Zobrazeno 1 - 10
of 389
pro vyhledávání: '"Biosynthetic techniques"'
Autor:
George C.T. Yeoh, David L. Vaux, Paul G Ekert, James E Vince, Joanne H. van Vuuren, Megan Finch-Edmondson, Bernard A. Callus, Katharine J. Goodall, Ian E Gentle
Publikováno v:
PLoS ONE, Vol 11, Iss 11, p e0164003 (2016)
PLoS ONE
PLoS ONE
Apoptosis mediated by Bax or Bak is usually thought to be triggered by BH3-only members of the Bcl-2 protein family. BH3-only proteins can directly bind to and activate Bax or Bak, or indirectly activate them by binding to anti-apoptotic Bcl-2 family
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6c6cc591fdc88f2734d87e3bff47b7d
Autor:
Burcu Ayhan-Sahin, Zeynep-Elif Apaydın, Pınar Obakan-Yerlikaya, Elif-Damla Arisan, Ajda Coker-Gurkan
Publikováno v:
PLoS ONE
PLoS ONE, Vol 17, Iss 1, p e0260144 (2022)
PLoS ONE, Vol 17, Iss 1 (2022)
PLoS ONE, Vol 17, Iss 1, p e0260144 (2022)
PLoS ONE, Vol 17, Iss 1 (2022)
Background Growth Hormone Releasing Hormone (GHRH), 44 amino acids containing hypothalamic hormone, retains the biological activity by its first 29 amino acids. GHRH (NH2 1–29) peptide antagonists inhibit the growth of prostate, breast, ovarian, re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a6e41bcd29fa1db774d50a036acc648
http://europepmc.org/articles/PMC8782341
http://europepmc.org/articles/PMC8782341
Autor:
Jamie-Lee M. Thompson, Daniel W. D. West, Thomas M. Doering, Boris P. Budiono, Sarah J. Lessard, Lauren G. Koch, Steven L. Britton, Nuala M. Byrne, Matthew A. Brown, Kevin J. Ashton, Vernon G. Coffey
Publikováno v:
PLoS ONE
PLoS ONE, Vol 17, Iss 1, p e0261723 (2022)
PLoS ONE, Vol 17, Iss 1, p e0261723 (2022)
Skeletal muscle atrophy is a physiological response to disuse, aging, and disease. We compared changes in muscle mass and the transcriptome profile after short-term immobilization in a divergent model of high and low responders to endurance training
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc5e361b7e2362fe8ef9b231e30463e1
http://europepmc.org/articles/PMC8757917
http://europepmc.org/articles/PMC8757917
Publikováno v:
PLoS Genetics, Vol 17, Iss 12, p e1009958 (2021)
PLoS Genetics
PLoS Genetics
Cell competition is a context-dependent cell elimination via cell-cell interaction whereby unfit cells (‘losers’) are eliminated from the tissue when confronted with fitter cells (‘winners’). Despite extensive studies, the mechanism that driv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f52357bf372ee49a8772c6f42b233a4
https://doaj.org/article/3b3e2d954b104c4695a3dc42366b29e1
https://doaj.org/article/3b3e2d954b104c4695a3dc42366b29e1
Autor:
Wuguo Deng, Han Yang, Dingbo Shi, Marc R. Gartenberg, Miao Chen, Changlin Zhang, Melinda S. Borrie, Qian Long, Haohui Sun
Publikováno v:
PLoS Genetics
PLoS Genetics, Vol 17, Iss 11, p e1009899 (2021)
PLoS Genetics, Vol 17, Iss 11, p e1009899 (2021)
The robust proliferation of cancer cells requires vastly elevated levels of protein synthesis, which relies on a steady supply of aminoacylated tRNAs. Delivery of tRNAs to the cytoplasm is a highly regulated process, but the machinery for tRNA nuclea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::246416a3eb681e79056604fc3ee954d8
http://europepmc.org/articles/PMC8639082
http://europepmc.org/articles/PMC8639082
Autor:
Upinder S. Bhalla
Publikováno v:
PLoS Computational Biology, Vol 17, Iss 11, p e1009621 (2021)
PLoS Computational Biology
PLoS Computational Biology
