Targeted Anti-Biofilm Therapy: Dissecting Targets in the Biofilm Life Cycle

Autor: Fanqiang Bu, Mengnan Liu, Zixu Xie, Xinyu Chen, Guofeng Li, Xing Wang

Publikováno v: Pharmaceuticals, Vol 15, Iss 10, p 1253 (2022)

Biofilm is a crucial virulence factor for microorganisms that causes chronic infection. After biofilm formation, the bacteria present improve drug tolerance and multifactorial defense mechanisms, which impose significant challenges for the use of ant

Externí odkaz: https://doaj.org/article/90167b60a32344c8aebcd64ae43a1fd4

Elaboration on the architecture of pH-sensitive surface charge-adaptive micelles with enhanced penetration and bactericidal activity in biofilms

Autor: Xinyu Jiang, Xiangjun Chen, Baocheng Tian, Huayu He, Keke Li, Changrong Wang, Wei Hong, Rong Guo

Publikováno v: Journal of Nanobiotechnology, Vol 19, Iss 1, Pp 1-18 (2021)
Journal of Nanobiotechnology

Background Biofilm formation is one of the main reasons for persistent bacterial infections. Recently, pH-sensitive copolymers have fascinated incredible attention to tackle biofilm-related infections. However, the proper incorporation of pH-sensitiv

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5d706d88158a4942b53244a912df8b8
https://doi.org/10.1186/s12951-021-00980-8

Amine-Functionalized Mesoporous Silica Nanoparticles: A New Nanoantibiotic for Bone Infection Treatment

Autor: Jaime López Díez, María Vallet Regí, Montserrat Colilla, Isabel Izquierdo-Barba, Daniel Pedraza

Publikováno v: E-Prints Complutense. Archivo Institucional de la UCM
instname
Biomedical Glasses, Vol 4, Iss 1, Pp 1-12 (2018)
Biomedical Glasses
Biomedical Glasses, Vol 3, Iss 1, Pp 111-122 (2017)
E-Prints Complutense: Archivo Institucional de la UCM
Universidad Complutense de Madrid

This manuscript reports an effective new alternative for the management of bone infection by the development of an antibiotic nanocarrier able to penetrate bacterial biofilm, thus enhancing antimicrobial effectiveness. This nanosystem, also denoted a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b652a56e51b889f7284bb8a7b50a0fb6

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.