Zobrazeno 1 - 10 of 281 pro vyhledávání: '"Biomolecular Analysis"'
1
A Kinetic Degradation Study of Curcumin in Its Free Form and Loaded in Polymeric Micelles
Autor: Naksuriya, Ornchuma, van Steenbergen, Mies J., Sastre Torano, Javier, Okonogi, Siriporn, Hennink, Wim E., Biomolecular Analysis, Pharmaceutics, Sub General Pharmaceutics, Sub Drug delivery, Afd Chemical Biology and Drug Discovery, Sub Biomolecular analysis, Dep Farmaceutische wetenschappen
Publikováno v: The AAPS journal, 18(3), 777. Springer New York LLC
Curcumin, a phenolic compound, possesses many pharmacological activities and is under clinical evaluation to treat different diseases. However, conflicting data about its stability have been reported. In this study, the kinetic degradation of curcumi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d97f1588cfb2f321f928361c1f6ca6de
https://doi.org/10.1208/s12248-015-9863-0
Zobrazit plný text záznamu
2
Enantioselective analysis of proteinogenic amino acids in cerebrospinal fluid by capllary electrophoresis-mass spectrometry
Autor: Prior, Amir, Sánchez-Hernández, Laura, Sastre-Toraño, Javier, Marina, Maria Luisa, de Jong, Gerhardus J., Somsen, Govert W., Biomolecular Analysis, Afd Chemical Biology and Drug Discovery, Sub Biomolecular analysis
Publikováno v: Electrophoresis, 37(17-18), 2410. Wiley-VCH Verlag
Prior, A, Sanchez-Hernandez, L, Sastre-Torano, J, Luisa Marina, M, de Jong, G J & Somsen, G W 2016, ' Enantioselective analysis of proteinogenic amino acids in cerebrospinal fluid by capllary electrophoresis-mass spectrometry. ', Electrophoresis, vol. 37, no. 17-18, pp. 2410-2419 . https://doi.org/10.1002/elps.201600015
Electrophoresis, 37(17-18), 2410-2419. Wiley-VCH Verlag
d-Amino acids (AAs) are increasingly being recognized as essential molecules in biological systems. Enantioselective analysis of proteinogenic AAs in biological samples was accomplished by CE-MS employing β-CD as chiral selector and ESI via sheath-l
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e93d5d66f84774b742edd23a794fc0d
https://hdl.handle.net/1871.1/1826f169-ce80-4102-bbef-85175aafe877
Zobrazit plný text záznamu
3
Methyleneation of peptides by N, N, N, N -tetramethylethylenediamine (TEMED) under conditions used for free radical polymerization: A mechanistic study
Autor: Shirangi, Mehrnoosh, Sastre Toraño, Javier, Sellergren, Börje, Hennink, Wim E., Somsen, Govert W., Van Nostrum, Cornelus F., Biomolecular Analysis, Pharmaceutics, Sub General Pharmaceutics, Sub Biomolecular analysis, Sub Drug delivery
Publikováno v: Shirangi, M, Sastre Toraño, J, Sellergren, B, Hennink, W E, Somsen, G W & Van Nostrum, C F 2015, ' Methyleneation of peptides by N, N, N, N-tetramethylethylenediamine (TEMED) under conditions used for free radical polymerization : A mechanistic study ', Bioconjugate chemistry, vol. 26, no. 1, pp. 90-100 . https://doi.org/10.1021/bc500445d
Bioconjugate Chemistry, 26(1), 90. American Chemical Society : Division of Carbohydrate Chemistry
Bioconjugate chemistry, 26(1), 90-100. American Chemical Society
Free radical polymerization is often used to prepare protein and peptide-loaded hydrogels for the design of controlled release systems and molecular imprinting materials. Peroxodisulfates (ammonium peroxodisulfates (APS) or potassium peroxodisulfates
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7233dbeed2e5151b50b15ff08e40c3eb
https://dspace.library.uu.nl/handle/1874/308745
Zobrazit plný text záznamu
4
Evaluation of fritless solid-phase extraction coupled on-line with capillary electrophoresis-mass spectrometry for the analysis of opioid peptides in cerebrospinal fluid
Autor: Medina-Casanellas, Silvia, Tak, Yvonne H, Benavente, Fernando, Sanz-Nebot, Victoria, Sastre Toraño, Javier, Somsen, Govert W, de Jong, Gerhardus J, Sub Biomolecular analysis, Molecular Pharmacy, Biomolecular Analysis
Publikováno v: Medina-Casanellas, S, Tak, Y, Benavente, F, Sanz-Nebot, V, Sastre Torano, J, Somsen, G W & de Jong, G J 2014, ' Evaluation of fritless solid-phase extraction coupled
with capillary electrophoresis-mass spectrometry for the analysis of opioid peptides in cerebrospinal fluid ', Electrophoresis, vol. 35, pp. 2996-3002 . https://doi.org/10.1002/elps.201400293
Electrophoresis, 35, 2996-3002. Wiley-VCH Verlag
Electrophoresis, 35(20), 2996. Wiley-VCH Verlag
Fritless SPE on-line coupled to CE with UV and MS detection (SPE-CE-UV and SPE-CE-MS) was evaluated for the analysis of opioid peptides. A microcartridge of 150 μm id was packed with a C18 sorbent (particle size > 50 μm), which was retained between
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49c72255ae9fd6879eb28c181d3e4db0
https://dspace.library.uu.nl/handle/1874/308478
Zobrazit plný text záznamu
5
CE-MS for metabolomics: Developments and applications in the period 2014-2016
Autor: Ramautar, Rawi, Somsen, Govert W, de Jong, Gerhardus J, Biomolecular Analysis, Sub Biomolecular analysis
Publikováno v: Electrophoresis, 38(1), 190. Wiley-VCH Verlag
CE-MS can be considered a useful analytical technique for the global profiling of (highly) polar and charged metabolites in various samples. Over the past few years, significant advancements have been made in CE-MS approaches for metabolomics studies
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=narcis______::bfad49eee357af896624117c7c28b16b
https://dspace.library.uu.nl/handle/1874/362223
Zobrazit plný text záznamu
6
Quality and Batch-to-Batch Consistency of Original and Biosimilar Epoetin Products
Autor: Halim, Liem Andhyk, Brinks, Vera, Jiskoot, Wim, Romeijn, Stefan, Haselberg, Rob, Burns, Chris, Wadhwa, Meenu, Schellekens, Huub, Sub General Pharmaceutics, Sub Biotechnological drugs, Sub Biomolecular analysis, Pharmaceutics
Publikováno v: Journal of Pharmaceutical Sciences, 105(2), 542. John Wiley and Sons Inc.
