Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Biophysics/Structural Genomics"'
Publikováno v:
PLoS Biology
PLoS Biology, Vol 9, Iss 2, p e1000589 (2011)
PLoS Biology, Vol 9, Iss 2, p e1000589 (2011)
Crystallographic, biochemical, and genetic studies reveal the mechanism of Rap protein phosphatase activity within the phosphorelay pathway leading to sporulation in Bacillus species.
Bacterial Rap family proteins have been most extensively stud
Bacterial Rap family proteins have been most extensively stud
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd3c3e646c7cfd25bcbd6bf1d00bdcc7
http://europepmc.org/articles/PMC3035606
http://europepmc.org/articles/PMC3035606
Publikováno v:
PLoS Genetics
PLoS Genetics, Vol 7, Iss 2, p e1001315 (2011)
PLoS Genetics, Vol 7, Iss 2, p e1001315 (2011)
Here we investigate the correlations between coding sequence substitutions as a function of their separation along the protein sequence. We consider both substitutions between the reference genomes of several Drosophilids as well as polymorphisms in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9600a4d95063027624a3bbbca3bc1ed
Autor:
Jérôme Boulanger, Atsushi Matsuda, Peter M. Carlton, Charles Kervrann, Lin Shao, Peter Kner, John W. Sedat, David A. Agard
Publikováno v:
PloS one, vol 5, iss 9
PLoS ONE
PLoS ONE, Public Library of Science, 2010, 5 (9), pp.e12768. ⟨10.1371/journal.pone.0012768⟩
PLoS ONE, Vol 5, Iss 9, p e12768 (2010)
PLoS ONE, 2010, 5 (9), pp.e12768. ⟨10.1371/journal.pone.0012768⟩
PLoS ONE
PLoS ONE, Public Library of Science, 2010, 5 (9), pp.e12768. ⟨10.1371/journal.pone.0012768⟩
PLoS ONE, Vol 5, Iss 9, p e12768 (2010)
PLoS ONE, 2010, 5 (9), pp.e12768. ⟨10.1371/journal.pone.0012768⟩
International audience; Photoactivated localization microscopy (PALM) and related fluorescent biological imaging methods are capable of providing very high spatial resolutions (up to 20 nm). Two major demands limit its widespread use on biological sa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e4c457d468faef0426d2db521f12838
https://escholarship.org/uc/item/1m48695s
https://escholarship.org/uc/item/1m48695s
Publikováno v:
PLoS ONE
PLoS ONE, Vol 5, Iss 9 (2010)
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
PLoS ONE, Vol 5, Iss 9 (2010)
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Soluble proteins must maintain backbone hydrogen bonds (BHBs) water-tight to ensure structural integrity. This protection is often achieved by burying the BHBs or wrapping them through intermolecular associations. On the other hand, water has low coo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42839b2af651625a2d5513f300caeec9
http://europepmc.org/articles/PMC2941462
http://europepmc.org/articles/PMC2941462
Autor:
Amir Masoudi, Wenjin Guo, Thomas E. Edwards, Stephen N. Hewitt, Isabelle Phan, David J. Leibly, Shellie H. Dieterich, Wesley C. Van Voorhis, Jan Abendroth, Bart L. Staker, Samuel I. Miller, Angela Kelley, Peter J. Myler, Mitch Brittnacher, Lance Stewart
Publikováno v:
PLoS ONE
PLoS ONE, Vol 5, Iss 9 (2010)
PLoS ONE, Vol 5, Iss 9 (2010)
Background Pathogenic bacteria adhere to the host cell surface using a family of outer membrane proteins called Trimeric Autotransporter Adhesins (TAAs). Although TAAs are highly divergent in sequence and domain structure, they are all conceptually c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::622b37665a0c12e75107046b0e04f83b
http://europepmc.org/articles/PMC2942831
http://europepmc.org/articles/PMC2942831
Publikováno v:
PLoS ONE, Vol 5, Iss 8, p e12069 (2010)
PLoS ONE
