Zobrazeno 1 - 10
of 132
pro vyhledávání: '"Bingbing Dai"'
Autor:
Maria Gagliardi, Rhonda Kean, Bingbing Dai, Jithesh Jose Augustine, Michael Roberts, Jason Fleming, D. Craig Hooper, Ana Tari Ashizawa
Publikováno v:
Biomedicines, Vol 12, Iss 8, p 1901 (2024)
Overexpression and aberrant activation of signal transducer and activator of transcription 3 (STAT3) contribute to tumorigenesis, drug resistance, and tumor-immune evasion, making it a potential cancer therapeutic target. BP1003 is a neutral liposome
Externí odkaz:
https://doaj.org/article/f2009c519c1e47bbb1d16259b222484d
Autor:
Yulan Chen, Qiao Wang, Haina Liu, Lei Jin, Xin Feng, Bingbing Dai, Meng Chen, Fangran Xin, Tingting Wei, Bingqing Bai, Zhijun Fan, Jiahui Li, Yuxin Yao, Ruobing Liao, Jintao Zhang, Xiangnan Jin, Lingyu Fu
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
ObjectiveAlthough Leflunomide (LEF) is effective in treating rheumatoid arthritis (RA), there are still a considerable number of patients who respond poorly to LEF treatment. Till date, few LEF efficacy-predicting biomarkers have been identified. Her
Externí odkaz:
https://doaj.org/article/12a2721273bd4b358d226280cf6da028
Autor:
Juan Yang, Qiaohong Liao, Kaiwei Luo, Fengfeng Liu, Yonghong Zhou, Gang Zou, Wei Huang, Shuanbao Yu, Xianglin Wei, Jiaxin Zhou, Bingbing Dai, Qi Qiu, Ralf Altmeyer, Hongan Hu, Juliette Paireau, Li Luo, Lidong Gao, Birgit Nikolay, Shixiong Hu, Weijia Xing, Peng Wu, H. Rogier van Doorn, Peter W. Horby, Peter Simmonds, Gabriel M. Leung, Benjamin J. Cowling, Simon Cauchemez, Hongjie Yu
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-10 (2022)
Hand, foot and mouth disease, caused by enterovirus A71 (EV-A71) infection, is common in children in China. Here, the authors estimate EV-A71 incidence and seroprevalence using data from two longitudinal cohorts and find that, despite high infection
Externí odkaz:
https://doaj.org/article/13d825dff5bb4fdc98370d3db1ad55c8
Autor:
Jiaxin Zhou, Yonghong Zhou, Kaiwei Luo, Qiaohong Liao, Wen Zheng, Hui Gong, Huilin Shi, Shanlu Zhao, Kai Wang, Qi Qiu, Bingbing Dai, Lingshuang Ren, Lili Wang, Lidong Gao, Meng Xu, Nuolan Liu, Wanying Lu, Nan Zheng, Xinhua Chen, Zhiyuan Chen, Juan Yang, Simon Cauchemez, Hongjie Yu
Publikováno v:
BMC Medicine, Vol 20, Iss 1, Pp 1-11 (2022)
Abstract Background A major hand-foot-and-mouth disease (HFMD) pathogen, coxsackievirus A16 (CVA16), has predominated in several of the last 10 years and caused the largest number of HFMD outbreaks between 2011 and 2018 in China. We evaluated the eff
Externí odkaz:
https://doaj.org/article/2eeb4827b00a445d827414f860c5f711
Autor:
Bingbing Dai, Jithesh J. Augustine, Ya’an Kang, David Roife, Xinqun Li, Jenying Deng, Lin Tan, Leona A. Rusling, John N. Weinstein, Philip L. Lorenzi, Michael P. Kim, Jason B. Fleming
Publikováno v:
Cell Death and Disease, Vol 12, Iss 7, Pp 1-11 (2021)
Abstract Nuclear factor erythroid 2-related factor 2 (NRF2) is aberrantly activated in about 93% of pancreatic cancers. Activated NRF2 regulates multiple downstream molecules involved in cancer cell metabolic reprogramming, translational control, and
Externí odkaz:
https://doaj.org/article/16cff39c74954feaa55f9afe71d7a3b7
Publikováno v:
Human Vaccines & Immunotherapeutics, Vol 17, Iss 2, Pp 592-600 (2021)
China has achieved high vaccination coverage under the Expanded Program on Immunization (EPI) in children 1–2 years of age. However, a knowledge gap exists regarding vaccination coverage and timeliness for children >2 years of age. As such, this st
Externí odkaz:
https://doaj.org/article/436fe14ae9914f4c909a406af7e99786
Autor:
Fahmi Mesmar, Bingbing Dai, Ahmed Ibrahim, Linnea Hases, Mohammed Hakim Jafferali, Jithesh Jose Augustine, Sebastian DiLorenzo, Ya'an Kang, Yang Zhao, Jing Wang, Michael Kim, Chin‐Yo Lin, Anders Berkenstam, Jason Fleming, Cecilia Williams
Publikováno v:
Cancer Medicine, Vol 8, Iss 18, Pp 7705-7719 (2019)
Abstract Despite advances in cancer therapeutics, pancreatic cancer remains difficult to treat and often develops resistance to chemotherapies. We have evaluated a bioavailable genistein analogue, AXP107‐11 which has completed phase Ib clinical tri
Externí odkaz:
https://doaj.org/article/900afa4941d14028b0d39be55bc5e75d
Autor:
Jenying Deng, Yaan Kang, Chien-Chia Cheng, Xinqun Li, Bingbing Dai, Matthew H. Katz, Taoyan Men, Michael P. Kim, Eugene A. Koay, Huocong Huang, Rolf A. Brekken, Jason B. Fleming
Publikováno v:
JCI Insight, Vol 6, Iss 17 (2021)
Pancreatic ductal adenocarcinoma (PDAC) tumors are characterized by a desmoplastic reaction resulting in dense deposition of collagen that is known to promote cancer progression. A central mediator of protumorigenic collagen signaling is the receptor
Externí odkaz:
https://doaj.org/article/6534f5a2324842ac8f6e0b149ce8159e
Autor:
Mayrim V. Rios Perez, David Roife, Bingbing Dai, Michael Pratt, Ryszard Dobrowolski, Ya'an Kang, Xinqun Li, Jithesh J. Augustine, Rafal Zielinski, Waldemar Priebe, Jason B. Fleming
Publikováno v:
Surgery Open Science, Vol 1, Iss 2, Pp 56-63 (2019)
Background: Auranofin, a Food and Drug Administration–approved anti-rheumatic agent with anticancer properties for lung and ovarian cancer, has never been studied for pancreatic cancer. We hypothesize that auranofin may prevent pancreatic ductal ad
Externí odkaz:
https://doaj.org/article/8c733fed64cf494fa7abb5b45dd29bc7
Autor:
Ming Li, Bingbing Dai, Yawei Tang, Lei Lei, Ningning Li, Chang Liu, Teng Ge, Lilong Zhang, Yao Xu, Yuqi Hu, Pengfei Li, Yan Zhang, Jieli Yuan, Xia Li
Publikováno v:
mSystems, Vol 4, Iss 2 (2019)
ABSTRACT Intestinal bacterial dysbiosis has been increasingly linked to ankylosing spondylitis (AS), which is a prototypic and best studied subtype of spondyloarthritis (SpA). Fungi and bacteria coexist in the human gut and interact with each other.
Externí odkaz:
https://doaj.org/article/213c8774aba3419eab80294496659b8c