Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Bing-Shao Chia"'
Autor:
Bing-Shao Chia, Fedora Lanzas, Dalin Rifat, Aubrey Herrera, Elizabeth Y Kim, Christine Sailer, Edith Torres-Chavolla, Purvaja Narayanaswamy, Viktor Einarsson, Jaime Bravo, Juan M Pascale, Thomas R Ioerger, James C Sacchettini, Petros C Karakousis
Publikováno v:
PLoS ONE, Vol 7, Iss 7, p e40456 (2012)
The frequency of individual genetic mutations conferring drug resistance (DR) to Mycobacterium tuberculosis has not been studied previously in Central America, the place of origin of many immigrants to the United States. The current gold standard for
Externí odkaz:
https://doaj.org/article/66164b15925a4c009ca55f00ee068d78
AAV-CRISPR-Cas13 eliminates human enterovirus and prevents death of infected miceResearch in context
Autor:
Choong Tat Keng, Thinesshwary Yogarajah, Regina Ching Hua Lee, Irfan Bin Hajis Muhammad, Bing Shao Chia, Suraj Rajan Vasandani, Daryl Shern Lim, Ke Guo, Yi Hao Wong, Chee Keng Mok, Justin Jang Hann Chu, Wei Leong Chew
Publikováno v:
EBioMedicine, Vol 93, Iss , Pp 104682- (2023)
Summary: Background: RNA viruses account for many human diseases and pandemic events but are often not targetable by traditional therapeutics modalities. Here, we demonstrate that adeno-associated virus (AAV) -delivered CRISPR-Cas13 directly targets
Externí odkaz:
https://doaj.org/article/d913a4522d6244fb8aee77bc8780cbd7
Autor:
Bo Li, Sara M. Clohisey, Bing Shao Chia, Bo Wang, Ang Cui, Thomas Eisenhaure, Lawrence D. Schweitzer, Paul Hoover, Nicholas J. Parkinson, Aharon Nachshon, Nikki Smith, Tim Regan, David Farr, Michael U. Gutmann, Syed Irfan Bukhari, Andrew Law, Maya Sangesland, Irit Gat-Viks, Paul Digard, Shobha Vasudevan, Daniel Lingwood, David H. Dockrell, John G. Doench, J. Kenneth Baillie, Nir Hacohen
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-18 (2020)
Here, Li et al. perform a genome-wide CRISPR screen to identify host dependency factors for influenza A virus infection and show that the host mRNA cap methyltransferase CMTR1 is important for viral cap snatching and that it affects expression of ant
Externí odkaz:
https://doaj.org/article/c1f734a4d6574c6d950eb373c2f18352
Autor:
Dhiraj Acharya, Rebecca Reis, Meta Volcic, GuanQun Liu, May K. Wang, Bing Shao Chia, Rayhane Nchioua, Rüdiger Groß, Jan Münch, Frank Kirchhoff, Konstantin M.J. Sparrer, Michaela U. Gack
Publikováno v:
Cell. 185(19)
The current dogma of RNA-mediated innate immunity is that sensing of immunostimulatory RNA ligands is sufficient for the activation of intracellular sensors and induction of interferon (IFN) responses. Here, we report that actin cytoskeleton disturba
Autor:
Nir Hacohen, Ang Cui, Raktima Raychowdhury, David J. Lieb, Bo Li, Bing Shao Chia, Thomas Eisenhaure
Publikováno v:
Journal of Virology
Viral infection triggers the secretion of type I interferons, which in turn induce the expression of hundreds of antiviral genes. However, the roles of these induced genes in controlling viral infections remain largely unknown, limiting our ability t
Autor:
Syed I. A. Bukhari, Sara Clohisey, John G. Doench, Paul Hoover, Paul Digard, Nicholas J. Parkinson, Daniel Lingwood, Maya Sangesland, Bo Wang, Tim Regan, Thomas Eisenhaure, Nir Hacohen, Irit Gat-Viks, Shobha Vasudevan, Bo Li, Nikki Smith, Lawrence D. Schweitzer, David H. Dockrell, David Farr, Bing Shao Chia, Michael U. Gutmann, Andy Law, Ang Cui, J Kenneth Baillie, Aharon Nachshon
Publikováno v:
Nature Communications
