ionizing radiation has been reported in vitro,
Externí odkaz:
https://doaj.org/article/f0a91b7bd40a4b57ab6d560e4de513aa
Autor:
Birajalaxmi Das, Rashmi Priya
Publikováno v:
Molecular and Cellular Biochemistry. 477:267-281
DNA methylation is an epigenetic mechanism, which plays an important role in gene regulation. The present study evaluated DNA methylation profile of LINE1 repeats and promoter methylation of DNA damage response (DDR) and DNA repair (DR) genes (PARP1,
Publikováno v:
Mutation research. 825
The high level natural radiation areas (HLNRA) of Kerala coast provide unique opportunity to study the biological effect of chronic low dose ionizing radiation (LDIR) on human population below 100 mSv. The radiation level in this area varies from 1.0
Autor:
Sneh M. Toprani, Birajalaxmi Das
Publikováno v:
Environmental and Molecular Mutagenesis. 61:551-559
Radio-adaptive response (RAR) is a biological mechanism, where cells primed with a low dose exhibit reduced DNA damage with a high challenging dose. Single nucleotide polymorphisms (SNPs) of DNA repair genes including base excision repair (BER) pathw
Autor:
Vinay Jain, Birajalaxmi Das, P.R. Vivek Kumar, Divyalakshmi Saini, D C Soren, G. Jaikrishan, K. R. Sudheer, P. K. M. Koya
Publikováno v:
International Journal of Radiation Biology. 96:734-739
Background: Single Nucleotide Polymorphisms (SNPs) at DNA repair genes are considered as potential biomarkers of radio-sensitivity. The coastal belt of Kerala in south west India has a patchy distr...
Autor:
Rashmi, Priya, Birajalaxmi, Das
Publikováno v:
Molecular and cellular biochemistry. 477(1)
DNA methylation is an epigenetic mechanism, which plays an important role in gene regulation. The present study evaluated DNA methylation profile of LINE1 repeats and promoter methylation of DNA damage response (DDR) and DNA repair (DR) genes (PARP1,