Zobrazeno 1 - 10
of 1 214
pro vyhledávání: '"Bioinformatics/Computational Biology"'
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
γδ T-cells are a rare population of T-cells with both adaptive and innate-like properties. Despite their low prevalence, they have been found to be implicated various human diseases. γδ T-cell infiltration has been associated with improved clinic
Externí odkaz:
https://doaj.org/article/4d003fdcc7094e72971a427d4acca1ef
Publikováno v:
Frontiers in Plant Science, Vol 14 (2023)
Externí odkaz:
https://doaj.org/article/bb244ea7d0ef421695e092acd4a91402
Autor:
Edward F. Xie, Sarah Hilkert Rodriguez, Bingqing Xie, Mark D’Souza, Gonnah Reem, Dinanath Sulakhe, Dimitra Skondra
Publikováno v:
Frontiers in Pediatrics, Vol 11 (2023)
PurposeRetinopathy of prematurity (ROP) is the leading cause of preventable childhood blindness worldwide. Although interventions such as anti-VEGF and laser have high success rates in treating severe ROP, current treatment and preventative strategie
Externí odkaz:
https://doaj.org/article/24d787d0f1554f8eb8e3ad2d1c04c429
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
BackgroundCholangiocarcinoma (CCA) is a highly aggressive malignant tumor for which limited treatment methods and prognostic signatures are available. This study aims to identify potential therapeutic targets and prognostic biomarkers for CCA.Methods
Externí odkaz:
https://doaj.org/article/6c6640dbb96e4c0c821bd837ff6b7bbc
Autor:
Maresi, Emiliano
Gene regulatory networks (GRNs) are crucial for understanding complex biological processes and disease mechanisms, particularly in cancer. However, GRN inference remains challenging due to the intricate nature of gene interactions and limitations of
Externí odkaz:
https://hdl.handle.net/11572/411750
Publikováno v:
Frontiers in Genetics, Vol 13 (2022)
Externí odkaz:
https://doaj.org/article/3a3bdedb0916457294c648f835c84365
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Since the start of the COVID-19 pandemic, mutations have led to the emergence of new SARS-CoV-2 variants, and some of these have become prominent or dominant variants of concern. This natural course of development can have an impact on how protective
Externí odkaz:
https://doaj.org/article/96414d28266d465bb4187ecc8aca15c5
Autor:
Teng Li, Xiaocong Pang, Junyun Wang, Shouzheng Wang, Yiying Guo, Ning He, Puyuan Xing, Junling Li
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
BackgroundClinical evidence has shown that few non-small cell lung cancer (NSCLC) patients with epidermal growth factor receptor (EGFR) mutations can benefit from immunotherapy. The tumor immune microenvironment (TIME) is a significant factor affecti
Externí odkaz:
https://doaj.org/article/7551d1f544af47a682be54002b81a28f
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Identification of the antigens associated with antibodies is vital to understanding immune responses in the context of infection, autoimmunity, and cancer. Discovering antigens at a proteome scale could enable broader identification of antigens that
Externí odkaz:
https://doaj.org/article/4081611d5772442ebdf128e99c011aa0
Autor:
Robert Haase, Elnaz Fazeli, David Legland, Michael Doube, Siân Culley, Ilya Belevich, Eija Jokitalo, Martin Schorb, Anna Klemm, Christian Tischer
Publikováno v:
FEBS Letters. 596:2472-2485
Modern research in the life sciences is unthinkable without computational methods for extracting, quantifying and visualising information derived from microscopy imaging data of biological samples. In the past decade, we observed a dramatic increase