Nature Communications, Vol 11, Iss 1, Pp 1-18 (2020)
Li, B, Clohisey, S M, Chia, B S, Wang, B, Cui, A, Eisenhaure, T, Schweitzer, L D, Hoover, P, Parkinson, N J, Nachshon, A, Smith, N, Regan, T, Farr, D, Gutmann, M U, Bukhari, S I, Law, A, Sangesland, M, Gat-viks, I, Digard, P, Vasudevan, S, Lingwood, D, Dockrell, D H, Doench, J G, Baillie, J K & Hacohen, N 2020, ' Genome-wide CRISPR screen identifies host dependency factors for influenza A virus infection ', Nature Communications, vol. 11, no. 1, 164 . https://doi.org/10.1038/s41467-019-13965-x
Nature Communications, Vol 11, Iss 1, Pp 1-18 (2020)
Li, B, Clohisey, S M, Chia, B S, Wang, B, Cui, A, Eisenhaure, T, Schweitzer, L D, Hoover, P, Parkinson, N J, Nachshon, A, Smith, N, Regan, T, Farr, D, Gutmann, M U, Bukhari, S I, Law, A, Sangesland, M, Gat-viks, I, Digard, P, Vasudevan, S, Lingwood, D, Dockrell, D H, Doench, J G, Baillie, J K & Hacohen, N 2020, ' Genome-wide CRISPR screen identifies host dependency factors for influenza A virus infection ', Nature Communications, vol. 11, no. 1, 164 . https://doi.org/10.1038/s41467-019-13965-x
Host dependency factors that are required for influenza A virus infection may serve as therapeutic targets as the virus is less likely to bypass them under drug-mediated selection pressure. Previous attempts to identify host factors have produced lar
Autor:
Yee Sin Leo, Marc Lecuit, Thérèse Couderc, Angela Chow, Zhisheng Her, Yiu-Wing Kam, Bing Shao Chia, Ruo-Yan Ong, Fok-Moon Lum, Laurent Rénia, Lisa F. P. Ng
Publikováno v:
Scientific Reports
Scientific Reports, Nature Publishing Group, 2018, 8 (1), pp.1860. ⟨10.1038/s41598-018-20305-4⟩
Scientific Reports, 2018, 8 (1), pp.1860. ⟨10.1038/s41598-018-20305-4⟩
Scientific Reports, Vol 8, Iss 1, Pp 1-14 (2018)
Scientific Reports, Nature Publishing Group, 2018, 8 (1), pp.1860. ⟨10.1038/s41598-018-20305-4⟩
Scientific Reports, 2018, 8 (1), pp.1860. ⟨10.1038/s41598-018-20305-4⟩
Scientific Reports, Vol 8, Iss 1, Pp 1-14 (2018)
The arthropod-transmitted chikungunya virus (CHIKV) causes a flu-like disease that is characterized by incapacitating arthralgia. The re-emergence of CHIKV and the continual risk of new epidemics have reignited research in CHIKV pathogenesis. Virus-s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1af94af298b853bb75332bfd48784e07
https://hal-pasteur.archives-ouvertes.fr/pasteur-02185035
https://hal-pasteur.archives-ouvertes.fr/pasteur-02185035
Autor:
Bing Shao Chia1,2, Bo Li1,2, Ang Cui2, Eisenhaure, Thomas2, Raychowdhury, Raktima2, Lieb, David2, Hacohen, Nir1,2,3 nhacohen@mgh.harvard.edu
Publikováno v:
Journal of Virology. Nov2020, Vol. 94 Issue 22, p1-18. 18p.
Autor:
Elizabeth Kim, Bing Shao Chia, James C. Sacchettini, Juan Miguel Pascale, Viktor Einarsson, Dalin Rifat, Edith Torres-Chavolla, Thomas R. Ioerger, Purvaja Narayanaswamy, Petros C. Karakousis, Jaime Cervera Bravo, Fedora Lanzas, Christine Sailer, Aubrey V. Herrera
Publikováno v:
PLoS ONE, Vol 7, Iss 7, p e40456 (2012)
PLoS ONE
PLoS ONE
The frequency of individual genetic mutations conferring drug resistance (DR) to Mycobacterium tuberculosis has not been studied previously in Central America, the place of origin of many immigrants to the United States. The current gold standard for
Publikováno v:
PLoS Currents
Seroprevalence of antibodies against influenza viruses from 1000 people between the ages of 0 to 90 years of age (100 samples for each decade of life) in the Pittsburgh, PA, USA was measured. One year removed from the outbreak of novel H1N1 influenza