Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Biplob Mitra"'
Autor:
Sonal V. Bhujbal, Biplob Mitra, Uday Jain, Yuchuan Gong, Anjali Agrawal, Shyam Karki, Lynne S. Taylor, Sumit Kumar, Qi (Tony) Zhou
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 11, Iss 8, Pp 2505-2536 (2021)
Amorphous solid dispersions (ASDs) are popular for enhancing the solubility and bioavailability of poorly water-soluble drugs. Various approaches have been employed to produce ASDs and novel techniques are emerging. This review provides an updated ov
Externí odkaz:
https://doaj.org/article/0afe3c36ee094777a4ffc9e235011077
Publikováno v:
Journal of Pharmaceutical Sciences. 111:710-716
The increase in solid fraction (SF) of a packed granule bed with pressure applied during the in-die compression process results in an evolution of the tablet's matrix and mechanical strength. In this case study, the tensile strength (TS) of a dry gra
Autor:
Qi Tony Zhou, Yuchuan Gong, Lynne S. Taylor, Biplob Mitra, Shyam Karki, Uday Jain, Sumit Kumar, Anjali Agrawal, Sonal V Bhujbal
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 11, Iss 8, Pp 2505-2536 (2021)
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica. B
Amorphous solid dispersions (ASDs) are popular for enhancing the solubility and bioavailability of poorly water-soluble drugs. Various approaches have been employed to produce ASDs and novel techniques are emerging. This review provides an updated ov
Autor:
Daniel Schaufelberger, Asha Rajapakshe, Stephen W. Hoag, Matthew Santangelo, Jing Liu, Ramesh Sood, Trupti Dixit, Steven Mount, Erica Radden, Karen C. Thompson, Mona Khurana, Shailly Mehrotra, Jian Wang, Biplob Mitra, Jamzad Shahla, Sandra Klein, John J. Alexander, Maren Kuhli, Robert Louis Ternik, Jennifer Walsh, Arzu Selen, Yuet Mei Khong, Elizabeth Galella, Stuart Charlton, David Cheng Thiam Tan, Elimika Pfuma Fletcher
Publikováno v:
European Journal of Pharmaceutics and Biopharmaceutics. 164:54-65
A workshop on "Pediatric Formulation Development: Challenges of Today and Strategies for Tomorrow" was organized jointly by the University of Maryland's Center of Excellence in Regulatory Science and Innovation (M-CERSI), the U.S. Food and Drug Admin
Autor:
Yuchuan Gong, Biplob Mitra, Saikishore Meruva, Sumit Kumar, William Bowen, Prajwal Thool, Shyam Karki, Anjali Agrawal
Publikováno v:
Journal of pharmaceutical sciences. 110(9)
Developing solid oral drug products with good content uniformity (CU) at low doses is challenging; this challenge further aggravates when the tablet size decreases from a conventional tablet to a micro/mini-tablet (1.2–3 mm diameter). To alleviate
Autor:
Prajwal Thool, Shyam Karki, Anjali Agrawal, Jhalak Patel, Jianmin Li, William Bowen, Saikishore Meruva, Biplob Mitra, Shashwat Gupta
Publikováno v:
International journal of pharmaceutics. 587
Low dose micro-tablets with acceptable quality attributes, specifically content uniformity (CU), would not only enhance the dose flexibility in the clinic, but also decrease excipient burden in pediatric population. Considering the CU challenges asso
Autor:
Jessica Chang, Michael C. Victor, Thomas Z. Gunter, Sy-Juen Wu, Biplob Mitra, Robert Louis Ternik, Chad Nolan Wolfe
Publikováno v:
International Journal of Pharmaceutics. 525:149-159
Mini-tablets have potential applications as a flexible drug delivery tool in addition to their generally perceived use as multi-particulates. That is, mini-tablets could provide flexibility in dose finding studies and/or allow for combination therapi
Autor:
Phenil J. Patel, Christopher Breslin, Michael Koenig, Aaron Zettler, Jon Hilden, Aktham Aburub, Allgeier Matthew Carl, Biplob Mitra
Publikováno v:
Journal of Pharmaceutical Innovation. 11:189-199
In pharmaceutical development, powder flow characteristics are notoriously difficult to predict. Although tests exist that aim to determine the flowability of powders, many have not been definitively correlated with a powder’s performance in downst
Publikováno v:
Powder Technology. 291:328-336
To improve the understanding of how dry granulation and in particular, granule solid fraction (SF) impact the compaction behavior of plastically deformable microcrystalline cellulose (MCC), in this study, the Drucker Prager Cap (DPC) model parameters
Publikováno v:
Powder Technology. 291:487-498
Calibration of the Drucker Prager Cap (DPC) model parameters provides a means for a deeper understanding of the impact of granule composition on the compaction properties of dry granules independent of their solid fraction. In this study, monodispers