Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Biocatalysis, Protein Engineering and Nanobiotechnology"'
Autor:
Hyun Suk Jung, K. R. Shin, Kyung Gyun Hwang, Jong Wook Hong, Chan Jong Yu, Jaemin Jeong, Sujin Hyung, Ji Hye Yim, Dongho Choi, Ju Young Kim
Publikováno v:
Biotechnology and Bioengineering
The emerging field of regenerative medicine has revealed that the exosome contributes to many aspects of development and disease through intercellular communication between donor and recipient cells. However, the biological functions of exosomes secr
Publikováno v:
Biotechnology and Bioengineering
Selective oxy‐functionalization of nonactivated C‐H bonds is a long‐standing “dream reaction” of organic synthesis for which chemical methodology is not well developed. Mono‐oxygenase enzymes are promising catalysts for such oxy‐functio
Publikováno v:
Biotechnology and Bioengineering
Biotechnology and Bioengineering, 116(9), 2167-2177. Wiley-Blackwell
Biotechnology and Bioengineering, 116(9), 2167-2177. Wiley-Blackwell
Enzymes often by far exceed the activity, selectivity, and sustainability achieved with chemical catalysts. One of the main reasons for the lack of biocatalysis in the chemical industry is the poor stability exhibited by many enzymes when exposed to
Publikováno v:
Biotechnology and Bioengineering
The hydrolysis of cellulose by processive cellulases, such as exocellulase TrCel7A from Trichoderma reesei, is typically characterized by an initial burst of high activity followed by a slowdown, often leading to incomplete hydrolysis of the substrat
Publikováno v:
Biotechnology and Bioengineering
Oxidative O2‐dependent biotransformations are promising for chemical synthesis, but their development to an efficiency required in fine chemical manufacturing has proven difficult. General problem for process engineering of these systems is that th
Publikováno v:
Biotechnology and Bioengineering
Chemical group‐transfer reactions by hydrolytic enzymes have considerable importance in biocatalytic synthesis and are exploited broadly in commercial‐scale chemical production. Mechanistically, these reactions have in common the involvement of a
Publikováno v:
Biotechnology and Bioengineering
Cytochrome P450 monooxygenases (P450s) promote hydroxylations in a broad variety of substrates. Their prowess in C–H bond functionalization renders P450s promising catalysts for organic synthesis. However, operating P450 reactions involve complex m
Publikováno v:
Biotechnology and Bioengineering
The D746E variant of Bifidobacterium bifidum β‐N‐acetyl‐hexosaminidase is a promising glycosynthase (engineered glycosidase deficient in hydrolase activity) for the synthesis of lacto‐N‐triose II (LNT II), a core structural unit of human m
Autor:
Robin, Julien, Gueroult, Marc, Cheikhrouhou, Randa, Guicherd, Marie, Borsenberger, Vinciane, Marty, Alain, Bordes, Florence
Publikováno v:
Biotechnology and Bioengineering
Biotechnology and Bioengineering, Wiley, 2019, 12 p. ⟨10.1002/bit.27102⟩
Biotechnology and Bioengineering, 12 p.. (2019)
Biotechnology and Bioengineering, 2019, 12 p. ⟨10.1002/bit.27102⟩
Biotechnology and Bioengineering, Wiley, 2019, 12 p. ⟨10.1002/bit.27102⟩
Biotechnology and Bioengineering, 12 p.. (2019)
Biotechnology and Bioengineering, 2019, 12 p. ⟨10.1002/bit.27102⟩
Claviceps purpurea bifunctional Δ12‐hydroxylase/desaturase, CpFAH12, and monofunctional desaturase CpFAD2, share 86% of sequence identity. To identify the underlying determinants of the hydroxylation/desaturation specificity, chimeras of these two
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::2b0da75f26ce600b0347b9027171947f
https://hal.archives-ouvertes.fr/hal-02271476
https://hal.archives-ouvertes.fr/hal-02271476
Publikováno v:
Biotechnology and Bioengineering
The large‐scale production and isolation of recombinant protein is a central element of the biotechnology industry and many of the products have proved extremely beneficial for therapeutic medicine. Escherichia coli is the microorganism of choice f