Zobrazeno 1 - 10
of 71
pro vyhledávání: '"Bing-rui Zhou"'
Autor:
Dustin C. Becht, Brianna J. Klein, Akinori Kanai, Suk Min Jang, Khan L. Cox, Bing-Rui Zhou, Sabrina K. Phanor, Yi Zhang, Ruo-Wen Chen, Christopher C. Ebmeier, Catherine Lachance, Maxime Galloy, Amelie Fradet-Turcotte, Martha L. Bulyk, Yawen Bai, Michael G. Poirier, Jacques Côté, Akihiko Yokoyama, Tatiana G. Kutateladze
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-20 (2023)
Human acetyltransferases MOZ and MORF mediate development programs and are dysregulated in diseases. Here the authors identified two winged helix (WH) domains in MORF/MOZ and characterized their DNA binding functions, including targeting of CpG by WH
Externí odkaz:
https://doaj.org/article/a2ad2ef5ddc546e58f71dca700b8f668
Autor:
Ping Dong, Qiong Xu, Ying Zhang, Dong-yun Li, Bing-rui Zhou, Chun-chun Hu, Chun-xue Liu, Xin-rui Tang, Shi-yun Fu, Lan Zhang, Hai-feng Li, Fei-yong Jia, Xiu-bin Tong, Jie Wang, Hui-ping Li, Xiu Xu
Publikováno v:
Frontiers in Pediatrics, Vol 11 (2023)
ObjectiveEarly identification and intervention for children with global developmental delay (GDD) can significantly improve their prognosis and reduce the possibility of developing intellectual disability in the future. This study aimed to explore th
Externí odkaz:
https://doaj.org/article/f5a9c45acb0f4aff81cabbf8e2b0d3da
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
Chromosome segregation requires the association of the kinetochore protein complex with a specialized nucleosome at the centromere. Here, the authors present cryo-EM and mutational studies that provide insights into the structure of the budding yeast
Externí odkaz:
https://doaj.org/article/763685637eb344f2b203a00440b62909
Autor:
Bing-Rui Zhou, Yawen Bai
Publikováno v:
STAR Protocols, Vol 2, Iss 2, Pp 100396- (2021)
Summary: The chromatosome, a nucleosome bound to a histone H1, is the structural unit of metazoan chromatin. Determination of the high-resolution structure of the chromatosome is challenging due to the dynamic nature of H1 binding. Here, we present a
Externí odkaz:
https://doaj.org/article/25af1b6dd16942878f327689e78497b6
Atomic resolution cryo-EM structure of a native-like CENP-A nucleosome aided by an antibody fragment
Autor:
Bing-Rui Zhou, K. N. Sathish Yadav, Mario Borgnia, Jingjun Hong, Baohua Cao, Ada L. Olins, Donald E. Olins, Yawen Bai, Ping Zhang
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-7 (2019)
CENP-A histone variants replace histones H3 at centromeres. Here the authors use a single-chain antibody fragment (scFv) to stabilize human CENP-A nucleosome containing a native α-satellite DNA and solved its structure by cryo-EM to 2.6 Å resolutio
Externí odkaz:
https://doaj.org/article/510fb8f60bd045f78e1fc1422101e0d3
Publikováno v:
BMC Medical Genetics, Vol 19, Iss 1, Pp 1-6 (2018)
Abstract Background Autism spectrum disorder (ASD) is a neurodevelopmental disorder in which genetics plays a key aetiological role. The gene encoding NAD(P)H steroid dehydrogenase-like protein (NSDHL) is expressed in developing cortical neurons and
Externí odkaz:
https://doaj.org/article/1d02212c3d5f4786873991b99d24bbae
Autor:
Qian Ma, Jun-Bao Fan, Zheng Zhou, Bing-Rui Zhou, Sheng-Rong Meng, Ji-Ying Hu, Jie Chen, Yi Liang
Publikováno v:
PLoS ONE, Vol 7, Iss 4, p e36288 (2012)
Amyloid fibrils associated with neurodegenerative diseases can be considered biologically relevant failures of cellular quality control mechanisms. It is known that in vivo human Tau protein, human prion protein, and human copper, zinc superoxide dis
Externí odkaz:
https://doaj.org/article/062aac2a4a2c45cabe4f03624f429a83
Autor:
Martin R. Singleton, Emily M. He, Tengfei Lian, Bing-Rui Zhou, Carl Wu, Yawen Bai, Ruifang Guan
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
Nature Communications
Nature Communications
Accurate chromosome segregation relies on the specific centromeric nucleosome–kinetochore interface. In budding yeast, the centromere CBF3 complex guides the deposition of CENP-A, an H3 variant, to form the centromeric nucleosome in a DNA sequence-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1da1c0c12d9c802c64449e6c429c4749
https://doaj.org/article/763685637eb344f2b203a00440b62909
https://doaj.org/article/763685637eb344f2b203a00440b62909
Publikováno v:
Journal of molecular biology. 434(19)
Linker histone H1, facilitated by its chaperones, plays an essential role in regulating gene expression by maintaining chromatin's higher-order structure and epigenetic state. However, we know little about the structural mechanism of how the chaperon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c8ce405a018f05ea9b0cfb5019b04c4
https://pubmed.ncbi.nlm.nih.gov/35870650
https://pubmed.ncbi.nlm.nih.gov/35870650
Publikováno v:
SSRN Electronic Journal.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9395162f65b3648898e7edc025e58a7f
https://doi.org/10.2139/ssrn.4106200
https://doi.org/10.2139/ssrn.4106200