Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Bipin Mistry"'
Autor:
Sihem Ait‐Oudhia, David Jaworowicz, Ziheng Hu, Sébastien Bihorel, Shuai Hu, Budda Balasubrahmanyam, Bipin Mistry, Janethe deOliveira Pena, Larissa Wenning, Ferdous Gheyas
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology, Vol 13, Iss 8, Pp 1380-1393 (2024)
Abstract Sotatercept is a breakthrough, first‐in‐class biologic, that is FDA‐approved for the treatment of pulmonary arterial hypertension (PAH). A population pharmacokinetic (PopPK) model was developed using data from two phase 1 studies in he
Externí odkaz:
https://doaj.org/article/07f11222d7fe402eaf9609211402a6c2
Autor:
Kevin A. Schulman, Bipin Mistry, Robert S. Kaplan, Brent C. James, Arnold Milstein, M.C. Mazza, M. Kalani, R. Mann, V.G. Narayanan, J. Xue, Terry Platchek, C. Pinnock, J. Punnen, G. Poulsen, Christine Nguyen, Feryal Erhun, Michael J. Mack, D. Shetty, D. Ballard, K. Brayton, Dhruv S. Kazi
Publikováno v:
American Heart Journal
Background Multiple modern Indian hospitals operate at very low cost while meeting US-equivalent quality accreditation standards. Though US hospitals face intensifying pressure to lower their cost, including proposals to extend Medicare payment rates
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a6ff749f86fbd95dba2b352d01d77eb
Autor:
Gary L. Gottlieb, Robert S. Kaplan, Claire Pierre, Fernet Leandre, Jean Claude Mugunga, Jonathan Warsh, Bipin Mistry, Peterson Abnis I Faure, Anna P Fang, Gregory Jerome, Joseph Rhatigan, Mahek A. Shah, Ryan McBain, Micaela Browning
Publikováno v:
Bulletin of the World Health Organization
To evaluate the implementation of a time-driven activity-based costing analysis at five community health facilities in Haiti.Together with stakeholders, the project team decided that health-care providers should enter start and end times of the patie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a097e8c58d0732b7a3eb025b09257ed
http://europepmc.org/articles/PMC5791872
http://europepmc.org/articles/PMC5791872
Autor:
Robert S. Kaplan, Stephen Hardy, Mary Shannon Fracchia, Bipin Mistry, Joseph Vadakekalam, Jordan A. Garcia, Christopher J. Hartnick, Cheryl Hersh, Carissa Wentland
Publikováno v:
The Laryngoscope. 127:2152-2158
Objectives/Hypothesis Providing high-value healthcare to patients is increasingly becoming an objective for providers including those at multidisciplinary aerodigestive centers. Measuring value has two components: 1) identify relevant health outcomes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6dfc32e765be169129cc3c04aa0d586d
https://doi.org/10.1002/lary.26354
https://doi.org/10.1002/lary.26354
Autor:
Nicola Cresti, Marie Foegh, Mark Matijevic, Divyanshu Dua, Peter Stephens, Yvette Drew, Pallavi Sachdev, Sharon McGonigle, Ruth Plummer, Debashis Sarker, Nancy Hall, Steen Knudsen, Vaishali Dixit, Shannon McGrath, Bipin Mistry
Publikováno v:
British Journal of Cancer
BackgroundThis phase 1 study examined the safety, maximum-tolerated dose (MTD) and antitumour activity of E7449, a novel PARP 1/2 and tankyrase 1/2 inhibitor.MethodsE7449 was orally administered once daily in 28-day cycles to patients with advanced s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c229e23eeddc49ee113a9af76c5a8fdd
https://pubmed.ncbi.nlm.nih.gov/32523090
https://pubmed.ncbi.nlm.nih.gov/32523090
Publikováno v:
The AAPS Journal. 18:1144-1158
The attention and interest in establishing in vivo/in vitro correlations (IVIVCs) is grounded in its tremendous utility as a prognostic tool. It can be used to support formulation optimization, predict in vivo drug exposure across a potential patient
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7820d6c28234d73fbfc4101d202da41
https://doi.org/10.1208/s12248-016-9930-1
https://doi.org/10.1208/s12248-016-9930-1
Autor:
Ravikanth Kona, James E. Polli, Bipin Mistry, Thomas Dowling, Viera Lukacova, Stephen W. Hoag, Raafat Fahmy, Marilyn N. Martinez
Publikováno v:
The AAPS Journal. 18:886-897
This study explored the utility of mechanistic absorption models to describe the in vivo performance of a low solubility/low permeability compound in normal healthy subjects. Sixteen healthy human volunteers received three oral formulations and an in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b6254de1403c3b84e55ee1c140c52ea
https://doi.org/10.1208/s12248-016-9913-2
https://doi.org/10.1208/s12248-016-9913-2
Publikováno v:
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 141
Oral bioavailability of poorly water soluble (BCS II) drugs like danazol can be minimal without the necessary formulation strategies. Availability of in vitro physicochemical and in vivo pharmacokinetic studies can be valuable when designing these st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff4756f41349bab85c7f54651bbdcb86
https://pubmed.ncbi.nlm.nih.gov/31150808
https://pubmed.ncbi.nlm.nih.gov/31150808
Autor:
Edgar Schuck, Christopher Rowbottom, Camilo Rojas, Greg Delahanty, Barbara Slusher, Dana Ferraris, Bipin Mistry, Jesse Alt, Sanjeev Redkar, Bridget Duvall, Kristen Sanders, Takashi Tsukamoto, Kuan-Chun Huang
Publikováno v:
Journal of Medicinal Chemistry. 57:2582-2588
Several 2'-fluorinated tetrahydrouridine derivatives were synthesized as inhibitors of cytidine deaminase (CDA). (4R)-2'-Deoxy-2',2'-difluoro-3,4,5,6-tetrahydrouridine (7a) showed enhanced acid stability over tetrahydrouridine (THU) 5 at its N-glycos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37774bf3f3512e3ee4b578687b2a33fe
https://doi.org/10.1021/jm401856k
https://doi.org/10.1021/jm401856k
The case describes the application of time-driven activity-based costing (TDABC) at a new tertiary hospital operated by Partners-in-Health in Mirebelais, Haiti. A project team mapped the clinical processes for use in estimating the direct costs of pe