Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Bingyan J. Wang"'
Autor:
Megan M. Monsanto, Bingyan J. Wang, Zach R. Ehrenberg, Oscar Echeagaray, Kevin S. White, Roberto Alvarez, Kristina Fisher, Sharon Sengphanith, Alvin Muliono, Natalie A. Gude, Mark A. Sussman
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-20 (2020)
Despite recent progress to advance cardiac cell-based therapy for patients, heart failure mortality rivals most cancers. Here, the authors describe an approach to control and pattern 3 distinct human cardiac cell populations to promote superior repai
Externí odkaz:
https://doaj.org/article/d8965aba695e4b73854957d83edbac8e
Autor:
Bingyan J. Wang, Roberto Alvarez Jr, Alvin Muliono, Sharon Sengphanith, Megan M. Monsanto, Joi Weeks, Roberto Sacripanti, Mark A. Sussman
Publikováno v:
Stem Cells Translational Medicine, Vol 9, Iss 5, Pp 620-635 (2020)
Abstract Cardiac interstitial cells (CICs) perform essential roles in myocardial biology through preservation of homeostasis as well as response to injury or stress. Studies of murine CIC biology reveal remarkable plasticity in terms of transcription
Externí odkaz:
https://doaj.org/article/6296ffd372194ebf9ccec5863887ba70
Autor:
David E. Ebeid, Fareheh Firouzi, Carolina Y. Esquer, Julian M. Navarrete, Bingyan J. Wang, Natalie A. Gude, Mark A. Sussman
Publikováno v:
Cells, Vol 9, Iss 9, p 2001 (2020)
Enhancing cardiomyocyte survival is crucial to blunt deterioration of myocardial structure and function following pathological damage. PIM1 (Proviral Insertion site in Murine leukemia virus (PIM) kinase 1) is a cardioprotective serine threonine kinas
Externí odkaz:
https://doaj.org/article/7f94c897a08a4ad782a530b58c5a5d0d
Autor:
Veronica Sacchi, Bingyan J. Wang, Dieter Kubli, Alexander S. Martinez, Jung‐Kang Jin, Roberto Alvarez, Nirmala Hariharan, Christopher Glembotski, Takafumi Uchida, James S. Malter, Yijun Yang, Polina Gross, Chen Zhang, Steven Houser, Marcello Rota, Mark A. Sussman
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 6, Iss 10 (2017)
BackgroundAberrant Ca2+ handling is a prominent feature of heart failure. Elucidation of the molecular mechanisms responsible for aberrant Ca2+ handling is essential for the development of strategies to blunt pathological changes in calcium dynamics.
Externí odkaz:
https://doaj.org/article/6a2db19b32c94847a8eac79c834c6bb5
Autor:
Iwanari Kawamura, Vivek Y. Reddy, Carlos G. Santos-Gallego, Bingyan J. Wang, Hina W. Chaudhry, Eric D. Buck, George Mavroudis, Samantha Jerrell, Christopher W. Schneider, Molly Speltz, Srinivas R. Dukkipati, Jacob S. Koruth
Publikováno v:
Circulation. Arrhythmia and electrophysiology.
Background: Pulsed field ablation (PFA) has recently been shown to penetrate ischemic scar, but details on its efficacy, risk of arrhythmias, and imaging insights are lacking. In a porcine model of myocardial scar, we studied the ability of ventricul
Autor:
Iwanari Kawamura, Vivek Y. Reddy, Bingyan J. Wang, Srinivas R. Dukkipati, Hina W. Chaudhry, Carlos G Santos-Gallego, Jacob S. Koruth
Publikováno v:
Circulation. Arrhythmia and electrophysiology. 15(9)
Background: Our understanding of catheter-based pulsed field ablation (PFA) of the ventricular myocardium is limited. We conducted a series of exploratory evaluations of ventricular PFA in swine ventricles. Methods: A focal lattice-tip catheter was u
Autor:
Bingyan J. Wang, Sangeetha Vadakke-Madathil, Lori B. Croft, Rachel I. Brody, Hina W. Chaudhry
Publikováno v:
JACC: Basic to Translational Science
Autor:
Sharon Sengphanith, Megan M. Monsanto, Roberto Sacripanti, Roberto Alvarez, Alvin Muliono, Mark A. Sussman, Joi Weeks, Bingyan J. Wang
Publikováno v:
Stem Cells Translational Medicine
Stem Cells Translational Medicine, Vol 9, Iss 5, Pp 620-635 (2020)
Stem cells translational medicine, vol 9, iss 5
Stem Cells Translational Medicine, Vol 9, Iss 5, Pp 620-635 (2020)
Stem cells translational medicine, vol 9, iss 5
Cardiac interstitial cells (CICs) perform essential roles in myocardial biology through preservation of homeostasis as well as response to injury or stress. Studies of murine CIC biology reveal remarkable plasticity in terms of transcriptional reprog
Autor:
Monica Chavarria, Roberto Alvarez, Pearl Quijada, Kathleen M. Broughton, Megan M. Monsanto, Thi Ho, Mark A. Sussman, Maya Shaitrit, David E. Ebeid, Natalie Navarrete, Bingyan J. Wang, Maryam Moshref, Daniele Avitabile, Barbara A. Bailey, Fareheh Firouzi, Natalie Gude, Sailay Siddiqi
Publikováno v:
Journal of Molecular and Cellular Cardiology. 127:154-164
Rationale Understanding and manipulating the cardiomyocyte cell cycle has been the focus of decades of research, however the ultimate goal of activating mitotic activity in adult mammalian cardiomyocytes remains elusive and controversial. The relentl
Autor:
Robert M. Adamson, Mark A. Sussman, Dieter A Kubli, Fareheh Firouzi, Bingyan J. Wang, Megan M. Monsanto, Farid G. Khalafalla, Åsa B. Gustafsson, Kelli Korski, Walter P. Dembitsky, Taeyong Kim, Oscar Echeagaray
Publikováno v:
Stem Cells. 37:555-567
Senescence-associated dysfunction deleteriously affects biological activities of human c-Kit+ cardiac progenitor cells (hCPCs), particularly under conditions of in vitro culture. In comparison, preservation of self-renewal and decreases in mitochondr