Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Bing-Yu Luh"'
Autor:
Joanne J. Bronson, Stella Huang, Dane M. Springer, Qi Gao, Goodrich Jason, Kenneth DenBleyker, Thomas J. Dougherty, Bing-Yu Luh, Joan Fung-Tomc
Publikováno v:
Letters in Drug Design & Discovery. 5:327-331
Publikováno v:
Bioorganic & Medicinal Chemistry. 11:281-291
Twenty-seven novel cephalosporin derivatives with activity against methicillin-resistant Staphylococcus aureus (MRSA) are described. The compounds contain novel acid moieties at C-7 that were synthesized using nucleophilic aromatic substitution react
Publikováno v:
Bioorganic & Medicinal Chemistry. 11:265-279
Forty-five novel cephalosporin derivatives with activity against methicillin-resistant Staphylococcus aureus (MRSA) are described. The compounds contain novel cinnamic acid moieties at C-7 that were synthesized using a key Heck reaction followed by n
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 11:797-801
Sixteen novel cephalosporin derivatives with activity against methicillin-resistant Staphylococcus aureus (MRSA) are described. The compounds were synthesized using substituted thiopyridones, generated either by cyclization of functionalized precurso
Autor:
John D. Dimarco, Shankar Swaminathan, Brian Burke, Thomas P. Kissick, Oak K. Kim, Bin Zheng, Janak Singh, Kenneth J. Natalie, Goodrich Jason, Juliya Livshits, Matthew A. Brown, John A. Grosso, Zhinong Gao, Michael J. Humora, Anthony P. Dutka, Peter Hans Ermann, David R. Kronenthal, Gerard A. Crispino, Richard H. Mueller, John A. Wichtowski, Jeffrey T. North, Joanne J. Bronson, Jack Z. Gougoutas, Yasutsugu Ueda, Dane M. Springer, Peter Schierling, Bing Yu Luh, James E. Heikes, Dau-Ming Hsieh, Anne J. Pullockaran, Bo Zhang, Robert K. Perrone, Mei C. Lai, and Theodor W. Denzel, Yunhui Zhang
Publikováno v:
Organic Process Research & Development. 4:488-497
A practical synthesis of the anti-methicillin resistant Staphylococcus aureus cephem (6R-trans)-E-7-[[[[2,5-dichloro-4-[3-[(carboxymethyl)amino]-3-oxo-1-propenyl]phenyl]-thio]-acetyl]amino]-4-[[(2-carboxy-8-oxo-5-thia-1-azabicyclo-[4.2.0]oct-2-en-3-y
Publikováno v:
Tetrahedron Letters. 35:3017-3020
Regiospecific synthesis of alkylated A ring of arotinoids has been achieved by using Me3Al-TMSOSO2CF3 as a key reagent for conversion of carbonyl to a geminal dimethyl functionality.
Autor:
Muzammil M. Mansuri, Peter F. Misco, Gregory S. Bisacchi, Bing Yu Luh, Brian Terry, Choung U. Kim
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 3:1571-1576
A series of thymidine analogues substituted with alkoxy groups of the C-4 position of the furan ring were synthesized. Among these compounds, the methoxy analogue 9 was the most potent inhibitor of herpes simplex virus type 1 thymidine kinase.
Publikováno v:
ChemInform. 22
A novel synthetic methodology for the hydroxymethyl substituted acyclic acetal functionality was developed, The rationally designed phosphonate analogue 3 of ganciclovir monophosphate was highly active against human cytomegalovirus.
Publikováno v:
ChemInform. 22
Autor:
Choung U. Kim, John C. Martin, M. J. M. Hitchcook, Peter F. Misco, Ismail Ghazzouli, Bing-Yu Luh
Publikováno v:
ChemInform. 23