Zobrazeno 1 - 10
of 348
pro vyhledávání: '"Biochemistry/Cell Signaling and Trafficking Structures"'
Autor:
Judith M.E.M. Cosemans, Matthew T. Harper, Johan W. M. Heemskerk, Karen Gilio, Alastair W. Poole, Kellie J. Hall
Publikováno v:
PLoS ONE
PLoS ONE, Vol 3, Iss 9, p e3277 (2008)
PLoS ONE, Vol 3, Iss 9, p e3277 (2008)
BACKGROUND: PKCtheta is a novel protein kinase C isozyme, predominately expressed in T cells and platelets. PKCtheta(-/-) T cells exhibit reduced activation and PKCtheta(-/-) mice are resistant to autoimmune disease, making PKCtheta an attractive the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c0816b62cd637f333d1eaaef3e6ee83
Publikováno v:
PLoS ONE
PLoS ONE, Vol 5, Iss 4, p e10159 (2010)
PLoS ONE, Vol 5, Iss 4, p e10159 (2010)
Background: Migration of mammalian cells is a complex cell type and environment specific process. Migrating hematopoietic cells assume a rapid amoeboid like movement when exposed to gradients of chemoattractants. The underlying signaling mechanisms r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32fe56b65208ee23787b09752c7cd35f
http://doc.rero.ch/record/324654/files/volpe_plosone_2010.pdf
http://doc.rero.ch/record/324654/files/volpe_plosone_2010.pdf
Publikováno v:
PLoS ONE
Background Sphingomyelin hydrolysis in response to stress-inducing agents, and subsequent ceramide generation, are implicated in various cellular responses, including apoptosis, inflammation and proliferation, depending on the nature of the different
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::14463bf8c28ebea46d88501b705c6243
https://pubmed.ncbi.nlm.nih.gov/20352118
https://pubmed.ncbi.nlm.nih.gov/20352118
Autor:
Brendan J. Murphy, Brian J. Ferguson, Gareth W. Morgan, David C. J. Carpentier, Michael Hollinshead, Geoffrey L. Smith
Publikováno v:
PLoS Pathogens
e1000785
PLoS Pathogens, Vol 6, Iss 2, p e1000785 (2010)
e1000785
PLoS Pathogens, Vol 6, Iss 2, p e1000785 (2010)
Vaccinia virus (VACV) uses microtubules for export of virions to the cell surface and this process requires the viral protein F12. Here we show that F12 has structural similarity to kinesin light chain (KLC), a subunit of the kinesin-1 motor that bin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::459e467e46b628850b8b5c1b6f005426
Autor:
Ashley C. W. Pike, Stefan Knapp, Frank H. Niesen, P. Rellos, Wen Hwa Lee, Frank von Delft, Eidarus Salah
Publikováno v:
PLoS Biology
PLoS Biology, Vol 8, Iss 7, p e1000426 (2010)
PLoS Biology, Vol 8, Iss 7, p e1000426 (2010)
Structural and biophysical studies reveal how CaMKII kinases, which are important for cellular learning and memory, are switched on by binding of Ca2+/calmodulin.
Long-term potentiation (LTP), a long-lasting enhancement in communication between
Long-term potentiation (LTP), a long-lasting enhancement in communication between
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99a9096397fc11969fb20dfe52e0ea9a
https://doi.org/10.1371/journal.pbio.1000426
https://doi.org/10.1371/journal.pbio.1000426
Publikováno v:
PLoS Biology, Vol 8, Iss 2, p e1000306 (2010)
PLoS Biology
PLoS Biology
Analysis of the crystal structure of a phosphotransfer complex from the Rhodobacter sphaeroides chemotaxis pathway allowed reengineering of molecular recognition in a two-component signalling system.
Two-component signal transduction pathways co
Two-component signal transduction pathways co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b3e9a490d4f1e099d8aabc0b259be37
https://doi.org/10.1371/journal.pbio.1000306
https://doi.org/10.1371/journal.pbio.1000306
Autor:
Judith P. Armitage, Mark A. J. Roberts, Patrick E. McSharry, Philip K. Maini, Antonis Papachristodoulou, Elias August, Abdullah Hamadeh
Publikováno v:
PLoS Computational Biology, Vol 7, Iss 5, p e1001130 (2011)
PLoS Computational Biology, 7 (5)
PLoS Computational Biology
PLoS Computational Biology, 7 (5)
PLoS Computational Biology
Bacteria move towards favourable and away from toxic environments by changing their swimming pattern. This response is regulated by the chemotaxis signalling pathway, which has an important feature: it uses feedback to ‘reset’ (adapt) the bacteri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9172a9e82d06d75885cf38355b24c898
https://ora.ox.ac.uk/objects/uuid:03e18fda-c590-4a44-b450-f0db9526d0fe
https://ora.ox.ac.uk/objects/uuid:03e18fda-c590-4a44-b450-f0db9526d0fe
Publikováno v:
PLoS Biology, Vol 9, Iss 3, p e1000604 (2011)
PLoS Biology
PLoS Biology
The molecular dynamics of clathrin-mediated endocytosis in living cells has been mapped with an approximately ten-fold improvement in temporal accuracy, yielding new insights into the molecular mechanism.
Dual colour total internal reflection fl
Dual colour total internal reflection fl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b90f1f7cc38de7c2c7a140c166ba140f
http://europepmc.org/articles/PMC3062526?pdf=render
http://europepmc.org/articles/PMC3062526?pdf=render
Publikováno v:
PLoS Biology
PLoS Biology, Vol 9, Iss 2, p e1001012 (2011)
PLoS Biology, Vol 9, Iss 2, p e1000587 (2011)
PLoS Biology, Vol 9, Iss 2, p e1001012 (2011)
PLoS Biology, Vol 9, Iss 2, p e1000587 (2011)
X-ray crystallographic structural analyses of the bacterial transmembrane receptor LapD identify conserved molecular mechanisms that control biofilm formation in response to changes in the intracellular levels of the second messenger c-di-GMP.
T
T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05a593aaaa94ba419ab6551b5e8f5ad8
http://europepmc.org/articles/PMC3032551
http://europepmc.org/articles/PMC3032551
Histoplasma capsulatum Heat-Shock 60 Orchestrates the Adaptation of the Fungus to Temperature Stress
Autor:
Tiago J. P. Sobreira, Leonardo Nimrichter, Joshua D. Nosanchuk, Igor C. Almeida, Ernesto S. Nakayasu, Radames J. B. Cordero, Allan J. Guimarães
Publikováno v:
PLoS ONE
PLoS ONE, Vol 6, Iss 2, p e14660 (2011)
PLoS ONE, Vol 6, Iss 2, p e14660 (2011)
Heat shock proteins (Hsps) are among the most widely distributed and evolutionary conserved proteins. Hsps are essential regulators of diverse constitutive metabolic processes and are markedly upregulated during stress. A 62 kDa Hsp (Hsp60) of Histop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::509aab4d0da1320d3984cf4b476f87c1
http://europepmc.org/articles/PMC3037374
http://europepmc.org/articles/PMC3037374