Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Binh G. Vong"'
Autor:
Marion Lanier, Xiaohu Zhang, John E. Tellew, Zhiyong Luo, Mark Santos, Raymond S. Gross, Deborah H. Slee, Emily Lin, Sandra M. Lechner, Jaimie K. Rueter, María I. Crespo, Jose-Luis Diaz, Yongsheng Chen, Siobhan Malany, Manisha Moorjani, John Saunders, John P. Williams, Binh G. Vong
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 18:5402-5405
In this report, the strategy and outcome of expanding SAR exploration to improve solubility and metabolic stability are discussed. Compound 35 exhibited excellent potency, selectivity over A(1) and improved solubility of >4 mg/mL at pH 8.0. In additi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::799d40e0876b3b15e810f1648d5b9dc2
https://doi.org/10.1016/j.bmcl.2008.09.048
https://doi.org/10.1016/j.bmcl.2008.09.048
Autor:
Paqui G. Través, G. Kenneth Lloyd, Lyle L. Moldawer, Michael A. Palladino, Sonsoles Hortelano, Binh G. Vong, Lisardo Boscá, Emmanuel A. Theodorakis, Chinmay Chowdhury, Ta Hsiang Chao, Thanh Lam, F. Rena Bahjat
Publikováno v:
ChemBioChem. 6:133-144
The synthesis and the biological evaluation of a new family diterpenes are presented. The synthetic studies were inspired by the structural framework of acanthoic acid (1) and yielded a family of compounds that were evaluated as anti-inflammatory age
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aea3b8ad8fe2434c7896d1430d4f82fb
https://doi.org/10.1002/cbic.200400089
https://doi.org/10.1002/cbic.200400089
Publikováno v:
Organic Letters. 5:1491-1494
An efficient synthetic approach to the tricyclic core 8 of lateriflorone is described. Essential to the synthesis was the implementation of a biomimetic tandem Claisen/Diels-Alder reaction that produced the desired tricyclic scaffold as a single isom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cf531aa846287c33dc13e775676cbcf
https://doi.org/10.1021/ol034276y
https://doi.org/10.1021/ol034276y
Publikováno v:
Organic Letters. 4:909-912
[reaction: see text] Two different routes to the tricyclic core of Garcinia-derived natural products are described. The first approach is based on a tandem Claisen/Diels-Alder rearrangement and delivers the desired lactone 14. The second approach, em
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::109c700d44b603eee022aa184570d450
https://doi.org/10.1021/ol017278w
https://doi.org/10.1021/ol017278w
ChemInform Abstract: Enantioselective Synthesis of the Antiinflammatory Agent (-)-Acanthoic Acid (I)
Autor:
Taotao Ling, Chinmay Chowdhury, Binh G. Vong, Emmanuel A. Theodorakis, Bryan A. Kramer, Michael A. Palladino
Publikováno v:
ChemInform. 33
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b6a3c0f7d3315cb6f9d2736328e91444
https://doi.org/10.1002/chin.200225169
https://doi.org/10.1002/chin.200225169
Autor:
Bo Liang, Adam D. Richardson, James J. La Clair, Thomas P. Brady, Matthew D Alexander, Joel S. Sandler, Santosh J. Gharpure, Alexei Polosukhin, Hai Ren Zhang, Xiaobin Ding, Madeleine M. Joullié, A. Richard Chamberlin, Chris M. Ireland, James B. Aggen, Brian M. Gulledge, Mary Kay Harper, Michael D. Burkart, P. Andrew Evans, Binh G. Vong, William Fenical, Padma Portonovo, Emmanuel A. Theodorakis, Michael S. Leonard, Jian Cui
Publikováno v:
Chembiochem : a European journal of chemical biology. 7(3)
A Central Strategy for Converting Natural Products into Fluorescent Probes Matthew D. Alexander, Michael D. Burkart, Michael S. Leonard, Padma Portonovo, Bo Liang, Xiaobin Ding, Madeleine M. Joulli!, Brian M. Gulledge, James B. Aggen, A. Richard Cham
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::049bc9f76b514a0c5296477d75bac41e
https://pubmed.ncbi.nlm.nih.gov/16432909
https://pubmed.ncbi.nlm.nih.gov/16432909
Publikováno v:
ChemInform. 35
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a311fb1322d3d701d8091d817fc308c1
https://doi.org/10.1002/chin.200447205
https://doi.org/10.1002/chin.200447205
Autor:
Sun Hee Kim, Emmanuel A. Theodorakis, Chinmay Chowdhury, Eric J. Tisdale, Binh G. Vong, Hongmei Li
Publikováno v:
ChemInform. 34
A convergent strategy toward the synthesis of lateriflorone ( 5 ) is described. Our approach is based on biosynthetic considerations and draws on a sequence of prenylation, oxygenation and Claisen reactions for the construction of chromenequinone 6 ,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::add09ae6a00fdf99977e33b2e6582f80
https://doi.org/10.1002/chin.200351207
https://doi.org/10.1002/chin.200351207
Publikováno v:
ChemInform. 34
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::322d22c761a7f2a8dc7067fcd39bfef4
https://doi.org/10.1002/chin.200337185
https://doi.org/10.1002/chin.200337185
Publikováno v:
Organic letters. 5(10)
[structure: see text] An efficient, enantioselective synthesis of the C1-C12 fragment 2 of borrelidin is presented. Construction of the "skipped" polymethylene chain of 2 was accomplished by iteration of Myers' alkylation, while formation of the C3 s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ddf6283b06ebc8abdd67d5b4f28deaff
https://pubmed.ncbi.nlm.nih.gov/12735735
https://pubmed.ncbi.nlm.nih.gov/12735735