Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Bingzheng Lu"'
Autor:
Chen Chen, YuWei Zhou, XinPeng Ning, ShengLong Li, DongDong Xue, CaiLv Wei, Zhu Zhu, LongXiang Sheng, BingZheng Lu, Yuan Li, XiaoYuan Ye, YunZhao Fu, Chuan Bai, Wei Cai, YuXuan Ding, SuiZhen Lin, GuangMei Yan, YiJun Huang, Wei Yin
Publikováno v:
Journal of Neuroinflammation, Vol 19, Iss 1, Pp 1-17 (2022)
Abstract Background Dysregulated activation of the inflammasome is involved in various human diseases including acute cerebral ischemia, multiple sclerosis and sepsis. Though many inflammasome inhibitors targeting NOD-like receptor protein 3 (NLRP3)
Externí odkaz:
https://doaj.org/article/186583cab01f48ae8a69a1cb6197adba
Autor:
Jialuo Mai, Jiayu Gu, Ying Liu, Xincheng Liu, Ke Sai, Zhijie Chen, Wanjun Lu, Xiaozhi Yang, Jingyi Wang, Cui Guo, Shuxin Sun, Fan Xing, Longxiang Sheng, Bingzheng Lu, Zhu Zhu, Hongjiaqi Sun, Dongdong Xue, Yuan Lin, Jing Cai, Yaqian Tan, Chuntao Li, Wei Yin, Lin Cao, Ying Ou‐yang, Pengxin Qiu, Xingwen Su, Guangmei Yan, Jiankai Liang, Wenbo Zhu
Publikováno v:
Molecular Oncology, Vol 13, Iss 7, Pp 1589-1604 (2019)
Activation of the cyclic adenosine monophosphate/protein kinase A (cAMP/PKA) pathway induces glial differentiation of glioblastoma (GBM) cells, but the mechanism by which microRNA (miRNA) regulate this process remains poorly understood. In this study
Externí odkaz:
https://doaj.org/article/d7ddbd73683b41da8f7ee1aaf43eb0cc
Autor:
Fan Xing, Yizhao Luan, Jing Cai, Sihan Wu, Jialuo Mai, Jiayu Gu, Haipeng Zhang, Kai Li, Yuan Lin, Xiao Xiao, Jiankai Liang, Yuan Li, Wenli Chen, Yaqian Tan, Longxiang Sheng, Bingzheng Lu, Wanjun Lu, Mingshi Gao, Pengxin Qiu, Xingwen Su, Wei Yin, Jun Hu, Zhongping Chen, Ke Sai, Jing Wang, Furong Chen, Yinsheng Chen, Shida Zhu, Dongbing Liu, Shiyuan Cheng, Zhi Xie, Wenbo Zhu, Guangmei Yan
Publikováno v:
Cell Reports, Vol 18, Iss 2, Pp 468-481 (2017)
Summary: Glioblastoma multiforme (GBM) is among the most aggressive of human cancers. Although differentiation therapy has been proposed as a potential approach to treat GBM, the mechanisms of induced differentiation remain poorly defined. Here, we e
Externí odkaz:
https://doaj.org/article/3968fd8bebf440b692cae7ea5b0da112
Synthesis of taurine–fluorescein conjugate and evaluation of its retina-targeted efficiency in vitro
Autor:
Meihong Huang, Jiaqi Song, Bingzheng Lu, Huizhi Huang, Yizhen Chen, Wei Yin, Wenbo Zhu, Xinwen Su, Chuanbin Wu, Haiyan Hu
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 4, Iss 6, Pp 447-453 (2014)
In this work, retinal penetration of fluorescein was achieved in vitro by covalent attachment of taurine to fluorescein, yielding the F–Tau conjugate. Nuclear magnetic resonance (NMR) and high resolution mass spectrometry (HRMS) were used to confir
Externí odkaz:
https://doaj.org/article/20f0a2ba471d49abb6f1b54719ffb9ee
Publikováno v:
PLoS ONE, Vol 12, Iss 10, p e0184578 (2017)
Mycoplasma infection has been reported to be associated with cancer migration, invasion, epithelial-mesenchymal transition as well as the resistance to nucleoside analogues chemotherapeutic drugs. In this study, we found that the sensitivity of hepat
Externí odkaz:
https://doaj.org/article/6d0f8b36c1ed4d0ea3927310a1151a67
Autor:
Fan Xing, Yizhao Luan, Jing Cai, Sihan Wu, Jialuo Mai, Jiayu Gu, Haipeng Zhang, Kai Li, Yuan Lin, Xiao Xiao, Jiankai Liang, Yuan Li, Wenli Chen, Yaqian Tan, Longxiang Sheng, Bingzheng Lu, Wanjun Lu, Mingshi Gao, Pengxin Qiu, Xingwen Su, Wei Yin, Jun Hu, Zhongping Chen, Ke Sai, Jing Wang, Furong Chen, Yinsheng Chen, Shida Zhu, Dongbing Liu, Shiyuan Cheng, Zhi Xie, Wenbo Zhu, Guangmei Yan
Publikováno v:
Cell Reports, Vol 23, Iss 9, Pp 2832-2833 (2018)
Externí odkaz:
https://doaj.org/article/40b43ec9dddd49d687e552cf48854352
Autor:
