Výsledky vyhledávání - "Bio-inspired and Biomedical Materials"

Block catiomer with flexible cationic segment enhances complexation with siRNA and the delivery performance in vitro

Autor: Wenqian Yang, Kazunori Kataoka, Mitsuru Naito, Akira Matsumoto, Takuya Miyazaki, Taehun Hong, Yuji Miyahara, Chen Pengwen, Horacio Cabral, Kanjiro Miyata

Publikováno v: Science and Technology of Advanced Materials
article-version (VoR) Version of Record
Science and Technology of Advanced Materials, Vol 22, Iss 1, Pp 850-863 (2021)

RNA interference (RNAi) by small interfering RNAs (siRNAs) is a promising therapeutic approach. Because siRNA has limited intracellular access and is rapidly cleared in vivo, the success of RNAi depends on efficient delivery technologies. Particularl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::461a7311bd957529840cfbc399eb5f64
http://europepmc.org/articles/PMC8519541

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Magnetic stimulation of the angiogenic potential of mesenchymal stromal cells in vascular tissue engineering

Autor: Frederico Castelo Ferreira, Carla A.M. Portugal, Joaquim M. S. Cabral, Ana C. Manjua

Publikováno v: Science and Technology of Advanced Materials
article-version (VoR) Version of Record
Science and Technology of Advanced Materials, Vol 22, Iss 1, Pp 461-480 (2021)

The growing prevalence of vascular diseases worldwide has emphasized the need for novel tissue-engineered options concerning the development of vascularized 3D constructs. This study reports, for the first time, the use of external magnetic fields to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3711717c93338352d0778c4d86ee873
http://europepmc.org/articles/PMC8245073

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Organic modification of layered zirconium phosphate/phosphonate for controlled release of therapeutic inorganic ions

Autor: Chikara Ohtsuki, Ayae Sugawara-Narutaki, Ryoya Ito, Ryohei Kozaki, Jin Nakamura

Publikováno v: Science and Technology of Advanced Materials
article-version (VoR) Version of Record
Science and Technology of Advanced Materials, Vol 22, Iss 1, Pp 1000-1012 (2021)

The present study aims to develop a layered zirconium phosphate/phosphonate (LZP) powder to control the release of therapeutic inorganic ions. Organically modified LZPs were successfully prepared with various contents of phenyl groups via a reflux me

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4da31a5ec734f47afafb36d35760eb4
https://doi.org/10.1080/14686996.2021.1993728

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Improved anti-cancer effect of epidermal growth factor-gold nanoparticle conjugates by protein orientation through site-specific mutagenesis

Autor: Jun Nakanishi, Aiwen Zhang

Publikováno v: Science and Technology of Advanced Materials, Vol 22, Iss 1, Pp 616-626 (2021)
Science and Technology of Advanced Materials
article-version (VoR) Version of Record

Epidermal growth factor (EGF)-nanoparticle conjugates have the potential for cancer therapeutics due to the unique cytotoxic activity in cancer cells with EGF receptor (EGFR) overexpression. To gain its maximum activity, the EGF molecule should be im

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db025d7373ac5e3cac96bf9fae1633bf
https://doaj.org/article/ff01d888ae934a829c3bbc3778036aee

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Nanomaterials and their composite scaffolds for photothermal therapy and tissue engineering applications

Autor: Naoki Kawazoe, Guoping Chen, Rui Sun, Huajian Chen, Linawati Sutrisno

Publikováno v: Science and Technology of Advanced Materials, Vol 22, Iss 1, Pp 404-428 (2021)
Science and Technology of Advanced Materials
article-version (VoR) Version of Record

Photothermal therapy (PTT) has attracted broad attention as a promising method for cancer therapy with less severe side effects than conventional radiation therapy, chemotherapy and surgical resection. PTT relies on the photoconversion capacity of ph

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c242e74db4035175cb895a37a7cf3ea
https://doaj.org/article/8c6124cd4de846a5a5ee795d4dd972f0

