Sialic acid-based probiotic intervention in lactating mothers improves the neonatal gut microbiota and immune responses by regulating sialylated milk oligosaccharide synthesis via the gut–breast axis

Autor: Yushuang Wang, Binqi Rui, Xiaolei Ze, Yujia Liu, Da Yu, Yinhui Liu, Zhi Li, Yu Xi, Xixi Ning, Zengjie Lei, Jieli Yuan, Liang Li, Xuguang Zhang, Wenzhe Li, Yanjie Deng, Jingyu Yan, Ming Li

Publikováno v: Gut Microbes, Vol 16, Iss 1 (2024)

ABSTRACTHuman milk oligosaccharides (HMOs) are vital milk carbohydrates that help promote the microbiota-dependent growth and immunity of infants. Sialic acid (SA) is a crucial component of sialylated milk oligosaccharides (S-MOs); however, the effec

Externí odkaz: https://doaj.org/article/d00f8bb12cee4a06a711d5eadb965a5b

Limosilactobacillus reuteri HCS02-001 Attenuates Hyperuricemia through Gut Microbiota-Dependent Regulation of Uric Acid Biosynthesis and Excretion

Autor: Akbar Hussain, Binqi Rui, Hayan Ullah, Panpan Dai, Kabir Ahmad, Jieli Yuan, Yinhui Liu, Ming Li

Publikováno v: Microorganisms, Vol 12, Iss 4, p 637 (2024)

Hyperuricemia is a prevalent metabolic disorder that arises from abnormal purine metabolism and reduced excretion of uric acid (UA). The gut microbiota plays a significant role in the biosynthesis and excretion of UA. Probiotics capable of purine deg

Externí odkaz: https://doaj.org/article/5dd321abefc24c49919b7e0f7b293eec

Studies and Application of Sialylated Milk Components on Regulating Neonatal Gut Microbiota and Health

Autor: Yushuang Wang, Xiaolei Ze, Binqi Rui, Xinke Li, Nina Zeng, Jieli Yuan, Wenzhe Li, Jingyu Yan, Ming Li

Publikováno v: Frontiers in Nutrition, Vol 8 (2021)

Breast milk is rich in sialic acids (SA), which are commonly combined with milk oligosaccharides and glycoconjugates. As a functional nutrient component, SA-containing milk components have received increasing attention in recent years. Sialylated hum

Externí odkaz: https://doaj.org/article/572cf89248e54d11bfb1f9191e92769d

Gut Microbiota Promotes Immune Tolerance by Regulating RORγt+ Treg Cells in Food Allergy

Autor: Xixi Ning, Zengjie Lei, Binqi Rui, Yuyuan Li, Ming Li

Publikováno v: Advanced Gut & Microbiome Research. 2022:1-9

Food allergy is a significant public health problem troubling people, and the incidence has been on the rise in the past decade. Emerging evidence suggests an influence of the gut microbiota in susceptibility to food allergies. Epidemiological studie

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8bf381a307c67b1f26f4b536c237c67d
https://doi.org/10.1155/2022/8529578

The Intestinal Dysbiosis of Mothers with Gestational Diabetes Mellitus (GDM) and Its Impact on the Gut Microbiota of Their Newborns

Autor: Da Yu, Jingyu Yan, Ming Li, Huimin Yuan, Yushuang Wang, Xixi Ning, Zengjie Lei, Binqi Rui, Xinke Li, Jieli Yuan

Publikováno v: The Canadian Journal of Infectious Diseases & Medical Microbiology = Journal Canadien des Maladies Infectieuses et de la Microbiologie Médicale
Canadian Journal of Infectious Diseases and Medical Microbiology, Vol 2021 (2021)

Gestational diabetes mellitus (GDM) is defined as “diagnosed as impaired glucose tolerance for the first time during pregnancy,” which can lead to adverse pregnancy outcomes and produces divergent effects on mothers and newborns. In recent years,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::088142bd13ef6f20e547144b08f16755
http://europepmc.org/articles/PMC8481071