Zobrazeno 1 - 10
of 288
pro vyhledávání: '"Biorientation"'
Autor:
Aamir Ali, P. Todd Stukenberg
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Cell division events require regulatory systems to ensure that events happen in a distinct order. The classic view of temporal control of the cell cycle posits that cells order events by linking them to changes in Cyclin Dependent Kinase (CDK) activi
Externí odkaz:
https://doaj.org/article/68ec4db485db498b9064c786f6ff992b
Autor:
Tomoyuki U. Tanaka, Tongli Zhang
Publikováno v:
Cells, Vol 11, Iss 9, p 1462 (2022)
For correct chromosome segregation in mitosis, eukaryotic cells must establish chromosome biorientation where sister kinetochores attach to microtubules extending from opposite spindle poles. To establish biorientation, any aberrant kinetochore–mic
Externí odkaz:
https://doaj.org/article/a3cc65d27e6441b69899f1c65819dd17
Autor:
Vasso Makrantoni, Adam Ciesiolka, Conor Lawless, Josefin Fernius, Adele Marston, David Lydall, Michael J. R. Stark
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 7, Iss 9, Pp 3203-3215 (2017)
The chromosomal passenger complex (CPC) is a key regulator of eukaryotic cell division, consisting of the protein kinase Aurora B/Ipl1 in association with its activator (INCENP/Sli15) and two additional proteins (Survivin/Bir1 and Borealin/Nbl1). Her
Externí odkaz:
https://doaj.org/article/6d523842358f4a3a8279c80c986ab2e2
Akademický článek
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Publikováno v:
Molecular & Cellular Oncology, Vol 6, Iss 6 (2019)
Polo-like kinase 1 (PLK1) plays a fundamental role in the spatiotemporal control of mitosis. Cells lacking PLK1 activity exhibit characteristic chromosome misalignment due to defects in microtubule-kinetochore organization and attachment. In our rece
Externí odkaz:
https://doaj.org/article/818042fae8f54ee3b327576e14637700
Autor:
Giorgia Benzi, Simonetta Piatti
Publikováno v:
Current Genetics
Current Genetics, Springer Verlag, 2020, 66 (6), pp.1037-1044. ⟨10.1007/s00294-020-01091-x⟩
Current Genetics, Springer Verlag, 2020, 66 (6), pp.1037-1044. ⟨10.1007/s00294-020-01091-x⟩
International audience; During mitosis, the identical sister chromatids of each chromosome must attach through their kinetochores to microtubules emanating from opposite spindle poles. This process, referred to as chromosome biorientation, is essenti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1ad6c56d87b6f216322aa9d105dfa34
https://doi.org/10.1007/s00294-020-01091-x
https://doi.org/10.1007/s00294-020-01091-x
Akademický článek
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Autor:
Fioranna Renda, Alexey Khodjakov
Publikováno v:
Seminars in cell & developmental biology
Mitotic spindle is a self-assembling macromolecular machine responsible for the faithful segregation of chromosomes during cell division. Assembly of the spindle is believed to be governed by the ‘Search & Capture’ (S&C) principle in which dynami
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b9d0f531794721575b984740a69be07
https://doi.org/10.1016/j.semcdb.2021.03.016
https://doi.org/10.1016/j.semcdb.2021.03.016
Publikováno v:
Molecular Microbiology. 116:1079-1098
Shugoshin proteins are evolutionarily conserved across eukaryotes, with some species-specific cellular functions, ensuring the fidelity of chromosome segregation. They act as adaptors at various subcellular locales to mediate several protein-protein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05dc5b813337989d0cc10b774a2a133b
https://doi.org/10.1111/mmi.14796
https://doi.org/10.1111/mmi.14796
Akademický článek
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