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Autor:
Kevin Anderson, Milan Kaushik, Casey A. Dougherty, Christina N. Kelly, Sriram Vaidyanathan, Rachel L. Merzel, Mallory A. van Dongen, Mark M. Banaszak Holl, Bradford G. Orr, Binyamin Jacobovitz
Publikováno v:
ACS Nano. 9:6097-6109
Cationic gene delivery agents (vectors) are important for delivering nucleotides, but are also responsible for cytotoxicity. Cationic polymers (L-PEI, jetPEI, and G5 PAMAM) at 1x to 100x the concentrations required for translational activity (protein