Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Biofysikalisk kemi"'
Autor:
Rosenbaum, Erik
This Thesis is a characterization study on substances having potency as drugs as well as on a lipid based drug-delivery matrix. The optical properties of newly synthesized molecules with proven pilicide properties have been characterized with several
Externí odkaz:
http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-40177
Autor:
Ådén, Jörgen
Enzymes are extraordinary molecules that can accelerate chemical reactions by several orders of magnitude. With recent advancements in structural biology together with classical enzymology the mechanism of many enzymes has become understood at the mo
Externí odkaz:
http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-36790
Autor:
Kumar, Saroj
Infrared spectroscopy detects molecular vibrations and assesses the properties of molecules and their environment. It is a powerful technique to detect ligand induced changes in biomolecules as it has distinct signals and provides different levels of
Externí odkaz:
http://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-41023
Autor:
Lindgren, Matteus
It is well known that folded proteins in water are destabilized by the addition of urea. When a protein loses its ability to perform its biological activity due to a change in its structure, it is said to denaturate. The mechanism by which urea denat
Externí odkaz:
http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-33151
Autor:
Lindberg, Marie
Hedgehog related genes have been shown to play a major role in development in all deuterostomes. In C.elegans, such genes have been found where the similarity is restricted to the C-terminal domain. This work has focused on the hedgehog related C.ele
Externí odkaz:
http://urn.kb.se/resolve?urn=urn:nbn:se:sh:diva-1996
Autor:
Elmlund, Hans
Single-particle cryo-electron microscopy (cryo-EM) is a method capable of obtaining information about the structural organization and dynamics of large macromolecular assemblies. In the late nineties, the method was suggested to have the potential of
Externí odkaz:
http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-4669
Autor:
Isaksson, Mikael
Two recently developed theories of electronic energy transfer/migration were for the first time applied to real protein systems for extracting molecular distances. The partial donor-donor energy migration (PDDEM) is an extension to the previously dev
Externí odkaz:
http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-1009
Autor:
Bokvist, Marcus
The pathogenesis of Alzheimer’s disease (AD), the most common senile dementia, is a complex process. A crucial event in AD is the aggregation of amyloid-β protein (Aβ), a cleavage product from the Amyloid Precursor Protein (APP). Aβ40, a common
Externí odkaz:
http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-969
Autor:
Marushchak, Denys
The homo and hetero dimerisation of two spectroscopically different chromophores were studied, namely: 4,4-difluoro-4-bora-3a,4a-diazas-indacene (g-BODIPY) and its 5-styryl-derivative (r-BODIPY). Various spectroscopic properties of the r-BODIPY in di
Externí odkaz:
http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-979
Autor:
Lindström, Fredrick
Interactions between peptides and biological lipid membranes play a crucial role in many cellular processes such as in the mechanism behind Alzheimer’s disease where amyloid-beta peptide (Abeta)is thought to be a key component. The initial step of
Externí odkaz:
http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-806