Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Binh G. Vong"'
Autor:
Marion Lanier, Xiaohu Zhang, John E. Tellew, Zhiyong Luo, Mark Santos, Raymond S. Gross, Deborah H. Slee, Emily Lin, Sandra M. Lechner, Jaimie K. Rueter, María I. Crespo, Jose-Luis Diaz, Yongsheng Chen, Siobhan Malany, Manisha Moorjani, John Saunders, John P. Williams, Binh G. Vong
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 18:5402-5405
In this report, the strategy and outcome of expanding SAR exploration to improve solubility and metabolic stability are discussed. Compound 35 exhibited excellent potency, selectivity over A(1) and improved solubility of >4 mg/mL at pH 8.0. In additi
Autor:
Paqui G. Través, G. Kenneth Lloyd, Lyle L. Moldawer, Michael A. Palladino, Sonsoles Hortelano, Binh G. Vong, Lisardo Boscá, Emmanuel A. Theodorakis, Chinmay Chowdhury, Ta Hsiang Chao, Thanh Lam, F. Rena Bahjat
Publikováno v:
ChemBioChem. 6:133-144
The synthesis and the biological evaluation of a new family diterpenes are presented. The synthetic studies were inspired by the structural framework of acanthoic acid (1) and yielded a family of compounds that were evaluated as anti-inflammatory age
Publikováno v:
Organic Letters. 5:1491-1494
An efficient synthetic approach to the tricyclic core 8 of lateriflorone is described. Essential to the synthesis was the implementation of a biomimetic tandem Claisen/Diels-Alder reaction that produced the desired tricyclic scaffold as a single isom
Publikováno v:
Organic Letters. 4:909-912
[reaction: see text] Two different routes to the tricyclic core of Garcinia-derived natural products are described. The first approach is based on a tandem Claisen/Diels-Alder rearrangement and delivers the desired lactone 14. The second approach, em
Autor:
Bo Liang, Adam D. Richardson, James J. La Clair, Thomas P. Brady, Matthew D Alexander, Joel S. Sandler, Santosh J. Gharpure, Alexei Polosukhin, Hai Ren Zhang, Xiaobin Ding, Madeleine M. Joullié, A. Richard Chamberlin, Chris M. Ireland, James B. Aggen, Brian M. Gulledge, Mary Kay Harper, Michael D. Burkart, P. Andrew Evans, Binh G. Vong, William Fenical, Padma Portonovo, Emmanuel A. Theodorakis, Michael S. Leonard, Jian Cui
Publikováno v:
Chembiochem : a European journal of chemical biology. 7(3)
A Central Strategy for Converting Natural Products into Fluorescent Probes Matthew D. Alexander, Michael D. Burkart, Michael S. Leonard, Padma Portonovo, Bo Liang, Xiaobin Ding, Madeleine M. Joulli!, Brian M. Gulledge, James B. Aggen, A. Richard Cham
ChemInform Abstract: Enantioselective Synthesis of the Antiinflammatory Agent (-)-Acanthoic Acid (I)
Autor:
Taotao Ling, Chinmay Chowdhury, Binh G. Vong, Emmanuel A. Theodorakis, Bryan A. Kramer, Michael A. Palladino
Publikováno v:
ChemInform. 33
Publikováno v:
ChemInform. 35
Autor:
Sun Hee Kim, Emmanuel A. Theodorakis, Chinmay Chowdhury, Eric J. Tisdale, Binh G. Vong, Hongmei Li
Publikováno v:
ChemInform. 34
A convergent strategy toward the synthesis of lateriflorone ( 5 ) is described. Our approach is based on biosynthetic considerations and draws on a sequence of prenylation, oxygenation and Claisen reactions for the construction of chromenequinone 6 ,
Publikováno v:
ChemInform. 34
Publikováno v:
Organic letters. 5(10)
[structure: see text] An efficient, enantioselective synthesis of the C1-C12 fragment 2 of borrelidin is presented. Construction of the "skipped" polymethylene chain of 2 was accomplished by iteration of Myers' alkylation, while formation of the C3 s