Zobrazeno 1 - 10
of 673
pro vyhledávání: '"Bioprocess development"'
Publikováno v:
Current Issues in Molecular Biology, Vol 46, Iss 9, Pp 10112-10129 (2024)
p-Coumaric acid (p-CA) is a valuable compound with applications in food additives, cosmetics, and pharmaceuticals. However, traditional production methods are often inefficient and unsustainable. This study focuses on enhancing p-CA production effici
Externí odkaz:
https://doaj.org/article/95848c99097a4ad980882e1bce5a1eb9
Autor:
Lucas Kaspersetz, Britta Englert, Fabian Krah, Ernesto C. Martinez, Peter Neubauer, M. Nicolas Cruz Bournazou
Publikováno v:
SLAS Technology, Vol 29, Iss 6, Pp 100214- (2024)
In the last decades, robotic cultivation facilities combined with automated execution of workflows have drastically increased the speed of research in biotechnology. In this work, we present the design and deployment of a digital infrastructure for r
Externí odkaz:
https://doaj.org/article/9076da6cd3ce46128e3087e99a9f4255
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 12 (2024)
Viral products keep gaining importance in multiple therapeutic fields. Considering the scale and production slot limitations, optimizing the outcome of every manufacturing batch is essential to minimize costs and make this therapeutic modality broadl
Externí odkaz:
https://doaj.org/article/03d3e90ad5e5409ca7e7051db8fc296a
Autor:
Diepiriye G. Iworima, Robert K. Baker, Cara Ellis, Chris Sherwood, Lisa Zhan, Alireza Rezania, James M. Piret, Timothy J. Kieffer
Publikováno v:
Stem Cell Research & Therapy, Vol 15, Iss 1, Pp 1-27 (2024)
Abstract Background Diabetes is a disease affecting over 500 million people globally due to insulin insufficiency or insensitivity. For individuals with type 1 diabetes, pancreatic islet transplantation can help regulate their blood glucose levels. H
Externí odkaz:
https://doaj.org/article/eef5378a3b1e42df99f87e9d84023768
Autor:
Laura M. Helleckes, Debora Puchta, Hannah Czech, Holger Morschett, Bertram Geinitz, Wolfgang Wiechert, Marco Oldiges
Publikováno v:
Microbial Cell Factories, Vol 22, Iss 1, Pp 1-15 (2023)
Abstract Background Modern genome editing enables rapid construction of genetic variants, which are further developed in Design-Build-Test-Learn cycles. To operate such cycles in high throughput, fully automated screening, including cultivation and a
Externí odkaz:
https://doaj.org/article/036c71c2bf23479a8d56b4e6bf52df5a
Autor:
Riekje Biermann, Sascha Beutel
Publikováno v:
Engineering in Life Sciences, Vol 23, Iss 11, Pp n/a-n/a (2023)
Abstract The increased occurrence of antibiotic resistance and the harmful use of pesticides are a major problem of modern times. A ban on the use of antibiotics as growth promoters in animal breeding has put a focus on the probiotics market. Probiot
Externí odkaz:
https://doaj.org/article/f45abd5553e44b0aa234acd20da66add
Publikováno v:
Engineering in Life Sciences, Vol 23, Iss 10, Pp n/a-n/a (2023)
Abstract Bacillus coagulans is a promising probiotic, because it combines probiotic properties of Lactobacillus and the ability of Bacillus to form endospores. Due to this hybrid relationship, cultivation of this organism is challenging. As the probi
Externí odkaz:
https://doaj.org/article/e497828011bc41eb8d87c86f257a4002
Publikováno v:
Bioengineering, Vol 11, Iss 2, p 107 (2024)
Miniaturized cultivation systems offer the potential to enhance experimental throughput in bioprocess development. However, they usually lack the miniaturized pumps necessary for fed-batch mode, which is commonly employed in industrial bioprocesses.
Externí odkaz:
https://doaj.org/article/1c381ce485f74f36a6a0ded6589967d2
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