Zobrazeno 1 - 10
of 96
pro vyhledávání: '"Bingwei Sun"'
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-17 (2024)
Abstract As frontline cells, the precise recruitment of neutrophils is crucial for resolving inflammation and maintaining the homeostasis of the organism. Increasing evidence suggests the pivotal role of neutrophil chemotaxis in cancer progression an
Externí odkaz:
https://doaj.org/article/4091c30892d94779817ce71847861a89
Autor:
Yanzhen Yu, Hangfei Jin, Linbin Li, Xin Zhang, Chunfang Zheng, Xi Gao, Yunxi Yang, Bingwei Sun
Publikováno v:
Journal of Nanobiotechnology, Vol 21, Iss 1, Pp 1-16 (2023)
Abstract Chronic diabetic wounds are primarily caused by infection, inflammation, and angiogenesis-related disorders. An ideal approach for treating chronic diabetic wounds is by combining anti-infection strategies, immune microenvironment regulation
Externí odkaz:
https://doaj.org/article/093b6abbc510493aa52c7541c0242a35
Publikováno v:
Cell Transplantation, Vol 33 (2024)
The management of granulocytopenia-associated infections is challenging, and a high mortality rate is associated with traditional supportive therapies. Neutrophils—the primary defenders of the human immune system—have potent bactericidal capabili
Externí odkaz:
https://doaj.org/article/fb71aebc625f4b67bd22ceaf5d49a3d9
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract Low-density neutrophils (LDNs) have been described in tumors and various autoimmune diseases, where they exhibit immune dysfunction and alter disease progression. Nevertheless, LDNs have been rarely reported in sepsis. We studied sepsis pati
Externí odkaz:
https://doaj.org/article/5fb1e0aa6f9045159049ce76c82e3fcf
Autor:
Yi Chen, Jiamin Huang, Zaiwen Guo, Zhechen Zhu, Yiming Shao, Linbin Li, Yunxi Yang, Yanzhen Yu, Lu Liu, Bingwei Sun
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
The function and heterogeneity of neutrophils in neonatal umbilical cord blood (UCB) have not been characterized. In this study, we analyzed the neutrophils in UCB and healthy adults using single-cell RNA sequencing analysis for the first time. We fo
Externí odkaz:
https://doaj.org/article/b1306a567fbf4b3fb64191a6d090c549
Publikováno v:
Critical Care, Vol 25, Iss 1, Pp 1-16 (2021)
Abstract Background Although the immune function of neutrophils in sepsis has been well described, the heterogeneity of neutrophils remains unclear during the process of sepsis. Methods In this study, we used a mouse CLP model to simulate the clinica
Externí odkaz:
https://doaj.org/article/89f8434d7e8f4cab93c2db62826d6e81
Autor:
Yunxi Yang, Lu Liu, Zaiwen Guo, Jiamin Huang, Linbin Li, Yiming Shao, Mingming Song, Aixiang Yang, Bingwei Sun
Publikováno v:
Clinical & Translational Immunology, Vol 10, Iss 8, Pp n/a-n/a (2021)
Abstract Objectives To evaluate the value of chemotactic function of neutrophils in patients with severe infections. Methods A computer vision‐based cellular chemotaxis analysis platform was established for the dynamic assessment of neutrophil chem
Externí odkaz:
https://doaj.org/article/bfcb788c45a54a05ba9caba9cbf09056
Publikováno v:
Burns & Trauma, Vol 2, Iss 3, Pp 114-120 (2014)
Neutrophil and platelet are essential arms of the innate immune response. In sepsis, platelet abnormal activation as well as neutrophil paralysis are well recognized. For platelet, it is characterized by the contribution to disseminated intravascular
Externí odkaz:
https://doaj.org/article/e7a28bf6c940407abbb2a4680aad1f43
Publikováno v:
International Journal of Biological Sciences, Vol 4, Iss 5, Pp 270-278 (2008)
Objective: To investigate the effects and potential mechanisms of preconditioning of tricarbonyldichlororuthenium (III) dimer (CORM-2)-liberated CO on LPS-induced activation of endothelial cells (HUVEC). Methods: HUVEC were pretreated with CORM-2 at
Externí odkaz:
https://doaj.org/article/18cc59e033d045d588e028e86bd37b9e
Publikováno v:
International Journal of Biological Sciences, Vol 4, Iss 3, Pp 176-183 (2008)
Objective: To determine whether the CO-releasing molecule -liberated CO attenuates infiltration of leukocytes in the renal tissue of thermally injured mice. Materials and methods: Twenty-eight mice were assigned to four groups. Mice in sham group (n=
Externí odkaz:
https://doaj.org/article/bec6403bcc8a4f37b43fc2ecd4d73932