Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Bingni Liu"'
Autor:
Chuanming Zhang, Jincan Kang, Wen Dai, Yanbo Peng, Yiling Zhao, Xiaoang Yang, Bingni Liu, Hongping Zhu
Publikováno v:
Heliyon, Vol 10, Iss 23, Pp e39723- (2024)
The pathway for producing 1,3-propanediol (1,3-PDO) from methyl 3-hydroxypropionate (3-HPM) has great application potential. However, the reaction is sensitive to temperature and results in reduced product selectivity at high temperatures. This study
Externí odkaz:
https://doaj.org/article/41a2a88a09ef44c6842cbb1184df09b6
Publikováno v:
Zhongguo aizheng zazhi, Vol 33, Iss 3, Pp 260-266 (2023)
Background and purpose: The value of Vesical Imaging-Reporting and Data System (VI-RADS) based on multiparametric magnetic resonance imaging (MRI) in the preoperative assessment of bladder cancer muscle-invasive is increasingly recognized. However, t
Externí odkaz:
https://doaj.org/article/45b29d21389a4f34ba81b66a497137af
Publikováno v:
Zhongguo aizheng zazhi, Vol 32, Iss 2, Pp 134-141 (2022)
Background and purpose: Androgen deprivation therapy (ADT) is a key primary treatment for prostate cancer. However, there is still a lack of direct and accurate assessment method for the changes in the lesions after ADT treatment. The aim of this stu
Externí odkaz:
https://doaj.org/article/6e5c9c12d2474e1b8b53f9646ae2c387
Autor:
Bingni Liu
Publikováno v:
Journal of Politics and Law. 16:45
Whether the pre-litigation procedure of shareholder representative is effective is one of the important issues about the functioning of shareholder representative litigation. In judicial practice in China, the identification of the subject of shareho
Publikováno v:
Journal of Heterocyclic Chemistry. 53:1259-1263
An efficient and mild synthetic method was developed for tofacitinib citrate from 3-amino-4-methylpyridine and 4-chloro-7H-pyrrolo[2,3-d]pyrimidine. The related reactions were systematically optimized. Sodium hydride instead of potassium tert-butoxid
Autor:
Jianwu Wang, Guilong Zhao, Wei Qunchao, Yongheng Shi, Lingyu Zhang, Weiren Xu, Bingni Liu, Huaqiang Xu, Lida Tang, Yu-Li Wang
Publikováno v:
Medicinal Chemistry. 10:304-317
Systematic mono-deoxylation of the four hydroxyl groups in the glucose moiety in dapagliflozin led to the discovery of 6-deoxydapagliflozin 1 as a more active sodium-dependent glucose cotransporter 2 (SGLT2) inhibitor (IC50 = 0.67 nM against human SG
Autor:
Yongheng Shi, Bingni Liu, Li-Da Tang, Weiren Xu, Kong Weiling, Wei Qunchao, Guilong Zhao, Hua-Qiang Xu
Publikováno v:
Monatshefte für Chemie - Chemical Monthly. 144:1903-1910
A facile synthesis of a potent SGLT2 inhibitor, 6-deoxydapagliflozin, from methyl 2,3,4-tri-O-benzyl-6-deoxy-6-iodo-α-d-glucopyranoside in six steps with an overall yield of 50 % is described. The key steps were the reductive deiodination of the sta
Autor:
Wei Qunchao, Bingni Liu, Guilong Zhao, Weiren Xu, Lida Tang, Yongheng Shi, Huaqiang Xu, Kong Weiling
Publikováno v:
ChemInform. 45
Publikováno v:
Bioorganicmedicinal chemistry letters. 24(4)
A series of novel pazopanib derivatives, 7a–m, were designed and synthesized by modification of terminal benzene and indazole rings in pazopanib. The structures of all the synthesized compounds were confirmed by 1H NMR and MS. Their inhibitory acti
Autor:
Dong-Qing Wei, Kuo-Chen Chou, Hui Gao, Yun Li, Bingni Liu, Changjiang Huang, Wei-Na Gao, Deng-Ke Liu, Wei-Ren Xu, Hai-Feng Chen
Publikováno v:
Medicinal chemistry (Shariqah (United Arab Emirates)). 3(6)
A three dimensional Quantitative Structure Activity Relationship (3D-QSAR) model for a series of (S)-3-Aryl-5-substituted oxazolidinones was developed to gain insights into the design for potential new antibacterial agents. It was found that the Comp