Zobrazeno 1 - 10
of 132
pro vyhledávání: '"Biochemistry/Molecular Evolution"'
Translational Control by RNA-RNA Interaction: Improved Computation of RNA-RNA Binding Thermodynamics
Autor:
Mückstein, Ulrike, Tafer, Hakim, Bernhart, Stephan H., Hernandez-Rosales, Maribel, Vogel, Jörg, Stadler, Peter F., Hofacker, Ivo L.
The thermodynamics of RNA-RNA interaction consists of two components: the energy necessary to make a potential binding region accessible, i.e., unpaired, and the energy gained from the base pairing of the two interaction partners. We show here that b
Externí odkaz:
https://ul.qucosa.de/id/qucosa%3A32007
https://ul.qucosa.de/api/qucosa%3A32007/attachment/ATT-0/
https://ul.qucosa.de/api/qucosa%3A32007/attachment/ATT-0/
Autor:
Prohaska, Sonja J., Stadler, Peter F.
In order to describe a cell at molecular level, a notion of a “gene” is neither necessary nor helpful. It is sufficient to consider the molecules (i.e., chromosomes, transcripts, proteins) and their interactions to describe cellular processes. Th
Externí odkaz:
https://ul.qucosa.de/id/qucosa%3A31989
https://ul.qucosa.de/api/qucosa%3A31989/attachment/ATT-0/
https://ul.qucosa.de/api/qucosa%3A31989/attachment/ATT-0/
Autor:
Rose, Dominic, Jöris, Julian, Hackermüller, Jörg, Reiche, Kristin, Li, Qiang, Stadler, Peter F.
Teleost fishes share a duplication of their entire genomes. We report here on a computational survey of structured non-coding RNAs (ncRNAs) in teleost genomes, focusing on the fate of fish-specific duplicates. As in other metazoan groups, we find evi
Externí odkaz:
https://ul.qucosa.de/id/qucosa%3A31950
https://ul.qucosa.de/api/qucosa%3A31950/attachment/ATT-0/
https://ul.qucosa.de/api/qucosa%3A31950/attachment/ATT-0/
Autor:
Perseke, Marleen, Hankeln, Thomas, Weich, Bettina, Fritzsch, Guido, Stadler, Peter F., Israelsson, Olle, Bernhard, Detlef, Schlegel, Martin
The phylogenetic position of Xenoturbella bocki has been a matter of controversy since its description in 1949. We sequenced a second complete mitochondrial genome of this species and performed phylogenetic analyses based on the amino acid sequences
Externí odkaz:
https://ul.qucosa.de/id/qucosa%3A31999
https://ul.qucosa.de/api/qucosa%3A31999/attachment/ATT-0/
https://ul.qucosa.de/api/qucosa%3A31999/attachment/ATT-0/
Autor:
Prohaska, Sonja, Stadler, Peter F.
The ParaHox cluster contains three Hox‐related homeobox genes. The evolution of this sister of the Hox‐gene clusters has been studied extensively in metazoans with a focus on its early evolution. Its fate within the vertebrate lineage, and in par
Externí odkaz:
https://ul.qucosa.de/id/qucosa%3A31988
https://ul.qucosa.de/api/qucosa%3A31988/attachment/ATT-0/
https://ul.qucosa.de/api/qucosa%3A31988/attachment/ATT-0/
Autor:
Wagner, Günter P., Takahashi, Kazuhiko, Lynch, Vincent, Prohaska, Sonja J., Fried, Claudia, Stadler, Peter F., Amemiya, Chris
In this study the molecular evolution of duplicated HoxA genes in zebrafish and fugu has been investigated. All 18 duplicated HoxA genes studied have a higher non-synonymous substitution rate than the corresponding genes in either bichir or paddlefis
Externí odkaz:
https://ul.qucosa.de/id/qucosa%3A31898
https://ul.qucosa.de/api/qucosa%3A31898/attachment/ATT-0/
https://ul.qucosa.de/api/qucosa%3A31898/attachment/ATT-0/
Autor:
Prohaska, Sonja J., Fried, Claudia, Amemiya, Chris T., Ruddle, Frank H., Wagner, Günter P., Stadler, Peter F.
The statistical analysis of phylogenetic footprints in the two known horn shark Hox clusters and the four mammalian clusters shows that the shark HoxN cluster is HoxD-like. This finding implies that the most recent common ancestor of jawed vertebrate
Externí odkaz:
https://ul.qucosa.de/id/qucosa%3A31998
https://ul.qucosa.de/api/qucosa%3A31998/attachment/ATT-0/
https://ul.qucosa.de/api/qucosa%3A31998/attachment/ATT-0/
Evolutionarily conserved non-coding genomic sequences represent a potentially rich source for the discovery of gene regulatory regions. Since these elements are subject to stabilizing selection they evolve much slower than adjacent non-functional DNA
Externí odkaz:
https://ul.qucosa.de/id/qucosa%3A31997
https://ul.qucosa.de/api/qucosa%3A31997/attachment/ATT-0/
https://ul.qucosa.de/api/qucosa%3A31997/attachment/ATT-0/
Autor:
Prohaska, Sonja, Stadler, Peter F.
Higher teleost fishes, including zebrafish and fugu, have duplicated their Hox genes relative to the gene inventory of other gnathostome lineages. The most widely accepted theory contends that the duplicate Hox clusters orginated synchronously during
Externí odkaz:
https://ul.qucosa.de/id/qucosa%3A31986
https://ul.qucosa.de/api/qucosa%3A31986/attachment/ATT-0/
https://ul.qucosa.de/api/qucosa%3A31986/attachment/ATT-0/
A synthetic proto-organism could be self-assembled by integrating a lipid proto-container with a proto-metabolic subsystem and a proto-genetic subsystem. This three-component system can use energy and nutrients by means of either redox or photo-chemi
Externí odkaz:
https://ul.qucosa.de/id/qucosa%3A31957
https://ul.qucosa.de/api/qucosa%3A31957/attachment/ATT-0/
https://ul.qucosa.de/api/qucosa%3A31957/attachment/ATT-0/