Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Bing Yu Zou"'
Autor:
Gregory M. LaMonte, Frances Rocamora, Danushka S. Marapana, Nina F. Gnädig, Sabine Ottilie, Madeline R. Luth, Tilla S. Worgall, Gregory M. Goldgof, Roxanne Mohunlal, T. R. Santha Kumar, Jennifer K. Thompson, Edgar Vigil, Jennifer Yang, Dylan Hutson, Trevor Johnson, Jianbo Huang, Roy M. Williams, Bing Yu Zou, Andrea L. Cheung, Prianka Kumar, Timothy J. Egan, Marcus C. S. Lee, Dionicio Siegel, Alan F. Cowman, David A. Fidock, Elizabeth A. Winzeler
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Imidazolopiperazines (IZPs) are a class of compounds under clinical development for malaria, but their mechanism of action is unclear. Here, the authors show that IZPs inhibit the parasite’s secretory pathway, affecting protein trafficking and expo
Externí odkaz:
https://doaj.org/article/30325ebc8f1440eb95a7ef787cbdca69
Autor:
Gregory M. LaMonte, Pamela Orjuela-Sanchez, Jaeson Calla, Lawrence T. Wang, Shangzhong Li, Justine Swann, Annie N. Cowell, Bing Yu Zou, Alyaa M. Abdel-Haleem Mohamed, Zaira Hellen Villa Galarce, Marta Moreno, Carlos Tong Rios, Joseph M. Vinetz, Nathan Lewis, Elizabeth A. Winzeler
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
Host-parasite interactions during the exoerythrocytic stage of Plasmodium infection remains poorly understood. Using dual RNA-Seq, the authors show that human mucosal immunity protein mucin-13 is upregulated during Plasmodium hepatic-stage infection
Externí odkaz:
https://doaj.org/article/4951c6ea139b4323a6d31d29038c5820
Autor:
Jaeson Calla, Nimisha Mittal, Greg LaMonte, Benjamin Liffner, Karla P. Godinez-Macias, Krypton Carolino, Gregory T. Walker, Bing Yu Zou, Emma Paytas, Layné Guerra, Carlos Tong-Rios, Brice Campo, Joseph M. Vinetz, Dionicia Gamboa, Manuela Raffatellu, Sabrina Absalon, Elizabeth A. Winzeler
Changes in host cell morphology and transcription after apicomplexan parasite infection have long been noted, but there have been few studies of the functional consequences of host cell remodeling. Here we show, using time-dependent immunofluorescenc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::146eb450ddcd2b932db11551ebb083c6
https://doi.org/10.1101/2022.11.22.517223
https://doi.org/10.1101/2022.11.22.517223
Autor:
Jennifer A. Yang, Bing Yu Zou, Frances Rocamora, Edgar Vigil, Prianka Kumar, Nina F. Gnädig, Alan F. Cowman, David A. Fidock, Roy Williams, Trevor Johnson, Madeline R. Luth, Danushka S. Marapana, Dylan Hutson, Marcus C. S. Lee, Tilla S. Worgall, Jianbo Huang, Gregory M. Goldgof, Gregory LaMonte, T. R. Santha Kumar, Jennifer K. Thompson, Timothy J. Egan, Roxanne Mohunlal, Sabine Ottilie, Dionicio Siegel, Elizabeth A. Winzeler, Andrea L. Cheung
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Nature Communications
Nature communications, vol 11, iss 1
Nature Communications
Nature communications, vol 11, iss 1
A promising new compound class for treating human malaria is the imidazolopiperazines (IZP) class. IZP compounds KAF156 (Ganaplacide) and GNF179 are effective against Plasmodium symptomatic asexual blood-stage infections, and are able to prevent tran
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b18290350407667761814a3f37b90a3
https://doaj.org/article/30325ebc8f1440eb95a7ef787cbdca69
https://doaj.org/article/30325ebc8f1440eb95a7ef787cbdca69
Autor:
Jaeson Calla, Elizabeth A. Winzeler, Alyaa Mohamed, Zaira Hellen Villa Galarce, Gregory LaMonte, Annie N. Cowell, Bing Yu Zou, Lawrence T. Wang, Joseph M. Vinetz, Justine Swann, Carlos Tong Rios, Pamela Orjuela-Sánchez, Shangzhong Li, Marta Moreno, Nathan E. Lewis
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
Nature Communications
Nature communications, vol 10, iss 1
Nature Communications
Nature communications, vol 10, iss 1
The exoerythrocytic stage of Plasmodium infection is a critical window for prophylactic intervention. Using genome-wide dual RNA sequencing of flow-sorted infected and uninfected hepatoma cells we show that the human mucosal immunity gene, mucin-13 (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17ed722df4d47d8dd42a25588671ea21
http://link.springer.com/article/10.1038/s41467-019-08349-0
http://link.springer.com/article/10.1038/s41467-019-08349-0
Autor:
LaMonte, Gregory M., Almaliti, Jehad, Bibo-Verdugo, Betsaida, Keller, Lena, Bing Yu Zou, Yang, Jennifer, Antonova-Koch, Yevgeniya, Orjuela-Sanchez, Pamela, Boyle, Colleen A., Vigil, Edgar, Wang, Lawrence, Goldgof, Gregory M., Gerwick, Lena, O'Donoghue, Anthony J., Winzeler, Elizabeth A., Gerwick, William H., Ottilie, Sabine
Publikováno v:
Journal of Medicinal Chemistry; 8/10/2017, Vol. 60 Issue 15, p6721-6732, 12p