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pro vyhledávání: '"Biosynthetic enzyme"'
Akademický článek
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Autor:
Tibor Wenger, Kazuhito Watanabe, Yui Sasaki, Keiko Kanazawa, Koichi Shimizu, Supaart Sirikantaramas, Yoshinari Shoyama, Futoshi Taura, Satoshi Morimoto, Yukihiro Shoyama
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2022)
Cannabis sativa L. is an annual herb oldest cultivated plants as a source of fiber since about 5000 B.C. On the other hand, the cannabis flower and seed are listed in Shennong’s classic Materia Medica approximately 2000 years ago. The formulas pres
Externí odkaz:
https://doaj.org/article/7a836df649fc413e8407e78c02744923
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 23, p 12824 (2021)
Flavonoids are an important class of secondary metabolites widely found in plants, contributing to plant growth and development and having prominent applications in food and medicine. The biosynthesis of flavonoids has long been the focus of intense
Externí odkaz:
https://doaj.org/article/fc6376e2837d49cfb21082af8b7d2a5e
Publikováno v:
Frontiers in Genetics, Vol 9 (2018)
Acute intermittent porphyria (AIP) is a rare hereditary metabolic disease with an autosomal dominant mode of inheritance. Germline mutations of HMBS gene causes AIP. Mutation of HMBS gene results into the partial deficiency of the heme biosynthetic e
Externí odkaz:
https://doaj.org/article/2605f8f226124d16b3db173e087526b9
Akademický článek
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Autor:
Wilfred A. van der Donk, Chunyu Wu
Publikováno v:
Curr Opin Biotechnol
Natural products have historically been important lead sources for drug development, particularly to combat infectious diseases. Increasingly, their structurally complex scaffolds are also envisioned as leads for applications for which they did not e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfb88c9db139c3ad842ff64751fdeec0
https://doi.org/10.1016/j.copbio.2020.12.022
https://doi.org/10.1016/j.copbio.2020.12.022
Autor:
Xiuyu Liu, Zhimin Hu, Juan Guo, Mei Tian, Baolong Jin, Wei Gao, Luqi Huang, Guanghong Cui, Ying Ma
Publikováno v:
Medicinal Research Reviews. 41:2971-2997
Diterpenoids, including more than 18,000 compounds, represent an important class of metabolites that encompass both phytohormones and some industrially relevant compounds. These molecules with complex, diverse structures and physiological activities,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1dd42f559b01d4014c8eddf838d38b2c
https://doi.org/10.1002/med.21816
https://doi.org/10.1002/med.21816
Publikováno v:
Natural Product Reports
Covering: 2016 to 2021 With genetic information available for hundreds of thousands of organisms in publicly accessible databases, scientists have an unprecedented opportunity to meticulously survey the diversity and inner workings of life. The natur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ad7dba4babc266a09a0cd0be15a45c7
https://doi.org/10.1039/d1np00032b
https://doi.org/10.1039/d1np00032b
Publikováno v:
RSC Chemical Biology
Alkyne-containing natural products are important molecules that are widely distributed in microbes and plants. Inspired by the advantages of acetylenic products used in the fields of medicinal chemistry, organic synthesis and material science, great
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::880ab2864c0e756b57b4fa5ed0f39978
https://doi.org/10.1039/d0cb00190b
https://doi.org/10.1039/d0cb00190b
Publikováno v:
RSC Advances. 11:5291-5294
Funding: We thank EPSRC (EP/R013799/1) for a grant (DB) and the University of St Andrews for a Studentship (XF). The isolation of three adenosine based metabolites 6–8 from Streptomyces calvus is reported. The metabolites are structurally related t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a9175153c65e3999307d001119a3f7b
https://doi.org/10.1039/d1ra00235j
https://doi.org/10.1039/d1ra00235j