PLoS ONE
Genomic correlates of evolutionary adaptation to very low or very high optimal growth temperature (OGT) values have been the subject of many studies. Whereas these provided a protein-structural rationale of the activity and stability of globular prot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5411d5ce033fdb6709744950c48fef1f
https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20711457/pdf/?tool=EBI
https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20711457/pdf/?tool=EBI
Autor:
Tara L. Davis, Hui Ouyang, Farrell MacKenzie, Sirano Dhe-Paganon, P.J. Finerty, Ragika Paramanathan, John R. Walker, Wolfram Tempel, Elan Z. Eisenmesser, Galina Bernstein, Wen Hwa Lee, Valérie Campagna-Slater
Publikováno v:
PLoS Biology, Vol 8, Iss 7, p e1000439 (2010)
PLoS Biology
PLoS Biology
Peptidyl-prolyl isomerases catalyze the conversion between cis and trans isomers of proline. The cyclophilin family of peptidyl-prolyl isomerases is well known for being the target of the immunosuppressive drug cyclosporin, used to combat organ trans
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55f74c49dfe67189a1d653cd89ce50d5
https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20676357/pdf/?tool=EBI
https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20676357/pdf/?tool=EBI
Publikováno v:
PLoS ONE, Vol 5, Iss 5, p e10410 (2010)
PLoS ONE
PLoS ONE, Public Library of Science, 2010, 5 (5), pp.e10410. ⟨10.1371/journal.pone.0010410⟩
PLoS ONE
PLoS ONE, Public Library of Science, 2010, 5 (5), pp.e10410. ⟨10.1371/journal.pone.0010410⟩
International audience; BACKGROUND: Protein fold recognition usually relies on a statistical model of each fold; each model is constructed from an ensemble of natural sequences belonging to that fold. A complementary strategy may be to employ sequenc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd6c32bee0edab9c1ccf018b6ff38fc5
https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20463972/?tool=EBI
https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20463972/?tool=EBI
Autor:
Bert Poolman, Jan Kok, Joao Coelho Pinto, Eric R. Geertsma, Ravi K. R. Marreddy, Hjalmar P. Permentier
Publikováno v:
PLoS ONE, Vol 5, Iss 4, p e10317 (2010)
PLoS ONE; Vol 5
PLoS ONE
PLoS ONE, 5(4):10317. PUBLIC LIBRARY SCIENCE
PLoS ONE; Vol 5
PLoS ONE
PLoS ONE, 5(4):10317. PUBLIC LIBRARY SCIENCE
Background: Understanding the biogenesis pathways for the functional expression of recombinant proteins, in particular membrane proteins and complex multidomain assemblies, is a fundamental issue in cell biology and of high importance for future prog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b3c98ecdde3f96f4297227ee1224fe0
https://research.rug.nl/en/publications/99278e07-47fd-44e6-a0c5-852b5b47f2ab
https://research.rug.nl/en/publications/99278e07-47fd-44e6-a0c5-852b5b47f2ab
Autor:
João Claudio Gonçalves Freire, Eleonora Kurtenbach, Claudio A. Masuda, Tatiana Domitrovic, Kalle Gehring, Marcius S. Almeida, Edna Matta-Camacho, Guennadi Kozlov, Georgia C. Atella, Mónica Montero-Lomelí
Publikováno v:
PLoS ONE
PLoS ONE, Vol 5, Iss 6, p e11163 (2010)
PLoS ONE, Vol 5, Iss 6, p e11163 (2010)
The genome of Saccharomyces cerevisiae is arguably the best studied eukaryotic genome, and yet, it contains approximately 1000 genes that are still relatively uncharacterized. As the majority of these ORFs have no homologs with characterized sequence
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e1e58ef0842e25af5c6546fa54b739e
https://pubmed.ncbi.nlm.nih.gov/20567505
https://pubmed.ncbi.nlm.nih.gov/20567505