Andhyk Halim, L, Brinks, V, Jiskoot, W, Romeijn, S, Haselberg, R, Burns, C, Wadhwa, M & Schellekens, H 2016, ' Quality and barch-to-batch consistency of original and biosimilar epoetin products. ', Journal of Pharmaceutical Sciences, vol. 105, pp. 542-550 . https://doi.org/10.1016/j.xphs.2015.10.019
Journal of Pharmaceutical Sciences, 105, 542-550. John Wiley and Sons Inc.
Comprehensive physicochemical characterization and biological assays are essential parts in assessing quality attributes of biologicals. Here, we compared the quality of different marketed recombinant human erythropoietin (epoetin) products: originat
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::473ff30a780201396695afe2db984786
http://hdl.handle.net/1887/43709
Zobrazit plný text záznamu
8
Quality of Original and Biosimilar Epoetin Products
Autor: Brinks, V., Hawe, A., Basmeleh, A.H.H., Joachin-Rodriguez, L., Haselberg, R., Somsen, G.W., Jiskoot, W., Schellekens, H., Advanced drug delivery systems/drug targeting, Biomolecular Analysis, Innovation Studies, Farmaceutische Analyse, Pharmaceutics, Sub Biotechnological drugs, Sub Biomolecular analysis, Dep Farmaceutische wetenschappen
Publikováno v: Brinks, V, Hawe, A, Basmeleh, A H H, Joachin-Rodriguez, L, Haselberg, R, Somsen, G W, Jiskoot, W & Schellekens, H 2011, ' Quality of Original and Biosimilar Epoetin Products ', Pharmaceutical research, vol. 28, no. 2, pp. 386-393 . https://doi.org/10.1007/s11095-010-0288-2
Pharmaceutical research, 28(2), 386-393. Springer New York
Pharmaceutical Research, 28(2), 386. Springer New York LLC
Pharmaceutical Research
Purpose To compare the quality of therapeutic erythropoietin (EPO) products, including two biosimilars, with respect to content, aggregation, isoform profile and potency. Methods Two original products, Eprex (epoetin alfa) and Dynepo (epoetin delta),
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b324fd00d54de7c994bd8c1429cb1fd5
https://research.vu.nl/en/publications/39260e3c-3373-4c09-9ec3-ce00c2bc94a7
Zobrazit plný text záznamu
9
Advances in capillary electrophoresis: In-line preconcentration for biomedical analysis. Impurity profiling of heparin
Autor: van der Hoorn, Y.H., Sub Biomolecular analysis, Biomolecular Analysis
Capillary electrophoresis (CE) has shown to be highly suitable for the analysis of polar and ionogenic compounds in biomedical and pharmaceutical samples. Separation with CE is based on the charge-to-size ratio of analytes. The application of CE for
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=narcis______::2f9ff0ae668cef49825500de1e86e024
https://dspace.library.uu.nl/handle/1874/318099
Zobrazit plný text záznamu
10
Analysis of caffeine and paraxanthine in human saliva with ultra-high-performance liquid chromatography for CYP1A2 phenotyping
Autor: Jordan, Nan Yeun, Mimpen, Jolet Y., van den Bogaard, Willie J. M., Flesch, Frits M., van de Meent, Michiel H. M., Torano, Javier Sastre, Sub Biomolecular analysis, Sub Onderwijsinstituut Farmacie, Medicinal Chemistry and Chemical Biology
Publikováno v: Journal of chromatography. B, 995, 70. Elsevier
Cytochrome P450 1A2 (CYP1A2) plays an important role in drug metabolism. Caffeine (CAF) is converted into paraxanthine (PX) by this enzyme and is used as a xenobiotic substrate to determine the CYP1A2 phenotype in humans. A method for the quantificat
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5aca35aaeebd6709ce9dfcc874fe4310
https://pubmed.ncbi.nlm.nih.gov/26038236
Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání

Omezení vyhledávání
Plný text Recenzováno Digitální knihovna AV ČR
Zdroje