Meiotic outcomes of three-way translocations ascertained in cleavage-stage embryos: refinement of reproductive risks and implications for PGD.

Autor: Scriven PN; 1] Guy's & St Thomas' Centre for PGD, Guy's & St. Thomas' Hospital NHS Foundation Trust, London, UK [2] Division of Genetics & Molecular Medicine, King's College London, School of Medicine at Guy's, King's College & St Thomas' Hospitals, London, UK., Bint SM; 1] Guy's & St Thomas' Centre for PGD, Guy's & St. Thomas' Hospital NHS Foundation Trust, London, UK [2] Cytogenetics department, GSTS-Pathology, Guy's & St. Thomas' NHS Foundation Trust, London, UK., Davies AF; 1] Guy's & St Thomas' Centre for PGD, Guy's & St. Thomas' Hospital NHS Foundation Trust, London, UK [2] Cytogenetics department, GSTS-Pathology, Guy's & St. Thomas' NHS Foundation Trust, London, UK., Ogilvie CM; 1] Guy's & St Thomas' Centre for PGD, Guy's & St. Thomas' Hospital NHS Foundation Trust, London, UK [2] Division of Genetics & Molecular Medicine, King's College London, School of Medicine at Guy's, King's College & St Thomas' Hospitals, London, UK [3] Genetics Centre, Guy's & St Thomas' NHS Foundation Trust, London, UK.

Publikováno v: European journal of human genetics : EJHG [Eur J Hum Genet] 2014 Jun; Vol. 22 (6), pp. 748-53. Date of Electronic Publication: 2013 Oct 16.

Successful PGD cycles for mosaic Robertsonian translocation carriers provide insights into the mechanism of formation of the derivative chromosomes.

Autor: Bint SM; Cytogenetics Department, GSTS Pathology, Guy's Hospital, London, UK. susan.bint@gsts.com, Scriven PN, Ogilvie CM

Publikováno v: American journal of medical genetics. Part A [Am J Med Genet A] 2013 Mar; Vol. 161A (3), pp. 566-71. Date of Electronic Publication: 2013 Feb 07.