Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Binghua Hao"'
Autor:
Hassan Badrane, Shaoji Cheng, Christopher L. Dupont, Binghua Hao, Eileen Driscoll, Kristin Morder, Guojun Liu, Anthony Newbrough, Giuseppe Fleres, Drishti Kaul, Josh L. Espinoza, Cornelius J. Clancy, M. Hong Nguyen
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract The longstanding model is that most bloodstream infections (BSIs) are caused by a single organism. We perform whole genome sequencing of five-to-ten strains from blood culture (BC) bottles in each of ten patients with Candida glabrata BSI. W
Externí odkaz:
https://doaj.org/article/3ef397b1e57241ecb52e5dbd9f8dc58a
Autor:
Shaoji Cheng, Giuseppe Fleres, Liang Chen, Guojun Liu, Binghua Hao, Anthony Newbrough, Eileen Driscoll, Ryan K. Shields, Kevin M. Squires, Ting-yu Chu, Barry N. Kreiswirth, M. Hong Nguyen, Cornelius J. Clancy
Publikováno v:
mBio, Vol 13, Iss 6 (2022)
ABSTRACT It is unknown whether bacterial bloodstream infections (BSIs) are commonly caused by single organisms or mixed microbial populations. We hypothesized that contemporaneous carbapenem-resistant Klebsiella pneumoniae (CRKP) strains from blood c
Externí odkaz:
https://doaj.org/article/8bba3d1e7b134705bbfe1806872b7622
Autor:
Anthony Newbrough, Giuseppe Fleres, Binghua Hao, Liang Chen, Ryan K Shields, Cornelius J Clancy, Minh-Hong Nguyen
Publikováno v:
Open Forum Infectious Diseases. 9
Background Antibiotic resistant ENT are a growing threat worldwide. QPX is an ultra-broad-spectrum β-lactamase inhibitor (BLI) with potent inhibition of classes A and D, and many metallo-β-lactamases, which has potential to fill the void of current
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::60380c6c6667403065d3f778b75c53dd
https://doi.org/10.1093/ofid/ofac492.1367
https://doi.org/10.1093/ofid/ofac492.1367
Autor:
Giuseppe Fleres, Shaoji Cheng, Liang Chen, Guojun Liu, Binghua Hao, Anthony Newbrough, Ryan K Shields, Barry N Kreiswirth, Minh-Hong Nguyen, Cornelius J Clancy
Publikováno v:
Open Forum Infectious Diseases. 9
Background The longstanding paradigm is that almost all bloodstream infections (BSIs) stem from a single, clonal organism. We hypothesized that carbapenem resistant K. pneumoniae (CRKP) from individual patients (pts) with BSIs are genetically diverse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ee4b1a61ab75494fe95cc102f0db76d9
https://doi.org/10.1093/ofid/ofac492.1467
https://doi.org/10.1093/ofid/ofac492.1467
Autor:
Giuseppe Fleres, Anthony Newbrough, Binghua Hao, Liang Chen, Ryan K Shields, Cornelius J Clancy, Minh-Hong Nguyen
Publikováno v:
Open Forum Infectious Diseases. 9
Background Pseudomonas aeruginosa (PA) is an important pathogen notorious for antibiotic resistance. Xeruborbactam (QPX) is a potent ultra-broad-spectrum boronic acid β-lactam inhibitor (BLI) that, in combination with selected BL antibiotics, has ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e4d89bac87b3e95956d1252520a9613e
https://doi.org/10.1093/ofid/ofac492.1366
https://doi.org/10.1093/ofid/ofac492.1366
Autor:
Cornelius J. Clancy, Binghua Hao, M. Hong Nguyen, A. William Pasculle, Shaoji Cheng, Barry N. Kreiswirth, Ellen G Kline, Jonathan Sun, Ryan K. Shields, Liang Chen
Publikováno v:
Clin Infect Dis
Background Multidrug-resistant Enterobacterales (MDR-E), including carbapenem-resistant and third-generation cephalosporin-resistant Enterobacterales (CRE, CefR-E), are major pathogens following solid organ transplantation (SOT). Methods We prospecti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fe6725dfa317370f5c274dd39e44eec
https://doi.org/10.1093/cid/ciab427
https://doi.org/10.1093/cid/ciab427
Autor:
Shaoji Cheng, Guojun Liu, Binghua Hao, Anthony Newbrough, Cornelius J Clancy, Minh-Hong Nguyen
Publikováno v:
Open Forum Infectious Diseases. 8:S594-S594
Background Hypermutator (HM) bacteria exhibit high spontaneous mutation rates due to DNA mismatch repair (MMR) gene mutations, which may facilitate antibiotic resistance. HM is best described for chronic infections or colonization, in particular with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7af1ec965c1b508885117c10b7677d29
https://doi.org/10.1093/ofid/ofab466.1201
https://doi.org/10.1093/ofid/ofab466.1201
Publikováno v:
Proceedings of the 3rd International Conference on Mechatronics Engineering and Information Technology (ICMEIT 2019).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d093beb8b450e206b4f5de3510c74821
https://doi.org/10.2991/icmeit-19.2019.55
https://doi.org/10.2991/icmeit-19.2019.55
Autor:
M. Hong Nguyen, Ghady Haidar, Brian A. Potoski, Barry N. Kreiswirth, Liang Chen, Binghua Hao, Yohei Doi, Cornelius J. Clancy, Ryan K. Shields, Ellen G. Press
Publikováno v:
Clinical Infectious Diseases. 63:1615-1618
Thirty-seven carbapenem-resistant Enterobacteriaceae (CRE)-infected patients were treated with ceftazidime-avibactam. Clinical success and survival rates at 30 days were 59% (22/37) and 76% (28/37), respectively. In 23% (5/22) of clinical successes,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cf4d07c4fd48b5003d2a676e5e96a6b9
https://doi.org/10.1093/cid/ciw636
https://doi.org/10.1093/cid/ciw636
Publikováno v:
Antimicrobial Agents and Chemotherapy. 62
We tested ceftazidime-avibactam and colistin against 24 carbapenem-resistant Enterobacteriaceae (CRE) isolates by time-kill studies. Ceftazidime-avibactam at 0.25×, 1×, and 4× the MIC was bactericidal against 8%, 21%, and 88% of the isolates, resp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5730601773244f53c99a2c2b845eee6
https://doi.org/10.1128/aac.01018-18
https://doi.org/10.1128/aac.01018-18