Zobrazeno 1 - 10
of 312
pro vyhledávání: '"Bingya Liu"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Improvement in the survival rate of gastric cancer, a prevalent global malignancy and the leading cause of cancer-related mortality calls for more avenues in molecular therapy. This work aims to comprehend drug resistance and explore multipl
Externí odkaz:
https://doaj.org/article/aa1923011de640afa83c9d1cdc3bc0c4
Autor:
Nan Zhu, Yupeng Zhao, Wenjing Yan, Lan Wei, Qingqing Sang, Jianfang Li, Bingya Liu, Beiqin Yu
Publikováno v:
Cancer Cell International, Vol 24, Iss 1, Pp 1-16 (2024)
Abstract Background Accumulating evidences indicate that the specific alternative splicing (AS) events are linked to the occurrence and prognosis of gastric cancer (GC). Nevertheless, the impact of AS is still unclear and needed to further elucidatio
Externí odkaz:
https://doaj.org/article/136bc10602ae4687a9dd3df1f4bc7d64
PHD finger protein 10 promotes cell proliferation by regulating CD44 transcription in gastric cancer
Publikováno v:
Heliyon, Vol 10, Iss 7, Pp e29109- (2024)
PHD finger protein 10 (PHF10) plays an important role in the tumorigenesis of gastric cancer (GC). However, clinical significance and underlying molecular mechanisms about PHF10 is unclear. In the article, it suggested that PHF10 involved in tumor pr
Externí odkaz:
https://doaj.org/article/62478c24c6014d32b9e97e335d733606
Autor:
Fangyuan Li, Junxian Yu, Tao Pan, Haoran Feng, Jianfang Li, Beiqin Yu, Zhiyuan Fan, Qingqing Sang, Mengdi Chen, Mingde Zang, Junyi Hou, Xiongyan Wu, Yingyan Yu, Yuan‐Yuan Li, Chao Yan, Zhenggang Zhu, Liping Su, Bingya Liu
Publikováno v:
Advanced Science, Vol 10, Iss 34, Pp n/a-n/a (2023)
Abstract Erlotinib, an EGFR tyrosine kinase inhibitor, is used for treating patients with cancer exhibiting EGFR overexpression or mutation. However, the response rate of erlotinib is low among patients with gastric cancer (GC). The findings of this
Externí odkaz:
https://doaj.org/article/a52d13ec381e41e3b9daef4653ccf9a8
Autor:
Lizhong Yao, Junyi Hou, Xiongyan Wu, Yifan Lu, Zhijian Jin, Zhenjia Yu, Beiqin Yu, Jianfang Li, Zhongyin Yang, Chen Li, Min Yan, Zhenggang Zhu, Bingya Liu, Chao Yan, Liping Su
Publikováno v:
Redox Biology, Vol 67, Iss , Pp 102923- (2023)
As the predominant immunosuppressive component within the tumor microenvironment (TME), cancer-associated fibroblasts (CAFs) inhibit Natural Killer cell (NK cell) activity to promote tumor progression and immune escape; however, the mechanisms of cro
Externí odkaz:
https://doaj.org/article/1a8ad35e533843c1aa456774f9853db2
Publikováno v:
Genes and Diseases, Vol 9, Iss 6, Pp 1427-1430 (2022)
Externí odkaz:
https://doaj.org/article/07bf0b4008ab4b769e3eb56b04f2e4dd
Autor:
Junxian Yu, Haoran Feng, Qingqing Sang, Fangyuan Li, Mengdi Chen, Beiqin Yu, Zhuoqing Xu, Tao Pan, Xiongyan Wu, Junyi Hou, Zhenggang Zhu, Chao Yan, Liping Su, Jianfang Li, Bingya Liu
Publikováno v:
EBioMedicine, Vol 89, Iss , Pp 104451- (2023)
Summary: Background: Vacuolar protein sorting-associated protein 35 (VPS35) is a core component of the retromer complex which mediates intracellular protein transport. It is well known that dysfunctional VPS35 functions in the accumulation of pathoge
Externí odkaz:
https://doaj.org/article/94f42f705cd9499ca81f0c20c0b13e5f
Autor:
Beiqin Yu, Wentao Dai, Li Pang, Qingqing Sang, Fangyuan Li, Junxian Yu, Haoran Feng, Jianfang Li, Junyi Hou, Chao Yan, Liping Su, Zhenggang Zhu, Yuan-Yuan Li, Bingya Liu
Publikováno v:
Molecular Medicine, Vol 28, Iss 1, Pp 1-14 (2022)
Abstract Background The mechanisms of Gastric cancer (GC) initiation and progression are complicated, at least partly owing to the dynamic changes of gene regulation during carcinogenesis. Thus, investigations on the changes in regulatory networks ca
Externí odkaz:
https://doaj.org/article/1ecbed3c249747d7862af11263ce2f50
Autor:
Zhiyuan Fan, Beiqin Yu, Tao Pan, Fangyuan Li, Jianfang Li, Junyi Hou, Wentao Liu, Liping Su, Zhenggang Zhu, Chao Yan, Bingya Liu
Publikováno v:
Translational Oncology, Vol 27, Iss , Pp 101577- (2023)
Background: Adjuvant chemotherapy (ACT) with 5-FU alone or 5-FU plus platinum after curative surgery improves the prognosis of pStage II-III gastric cancer (GC). However, only a subset of patients benefits from adjuvant platinum. To avoid the side ef
Externí odkaz:
https://doaj.org/article/d039f524c0d849e1b036c0323bb01681
Autor:
Qingqing Sang, Wentao Dai, Junxian Yu, Yunqin Chen, Zhiyuan Fan, Jixiang Liu, Fangyuan Li, Jianfang Li, Xiongyan Wu, Junyi Hou, Beiqin Yu, Haoran Feng, Zheng-Gang Zhu, Liping Su, Yuan-Yuan Li, Bingya Liu
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Increasing evidence has elucidated that the tumor microenvironment (TME) shows a strong association with tumor progression and therapeutic outcome. We comprehensively estimated the TME infiltration patterns of 111 gastric cancer (GC) and 21 normal st
Externí odkaz:
https://doaj.org/article/cb1a0744b0bf44e39ad67157142b0aa4