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Mutual chemical effect of autograft and octacalcium phosphate implantation on enhancing intramembranous bone regeneration

Autor: Osamu Suzuki, Hisashi Ozaki, Kaori Tsuchiya, Yukari Shiwaku, Susumu Sakai, Ryo Hamai

Publikováno v: Science and Technology of Advanced Materials, Vol 22, Iss 1, Pp 345-362 (2021)
Science and Technology of Advanced Materials
article-version (VoR) Version of Record

This study examined the effect of a mixture of octacalcium phosphate (OCP) and autologous bone on bone regeneration in rat calvaria critical-sized defect (CSD). Mechanically mixed OCP and autologous bone granules (OCP+Auto), approximately 500 to 1000

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c899928871ec75f12ee1cc61bbe98f6e
https://doaj.org/article/69b198b297374d0887c5bb0879c11e00

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Carbonate apatite artificial bone

Autor: Kunio Ishikawa, Koichiro Hayashi

Publikováno v: Science and Technology of Advanced Materials, Vol 22, Iss 1, Pp 683-694 (2021)
Science and Technology of Advanced Materials
article-version (VoR) Version of Record

Bone apatite is not hydroxyapatite (HAp), it is carbonate apatite (CO3Ap), which contains 6–9 mass% carbonate in an apatitic structure. The CO3Ap block cannot be fabricated by sintering because of its thermal decomposition at the sintering temperat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d0afe4b9b3d821ca81dd6428f9fd4d8
https://doaj.org/article/ca0ed543f7d742dd9dca39d7b7543c5b

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Weakly acidic carboxy group-grafted β-cyclodextrin-threaded acid-degradable polyrotaxanes for modulating protein interaction and cellular internalization

Autor: Atsushi Tamura, Nobuhiko Yui, Shunyao Zhang

Publikováno v: Science and Technology of Advanced Materials, Vol 22, Iss 1, Pp 494-510 (2021)
Science and Technology of Advanced Materials
article-version (VoR) Version of Record

To improve the therapeutic potential of β-cyclodextrin (β-CD)-threaded acid-degradable polyrotaxanes (β-CD PRXs) in cholesterol-related metabolic disorders, we investigated the effect of carboxylation of β-CD PRXs on intracellular uptake. In this

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9a6df8baf27b0af5de69c002d6196d8
https://doaj.org/article/d6a930a532014e618874c0ff6469a68e

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Reduced cytotoxicity of polyethyleneimine by covalent modification of antioxidant and its application to microalgal transformation

Autor: Haruka Karita, Toru Yoshitomi, Naoki Sato, Natsumi Mori-Moriyama, Keitaro Yoshimoto

Publikováno v: Science and Technology of Advanced Materials, Vol 22, Iss 1, Pp 864-874 (2021)
Science and Technology of Advanced Materials
article-version (VoR) Version of Record

The conversion of carbon dioxide into valuable chemicals is an effective strategy for combating augmented concentrations of carbon dioxide in the environment. Microalgae photosynthetically produce valuable chemicals that are used as biofuels, sources

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d86355816bbc7c12fc70360dc1dcdde
https://doi.org/10.1080/14686996.2021.1978273

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Osteoclast and osteoblast responsive carbonate apatite coatings for biodegradable magnesium alloys

Autor: Takaya Akashi, Hideki Katayama, Naomi Noda, Sachiko Hiromoto, Tomohiko Yamazaki, Sayaka Itoh

Publikováno v: Science and Technology of Advanced Materials, Vol 21, Iss 1, Pp 346-358 (2020)
Science and Technology of Advanced Materials
article-version (VoR) Version of Record

Corrosion-control coatings which can enhance bone formation and be completely replaced by bone are attractive for biodegradable Mg alloys. Carbonate apatite (CAp) and hydroxyapatite (HAp) coatings were formed on Mg-4 wt% Y-3 wt% rare earth (WE43) all

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b709362504deeb836fdbe21dcad3fc32
https://doi.org/10.1080/14686996.2020.1761237

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