Zobrazeno 1 - 10
of 529
pro vyhledávání: '"Binghe Wang"'
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 38, Iss 1 (2023)
Conjugation of drugs with biotin is a widely studied strategy for targeted drug delivery. The structure–activity relationship (SAR) studies through H3-biotin competition experiments conclude with the presence of a free carboxylic acid being essenti
Externí odkaz:
https://doaj.org/article/b9a9f53c77814a6b840b49a26d930222
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 13, Iss 5, Pp 1990-2016 (2023)
Click chemistry has been proven to be very useful in drug delivery. Due to the availability of a large number of click reactions with a various characteristics, selection of appropriate chemistry for a given application is often not a trivial task. T
Externí odkaz:
https://doaj.org/article/159e168f4a6245538a5e6628789ce0c4
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 37, Iss 1, Pp 2370-2381 (2022)
Overexpression of ubiquitin ligase MDM2 causes depletion of the p53 tumour-suppressor and thus leads to cancer progression. In recent years, anthraquinone analogs have received significant attention due to their ability to downregulate MDM2, thereby
Externí odkaz:
https://doaj.org/article/1b1c5832c6254715b94a2b961073e185
Autor:
Liehui ZHANG, Yu XIONG, Yulong ZHAO, Hongming TANG, Jingjing GUO, Chunsheng JIA, Qiang LEI, Binghe WANG
Publikováno v:
Petroleum Exploration and Development, Vol 49, Iss 1, Pp 144-155 (2022)
Based on the study of damage mechanisms of generalized water blocking and related water-blocking removal methods, the drying agents for enhancing tight gas reservoir recovery were developed, and the basic properties, injection mode and drying effect
Externí odkaz:
https://doaj.org/article/9535172493c943e396af6745afcb79b3
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 11, Iss 6, Pp 1434-1445 (2021)
Nature has endowed gaseous molecules such as O2, CO2, CO, NO, H2S, and N2 with critical and diverse roles in sustaining life, from supplying energy needed to power life and building blocks for life's physical structure to mediating and coordinating c
Externí odkaz:
https://doaj.org/article/a0c158f7ba8a44269dc5b79ed322d66c
Autor:
Dominik Bakalarz, Marcin Surmiak, Xiaoxiao Yang, Dagmara Wójcik, Edyta Korbut, Zbigniew Śliwowski, Grzegorz Ginter, Grzegorz Buszewicz, Tomasz Brzozowski, Jakub Cieszkowski, Urszula Głowacka, Katarzyna Magierowska, Zhixiang Pan, Binghe Wang, Marcin Magierowski
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 11, Iss 2, Pp 456-475 (2021)
Metal-based carbon monoxide (CO)-releasing molecules have been shown to exert anti-inflammatory and anti-oxidative properties maintaining gastric mucosal integrity. We are interested in further development of metal-free CO-based therapeutics for oral
Externí odkaz:
https://doaj.org/article/84974910c66e4a31b9e63f91767064e2
Autor:
Jalisa H. Ferguson, Zeus De Los Santos, Saroja N. Devi, Stefan Kaluz, Erwin G. Van Meir, Sarah K. Zingales, Binghe Wang
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 32, Iss 1, Pp 992-1001 (2017)
While progress has been made in treating cancer, cytotoxic chemotherapeutic agents are still the most widely used drugs and are associated with severe side-effects. Drugs that target unique molecular signalling pathways are needed for treating cancer
Externí odkaz:
https://doaj.org/article/5b1f57a865f84b7198b25962377a1156
Autor:
Dominik Bakalarz, Edyta Korbut, Zhengnan Yuan, Bingchen Yu, Dagmara Wójcik, Aleksandra Danielak, Katarzyna Magierowska, Slawomir Kwiecień, Tomasz Brzozowski, Monika Marcinkowska, Binghe Wang, Marcin Magierowski
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 10, p 5211 (2021)
Hydrogen sulfide (H2S) is an endogenously produced molecule with anti-inflammatory and cytoprotective properties. We aimed to investigate for the first time if a novel, esterase-sensitive H2S-prodrug, BW-HS-101 with the ability to release H2S in a co
Externí odkaz:
https://doaj.org/article/fbf8a360c4344b97a8737aa0417f0131
Autor:
Wenyi Wang, Binghe Wang
Publikováno v:
Frontiers in Chemistry, Vol 6 (2018)
SO2 is widely recognized as an air pollutant and is a known cause of acid rain. At a sufficiently high level, it also causes respiratory diseases. A much lesser known side of SO2 is its endogenous nature and possible physiological roles. There is mou
Externí odkaz:
https://doaj.org/article/6274829a4c804482804b00a608e6436d
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 5, Iss 5, Pp 367-377 (2015)
Hydrogen sulfide (H2S) is recognized as one of three gasotransmitters together with nitric oxide (NO) and carbon monoxide (CO). As a signaling molecule, H2S plays an important role in physiology and shows great potential in pharmaceutical application
Externí odkaz:
https://doaj.org/article/20da590b237149869cc890b7ebf0b365