Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Biology of Aging: Immunity and Aging"'
Autor:
Tanya Karagiannis, Todd Dowrey, Carlos Villacorta-Martin, George Murphy, Stefano Monti, Paola Sebastiani
Publikováno v:
Innovation in Aging
Age-related disability and diseases are known to be delayed in people living to 100 years or more. Changes in the immune system with age are known, including in cell type composition and gene expression differences. To further explore changes in extr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d57535f3c38deb0cd00dbb145b34e585
http://europepmc.org/articles/PMC8681487
http://europepmc.org/articles/PMC8681487
Publikováno v:
Innovation in Aging
Mosaic chromosomal alterations (mCAs) are structural alterations that include deletions, duplications, or copy-neutral loss of heterozygosity. mCAs are reported to be associated with survival, age, cancer, and cardiovascular disease. Previous studies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f570e31e6969c8da57bc7e1be78d5c0d
https://doi.org/10.1093/geroni/igab046.2544
https://doi.org/10.1093/geroni/igab046.2544
Autor:
Kian Talaei, Steven Garan, Nuno Martins, Joshua Cho, Julia Jahansooz, Puneet Bhullar, Elliott Suen, Walter Piszker
Publikováno v:
Innovation in Aging
The role of the human immune system as a factor in the aging process has led to extensive research in the field of infection biology and bioinformatics. Cell-based mathematical models have previously been used to simulate the immune system in respons
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70d7dc7c7366d8d7cedef4855435e915
http://europepmc.org/articles/PMC8681291
http://europepmc.org/articles/PMC8681291
Publikováno v:
Innovation in Aging
Insufficient serum 25-hydroxyvitamin D (25(OH)D) concentrations are associated with increased respiratory tract infections, influenza, and other infectious diseases. As the world deals with the COVID-19 pandemic, the interest of adequate serum levels
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eec187d1cbff620851eb7b67a18bbb30
http://europepmc.org/articles/PMC8681571
http://europepmc.org/articles/PMC8681571
Autor:
Chia-Ling Kuo, Luke Pilling, Janice Atkins, Jane Masoli, Joao Delgado, George Kuchel, David Melzer, Morgan Levine
Publikováno v:
Innovation in Aging
Age and disease prevalence are the two biggest risk factors for COVID-19 symptom severity and death. We therefore hypothesized that increased biological age, beyond chronological age, may be driving disease-related trends in COVID-19 severity. Using
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4669bba38a8374d43d943172d9f71ff4
http://europepmc.org/articles/PMC8680675
http://europepmc.org/articles/PMC8680675
Autor:
Marina Watowich, Kenneth Chiou, Michael Montague, Melween Martínez, James Higham, Lauren Brent, Michael Platt, Noah Snyder-Mackler
Publikováno v:
Innovation in Aging
Extreme adverse events such as natural disasters can accelerate disease progression and promote chronic inflammation. These phenotypes also increase in prevalence with age, suggesting that experiencing adversity might accelerate aging of the immune s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79c46709378ee58697b99159eeb2b5b5
http://europepmc.org/articles/PMC8680754
http://europepmc.org/articles/PMC8680754
Autor:
Ruggiero, Alistaire, Block, Masha, Vemuri, Ravichandra, DeStephanis, Darla, Das, Swapan, Kavanagh, Kylie
Publikováno v:
Innovation in Aging
Over 93 million Americans are obese and 66 million suffer from metabolic disease. Roughly 40% of obese people do not have metabolic abnormalities (metabolically health obese [MHO]), while approximately 15% of lean do (metabolically unhealthy lean [MU
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24e281fe10a7b36d2ead2a106bfe6c8b
https://doi.org/10.1093/geroni/igab046.2545
https://doi.org/10.1093/geroni/igab046.2545