Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Bingling Luo"'
Autor:
Bingling Luo, Jiankang Wang, Xiaobing Li, Wenhua Lu, Jing Yang, Yumin Hu, Peng Huang, Shijun Wen
Publikováno v:
Molecules, Vol 22, Iss 6, p 773 (2017)
In our current work, acetyl chloride-mediated synthesis of phenethyl isothiocyanate (PEITC) derivatives proves to be convenient and provides the expected products at good to excellent yields. Biological evaluation and structure-activity relationship
Externí odkaz:
https://doaj.org/article/53f88781b50b4cd5b5eb1f766d89e1f6
Autor:
Zhirong Guo, Yameng Sun, Liyun Liang, Wenhua Lu, Bingling Luo, Zhouming Wu, Bitao Huo, Yumin Hu, Peng Huang, Qiang Wu, Shijun Wen
Publikováno v:
Journal of Medicinal Chemistry. 65:6573-6592
EZH2 inhibitors that prevent trimethylation of histone lysine 27 (H3K27) are often limited to the treatment of a subset of hematological malignancies. In most solid tumors, EZH2 inhibitors induce reciprocal H3K27 acetylation that subsequently results
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85f3375f906e5d8c06be47c62ece7fa1
https://doi.org/10.1021/acs.jmedchem.1c01876
https://doi.org/10.1021/acs.jmedchem.1c01876
Autor:
Tian Tian, Shengyi Zhang, Bingling Luo, Feng Yin, Wenhua Lu, Yiqing Li, Kezhi Huang, Qiao Liu, Peng Huang, G Garcia-Manero, Shijun Wen, Yumin Hu
Publikováno v:
Journal of Medicinal Chemistry. 65:3597-3605
Internal tandem duplication in the FLT3 receptor tyrosine kinase (FLT3/ITD mutation) occurs in approximately 25% of acute myeloid leukemia (AML) patients. To specifically target this driver mutation in AML, we assessed and compared the cell-based cyt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c02c33dfa5da934b874181fc1427388
https://doi.org/10.1021/acs.jmedchem.1c02079
https://doi.org/10.1021/acs.jmedchem.1c02079
Autor:
Hui Peng, Qian Liu, Yameng Sun, Bingling Luo, Tianyian Yu, Peng Huang, Daqian Zhu, Shijun Wen
Publikováno v:
Organic Chemistry Frontiers. 9:1137-1142
Linear diaryliodoniums often undergo only single arylation and leave equivalent aryl iodide as waste.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::42b6410565ef0c1f0345d543082c0721
https://doi.org/10.1039/d1qo01463c
https://doi.org/10.1039/d1qo01463c
Autor:
Qingbin Cui, Wenwen Ding, Panpan Liu, Bingling Luo, Jing Yang, Wenhua Lu, Yumin Hu, Peng Huang, Shijun Wen
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 20; Pages: 12169
Reactive oxygen species (ROS) homeostasis and mitochondrial metabolism are critical for the survival of cancer cells, including cancer stem cells (CSCs), which often cause drug resistance and cancer relapse. Auranofin is a mono-gold anti-rheumatic dr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15f1dc9635e0701b3e15671ab74e94ff
https://pubmed.ncbi.nlm.nih.gov/36293028
https://pubmed.ncbi.nlm.nih.gov/36293028
Autor:
Yumin Hu, Shijun Wen, Peng Huang, Tiantian Yu, Daqian Zhu, Yameng Sun, Bingling Luo, Yun Wang, Hui Peng, Zhouming Wu
Publikováno v:
Green Chemistry. 23:1972-1977
Polycyclic aromatic hydrocarbons (PAHs) are of increasing importance in the advanced material field. Cyclic diaryliodonium salts are non-toxic and environmentally benign arylating reagents. Here, we describe an alkylamine-mediated free radical intram
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ef0eeca82053104ac0416a97cfc2b8da
https://doi.org/10.1039/d0gc04183a
https://doi.org/10.1039/d0gc04183a
Publikováno v:
Advanced Synthesis & Catalysis. 363:222-226
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7dc734b569ea3a10372c2fe61c97740c
https://doi.org/10.1002/adsc.202001080
https://doi.org/10.1002/adsc.202001080
Publikováno v:
Investigational New Drugs. 38:755-764
Glioblastoma multiforme (GBM) is the most common malignant tumor of the central nervous system (CNS). Effective treatments remain limited. Therefore, novel chemotherapy drugs with high efficiency and few adverse effects are urgently needed. Histone d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c47d15bf6f8adb86ed7a79c665cc92cb
https://doi.org/10.1007/s10637-019-00821-4
https://doi.org/10.1007/s10637-019-00821-4
Publikováno v:
European Journal of Organic Chemistry. 2019:4566-4571
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::74f00805dede1ac90097ae9479a53d4c
https://doi.org/10.1002/ejoc.201900745
https://doi.org/10.1002/ejoc.201900745
Publikováno v:
RSC Advances. 9:33170-33179
Polycyclic heteroarenes are important scaffolds in the construction of pharmaceuticals. We have previously developed a series of novel heterocyclic iodoniums. In our current work, these unique iodoniums were employed to construct various complex poly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71c774f0f3d60ebb3cd27f157089d7de
https://doi.org/10.1039/c9ra07288h
https://doi.org/10.1039/c9ra07288h