Signaling networks mediate many aspects of cellular function. The conventional, mechanistically motivated approach to modeling such networks is through mass-action chemistry, which maps directly to biological entities and facilitates experimental tes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79c380e9d31fed46e4c3927ce8efe4a8
https://doaj.org/article/4b42a275bb2b4cfdadd45c93678bac3a
https://doaj.org/article/4b42a275bb2b4cfdadd45c93678bac3a
Autor:
Andreas Schoen, Jana-Christin Demper, Paul Klemm, Nadine Biedenkopf, Simone Bach, Marcus Lechner, Friedemann Weber, Roland K. Hartmann, Stephan Becker, Lennart Kämper, Julia Schlereth
Publikováno v:
PLoS Pathogens, Vol 17, Iss 10 (2021)
PLoS Pathogens, Vol 17, Iss 10, p e1010002 (2021)
PLoS Pathogens
PLoS Pathogens, Vol 17, Iss 10, p e1010002 (2021)
PLoS Pathogens
Transcription of non-segmented negative sense (NNS) RNA viruses follows a stop-start mechanism and is thought to be initiated at the genome’s very 3’-end. The synthesis of short abortive leader transcripts (leaderRNAs) has been linked to transcri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::464bdc57e40a1f94c044618b5c499113
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8547711/?tool=EBI
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8547711/?tool=EBI
Publikováno v:
PLoS Pathogens, Vol 17, Iss 8, p e1009848 (2021)
PLoS Pathogens
PLoS Pathogens
HSV glycoprotein K (gK) is an essential herpes protein that contributes to enhancement of eye disease. We previously reported that gK binds to signal peptide peptidase (SPP) and that depletion of SPP reduces HSV-1 infectivity in vivo. To determine th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b988a1f1500a2935699a730d5b0c5b5a
https://doaj.org/article/d9e8a059d5a540a29a0e30648f465114
https://doaj.org/article/d9e8a059d5a540a29a0e30648f465114
Autor:
Yves Romeo, Carine Froment, Odile Burlet-Schiltz, Philippe P. Roux, Marie-Kerguelen Sarthou, Geneviève Lavoie, Charlotte Audoynaud, Thibault Houles, Maral Halladjian, Yves Henry, Sylvain Cantaloube, Oriane Lié, Emilie L. Cerezo, Anthony K. Henras
Publikováno v:
PLoS Genetics
PLoS Genetics, Public Library of Science, 2021
PLoS Genetics, Vol 17, Iss 6, p e1009583 (2021)
PLoS Genetics, Public Library of Science, 2021
PLoS Genetics, Vol 17, Iss 6, p e1009583 (2021)
Ribosome biogenesis lies at the nexus of various signaling pathways coordinating protein synthesis with cell growth and proliferation. This process is regulated by well-described transcriptional mechanisms, but a growing body of evidence indicates th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbc6dd6ce69d56164d6666eca44bd0be
https://hal.archives-ouvertes.fr/hal-03373844/document
https://hal.archives-ouvertes.fr/hal-03373844/document
Autor:
Anamika Agrawal, Elena F. Koslover
Publikováno v:
PLoS computational biology, vol 17, iss 6
PLoS Computational Biology, Vol 17, Iss 6, p e1009073 (2021)
PLoS Computational Biology
PLoS Computational Biology, Vol 17, Iss 6, p e1009073 (2021)
PLoS Computational Biology
Neurons rely on localized mitochondria to fulfill spatially heterogeneous metabolic demands. Mitochondrial aging occurs on timescales shorter than the neuronal lifespan, necessitating transport of fresh material from the soma. Maintaining an optimal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b2a2dedf58095c2601291028c58bfca
https://escholarship.org/uc/item/5td945np
https://escholarship.org/uc/item/5td945np