Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Bingchuan Zhao"'
Publikováno v:
Organic & Biomolecular Chemistry. 16:5764-5770
Antimicrobial peptides (AMPs) are short cationic peptides with a high affinity for membranes and emerged as a promising therapeutic approach with potential for treating infectious diseases. Chemical stabilization of short peptides proved to be a succ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5a4f5e7c075b0630303a1b1b9574f1a
https://doi.org/10.1039/c8ob00483h
https://doi.org/10.1039/c8ob00483h
Publikováno v:
Journal of Peptide Science. 22:540-544
Thiol–ene reactions have been used in a variety of applications that mostly involve an inter-molecular pathway. Herein, we report a facile method to construct thioether-tethered cyclic peptides via an intra-molecular thiol–ene reaction. This reac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::20b664220f1aa98c38ebabffe7124f15
https://doi.org/10.1002/psc.2902
https://doi.org/10.1002/psc.2902
Autor:
Tzi Bun Ng, Jianpeng Wang, Jiang Xia, Shangrong Fan, Yuxia Zhu, Zigang Li, Dan Yang, Bingchuan Zhao, John Wong, Cuiming Yin
Publikováno v:
ChemBioChem. 17:1416-1420
We report a β-hairpin dual stabilizing strategy: a d-proline-l-proline (d-Pro-l-Pro) dipeptide as the nucleating turn, and a thioether tether as a side-chain linkage at a precisely designed position to stabilize the β-hairpin. This method was used
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09c50f2049cc9329ecfb45a3c09fdf66
https://doi.org/10.1002/cbic.201600179
https://doi.org/10.1002/cbic.201600179
Autor:
Yun-Dong Wu, Spiros Liras, Kun Song, Mark Edward Flanagan, David Price, Tao Wang, Guoyun Bai, Fan Jiang, Zigang Li, Bingchuan Zhao, Huacan Lin, Yujie Wu, Meihua Tu, Mingsheng Xie, Adam M. Gilbert, Gilles H. Goetz, Alan A. Mathiowetz, Yuan Tian, Qingzhou Zhang
Publikováno v:
Scientific Reports
Inducing α-helicity through side-chain cross-linking is a strategy that has been pursued to improve peptide conformational rigidity and bio-availability. Here we describe the preparation of small peptides tethered to chiral sulfoxide-containing macr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa486ad9fcf1e0e9fd8b0863497d3043
http://europepmc.org/articles/PMC5146914
http://europepmc.org/articles/PMC5146914
Publikováno v:
Journal of peptide science : an official publication of the European Peptide Society. 22(8)
Thiol-ene reactions have been used in a variety of applications that mostly involve an inter-molecular pathway. Herein, we report a facile method to construct thioether-tethered cyclic peptides via an intra-molecular thiol-ene reaction. This reaction
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f6f01698f0ab55e1bfcf9f3bb91493fc
https://pubmed.ncbi.nlm.nih.gov/27378284
https://pubmed.ncbi.nlm.nih.gov/27378284
Publikováno v:
Current topics in medicinal chemistry. 16(2)
Defensins are small cationic cysteine rich peptides, which usually contain 18-45 amino acids and possess amphiphilic properties. The term "defensin" was coined as the sequences of rabbit and human leukin/phagocytin molecules were first reported in 19
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::174c148dff08863e7ef51c710b65e28e
https://pubmed.ncbi.nlm.nih.gov/26126908
https://pubmed.ncbi.nlm.nih.gov/26126908
Publikováno v:
RSC Advances. 3:13106
Herein we report the first silver catalyzed fluorinated quinoline synthesis via a cascade alkyne–ketone–amino coupling/addition/condensation process in water.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f8c6ce04007015fa562a65d8c55528f4
https://doi.org/10.1039/c3ra41991f
https://doi.org/10.1039/c3ra41991f