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pro vyhledávání: '"Binggang, Sun"'
Publikováno v:
Methods in enzymology. 629
Over the past two decades there have been tremendous advances in our understanding of tumor immunology, which have in turn led to new and exciting immunology-based therapeutics. However, further research is needed into the dynamics and regulation of
Over the past two decades there have been tremendous advances in our understanding of tumor immunology, which have in turn led to new and exciting immunology-based therapeutics. However, further research is needed into the dynamics and regulation of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ab54124885a7131b868f3a02bd73eff0
https://doi.org/10.1016/bs.mie.2019.06.001
https://doi.org/10.1016/bs.mie.2019.06.001
Publikováno v:
Cancer Research. 79:4117-4117
Immune checkpoint molecules are important regulators of immune activation. This regulation is critical to maintaining immune homeostasis, and is driven by a complex interplay of both co-stimulatory and inhibitory signals. These checkpoints are key to
Publikováno v:
The Journal of Immunology. 202:194.40-194.40
Metastasis to distant organs is responsible for ~90% of cancer-related deaths. Adhesion molecules are cell surface proteins that mediate the interactions between disseminated tumor cells and the endothelium of blood vessels present in the tumor micro
Publikováno v:
The Journal of Immunology. 202:130.25-130.25
The inflammation of neuronal tissues is triggered by various stimuli such as traumatic brain injury, stroke, protein aggregation and pathogens. Neuroinflammation cues such as brain injury lead to protein release and microglia activation, which in tur
Autor:
Binggang Sun, Priyanka Rughwani, Kay Chow, Amy Zhao, Jason Lehmann, Weiping Jiang, Shaoquan Ji
Publikováno v:
The Journal of Immunology. 202:130.24-130.24
Exposure to foreign material triggers host immune responses, which are primarily mediated by leukocytes including macrophages, neutrophils, dendritic cells, NK cells, T cells and B cells. These cells produce an array of soluble factors which coordina
Publikováno v:
The Journal of Immunology. 200:174.30-174.30
Immune responses are mediated by innate immune cells (e.g., macrophages) and subsequently, adaptive immune cells (e.g., T and B cells). Macrophages secrete an array of inflammatory mediators to affect their host defense, tissue repair, and immunoregu
Publikováno v:
The Journal of Immunology. 200:164.14-164.14
In response to pathogens, especially viruses, cells release interferons and other cytokines to combat infection. Interferons are typically divided into three types: 1 (e.g., IFN-α, IFN-β), 2 (e.g., IFN-γ), and 3 (e.g., IFN-λ1, IFN-λ2). All inter
Publikováno v:
The Journal of Immunology. 177:3439-3447
Leukotriene B4 (LTB4) is a potent activator and chemoattractant for leukocytes and is implicated in several inflammatory diseases. The actions of LTB4 are mediated by two cell surface receptors, BLT1, which is predominantly expressed in peripheral bl
Publikováno v:
Molecular Biology of the Cell. 14:4526-4540
Mitogen-activated protein kinase cascades regulate various cellular functions, including growth, cell differentiation, development, and stress responses. We have identified a new Dictyostelium kinase (stress-activated protein kinase [SAPK]alpha), whi