Longxiang Sheng, Bingzheng Lu, Hui Chen, Yun Du, Chen Chen, Wei Cai, Yang Yang, Xuyan Tian, Zhaofeng Huang, Wei Chi, Suizhen Lin, Guangmei Yan, Wei Yin
Publikováno v:
Marine Drugs, Vol 17, Iss 5, p 267 (2019)
High intraocular pressure (IOP)-induced retinal ischemia leads to acute glaucoma, which is one of the leading causes of irreversible visual-field loss, characterized by loss of retinal ganglion cells (RGCs) and axonal injury in optic nerves (ONs). Ox
Externí odkaz:
https://doaj.org/article/2d3d29b6a0014bcc9b9f668a1c3a57cd
Autor:
DongDong Xue, CaiLv Wei, YueHan Zhou, Kai Wang, YuWei Zhou, Chen Chen, Yuan Li, LongXiang Sheng, BingZheng Lu, Zhu Zhu, Wei Cai, XinPeng Ning, ShengLong Li, TianYu Qi, JiaKai Pi, SuiZhen Lin, GuangMei Yan, YiJun Huang, Wei Yin
Publikováno v:
ACS Chemical Neuroscience. 13:2110-2121
As one of the key injury incidents, tissue acidosis in the brain occurs very quickly within several minutes upon the onset of ischemic stroke. Glutamate, an excitatory amino acid inducing neuronal excitotoxicity, has been reported to trigger the decr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a480b7db0f9f0a5a5c42aa95fc9ec1d8
https://doi.org/10.1021/acschemneuro.2c00119
https://doi.org/10.1021/acschemneuro.2c00119
Autor:
Yijun Huang, Pei Zhang, Zhong-Wei Tang, David Neil Cooper, Fuyu Liu, Min Yan, Wei Yin, Zhi-Bing Yuan, Guangmei Yan, Chunxue Guo, Yuan Li, Suizhen Lin, Wenbo Zhu, Longxiang Sheng, Qiye Li, Xiaoyu Zhan, Jian Wang, Jiesi Chen, Guojie Zhang, Youqiong Wang, Huanming Yang, Gang Xu, Jingxia Zhang, Bitao Qiu, Bingzheng Lu, Yixing Gao, Yuqi Gao
Publikováno v:
Zoological Research
Zoological Research, Vol 41, Iss 1, Pp 3-19 (2020)
Zhang, P, Chen, J-S, Li, Q-Y, Sheng, L-X, Gao, Y-X, Lu, B-Z, Zhu, W-B, Zhan, X-Y, Li, Y, Yuan, Z-B, Xu, G, Qiu, B-T, Yan, M, Guo, C-X, Wang, Y-Q, Huang, Y-J, Zhang, J-X, Liu, F-Y, Tang, Z-W, Lin, S-Z, Cooper, D N, Yang, H-M, Wang, J, Gao, Y-Q, Yin, W, Zhang, G-J & Yan, G-M 2019, ' Neuroprotectants attenuate hypobaric hypoxia-induced brain injuries in cynomolgus monkeys ', Zoological research, vol. 41, no. 1, pp. 3-19 . https://doi.org/10.24272/j.issn.2095-8137.2020.012
Zoological Research, Vol 41, Iss 1, Pp 3-19 (2020)
Zhang, P, Chen, J-S, Li, Q-Y, Sheng, L-X, Gao, Y-X, Lu, B-Z, Zhu, W-B, Zhan, X-Y, Li, Y, Yuan, Z-B, Xu, G, Qiu, B-T, Yan, M, Guo, C-X, Wang, Y-Q, Huang, Y-J, Zhang, J-X, Liu, F-Y, Tang, Z-W, Lin, S-Z, Cooper, D N, Yang, H-M, Wang, J, Gao, Y-Q, Yin, W, Zhang, G-J & Yan, G-M 2019, ' Neuroprotectants attenuate hypobaric hypoxia-induced brain injuries in cynomolgus monkeys ', Zoological research, vol. 41, no. 1, pp. 3-19 . https://doi.org/10.24272/j.issn.2095-8137.2020.012
Hypobaric hypoxia (HH) exposure can cause serious brain injury as well as life-threatening cerebral edema in severe cases. Previous studies on the mechanisms of HH-induced brain injury have been conducted primarily using non-primate animal models tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82c5fa469c4ec933d83d10f1ec12a441
https://doi.org/10.24272/j.issn.2095-8137.2020.012
https://doi.org/10.24272/j.issn.2095-8137.2020.012
Autor:
Zhijie Chen, Jialuo Mai, Shuxin Sun, Jiayv Gu, Yuan Lin, Xincheng Liu, Dongdong Xue, Wenfeng Liu, Zhongping Chen, Yonggao Mou, Ke Sai, Longxiang Sheng, Fan Xing, Ji Zhang, Ying Ouyang, Wenbo Zhu, Wanjun Lu, Bingzheng Lu, Guangmei Yan
Publikováno v:
Cell Death and Disease, Vol 10, Iss 5, Pp 1-16 (2019)
Cell Death & Disease
Cell Death & Disease
Given that glioma stem cells (GSCs) play a critical role in the initiation and chemoresistance in glioblastoma multiforme (GBM), targeting GSCs is an attractive strategy to treat GBM. Utilizing an anti-cancer compound library, we identified R406, the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::833918c38d6da0eed1eecd35ca369b16
http://link.springer.com/article/10.1038/s41419-019-1587-0
http://link.springer.com/article/10.1038/s41419-019-1587-0