Zobrazeno 1 - 10
of 124
pro vyhledávání: '"Biplab Dasgupta"'
Autor:
Daniel Shiloh Malawsky, Taylor Dismuke, Hedi Liu, Ethan Castellino, Jay Brenman, Biplab Dasgupta, Andrey Tikunov, Timothy R. Gershon
Publikováno v:
iScience, Vol 26, Iss 12, Pp 108443- (2023)
Summary: We show that inactivating AMPK in a genetic medulloblastoma model depletes tumor stem cells and slows progression. In medulloblastoma, the most common malignant pediatric brain tumor, drug-resistant stem cells co-exist with transit-amplifyin
Externí odkaz:
https://doaj.org/article/ce27806c9aa3458681f0983682896568
Autor:
Aniruddha S. Karve, Janki M. Desai, Sidharth N. Gadgil, Nimita Dave, Trisha M. Wise-Draper, Gary A. Gudelsky, Timothy N. Phoenix, Biplab DasGupta, Lalanthica Yogendran, Soma Sengupta, David R. Plas, Pankaj B. Desai
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 6, p 3217 (2024)
A glioblastoma (GBM) is one of the most aggressive, infiltrative, and treatment-resistant malignancies of the central nervous system (CNS). The current standard of care for GBMs include maximally safe tumor resection, followed by concurrent adjuvant
Externí odkaz:
https://doaj.org/article/d0a4c09af4b5404385800fc2b3d6571b
Publikováno v:
STAR Protocols, Vol 2, Iss 1, Pp 100375- (2021)
Summary: Reactive astrogliosis is characterized by a profound change in astrocyte phenotype in response to all CNS injuries. Here, we present a revised in situ hybridization and immunohistochemistry (IHC) protocol to label the reactive astrocytes in
Externí odkaz:
https://doaj.org/article/ad1f1c487d9449a9b2ece30d1f55ce4d
Insight on Transcriptional Regulation of the Energy Sensing AMPK and Biosynthetic mTOR Pathway Genes
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
The Adenosine Monophosphate-activated Protein Kinase (AMPK) and the Mechanistic Target of Rapamycin (mTOR) are two evolutionarily conserved kinases that together regulate nearly every aspect of cellular and systemic metabolism. These two kinases sens
Externí odkaz:
https://doaj.org/article/810092ee6feb4b07800d8a44a2299445
Autor:
Biplab Dasgupta
In this comprehensive appraisal of Indian economic reforms, the author recounts how reforms were initiated and how they unfolded in stages since 1991. He analyzes all the components of the structural adjustment programme including in the agrarian, in
PDF file - 589K, Figure S1. Antiproliferative effects of Compound C in glioma cells. Figure S2. Compound C induces AMPK-independent autophagy and the antiproliferative effects of Compound C are not blocked by autophagy and apoptosis inhibitors. Figur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51829fc4b4046e084da24df4b1efb731
https://doi.org/10.1158/1535-7163.22500571
https://doi.org/10.1158/1535-7163.22500571
AMP-activated protein kinase (AMPK) is an evolutionarily conserved energy sensor important for cell growth, proliferation, survival, and metabolic regulation. Active AMPK inhibits biosynthetic enzymes like mTOR and acetyl CoA carboxylase (required fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f24e4838be782a18ebf43d579f475da
https://doi.org/10.1158/1535-7163.c.6536500.v1
https://doi.org/10.1158/1535-7163.c.6536500.v1
Autor:
Biplab Dasgupta, Pradip K. Ghosh, Giovanni M. Pauletti, Ashish Kumar, Jason P Clark, Jayeeta Roychoudhury, Nicholas Nassar, Anjelika Gasilina, Heather Henry, Xiaona Liu, Jane Anderson, Rishi Raj Chhipa, Swagata Karkare
PDF file - 71K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a347c8df0152464a950675df42afcb0
https://doi.org/10.1158/1078-0432.22448981
https://doi.org/10.1158/1078-0432.22448981
Autor:
Biplab Dasgupta, Pradip K. Ghosh, Giovanni M. Pauletti, Ashish Kumar, Jason P Clark, Jayeeta Roychoudhury, Nicholas Nassar, Anjelika Gasilina, Heather Henry, Xiaona Liu, Jane Anderson, Rishi Raj Chhipa, Swagata Karkare
Purpose: Classical pharmacology allows the use and development of conventional phytomedicine faster and more economically than conventional drugs. This approach should be tested for their efficacy in terms of complementarity and disease control. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5bb05d83e7a76dac7cf68f33e185eec0
https://doi.org/10.1158/1078-0432.c.6521528
https://doi.org/10.1158/1078-0432.c.6521528
Autor:
Ichiro Nakano, Lyse A. Norian, Burt Nabors, L. James Lee, Mitsutoshi Nakada, Biplab DasGupta, Evan W. Newell, Xinghua Lu, Dolores Hambardzumyan, Sung-Hak Kim, Jun Wang, Svetlana Komarova, Hebaallah Alsheikh, Shinobu Yamaguchi, Soniya Bastola, Suojun Zhang, Hemragul Sabit, Takuya Furuta, Yannick Simoni, Songjian Lu, Zhihong Chen, Rishi Chhipa, Junfeng Shi, Hai Yu, Mutsuko Minata, Justin T. Gibson, Kyung-Don Kang, Hirokazu Sadahiro
Supplementary Figure S3. PROS1 is located in GSCs.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::573ca18e30217544490b554a28a83f69
https://doi.org/10.1158/0008-5472.22416537.v1
https://doi.org/10.1158/0008-5472.22416537.v1