Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Bing‐Qiu Li"'
Publikováno v:
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 16, Iss 2, Pp n/a-n/a (2024)
Abstract INTRODUCTION Vascular pathology is known to contribute to dementia and vascular endothelial growth factor (VEGF) is a well‐established biomarker associated with vascular alterations. Nonetheless, research findings on VEGF in Alzheimer's di
Externí odkaz:
https://doaj.org/article/2464fb5a567f4b809ef25ea7af5cd6e8
Publikováno v:
Journal of Alzheimer's Disease. 91:877-893
Background: Alzheimer’s disease (AD) is the most common form of neurodegenerative dementia among the elderly. Excitotoxicity has been implicated as playing a dominant role in AD, especially related to the hyperactivation of excitatory neurons. Deat
Autor:
Bing-qiu Li, Ling-zhi Xu, Fang-yu Li, Ying Li, Yu Zhao, Heng Zhang, Mei-na Quan, Jian-ping Jia
Publikováno v:
Molecular Neurobiology. 59:3370-3381
Alzheimer's disease (AD) is the most common form of neurodegenerative disease and most anti-AD drugs have failed in clinical trials; hence, it is urgent to find potentially effective drugs against AD. DL-3-n-butylphthalide (NBP) is a compound extract
Autor:
Ling‐Zhi Xu, Bing‐Qiu Li, Fang‐Yu Li, Mei‐Na Quan, Wei Qin, Ying Li, Wen‐Wen Li, Yu Zhao, Yi‐Ping Wei, Jian‐Ping Jia
Publikováno v:
CNS Neuroscience & Therapeutics.
Autor:
Yana Pang, Wei Qin, Chaojun Kong, Wenwen Li, Yan Li, Haishan Jiao, Heng Zhang, Yan Wang, Longfei Jia, Bing-Qiu Li, Shiyuan Wang, Lingzhi Xu, Jianping Jia
Publikováno v:
Journal of Alzheimer's disease : JAD. 82(4)
Background: Dysfunction of microglia has been increasingly recognized as a causative factor in Alzheimer’s disease (AD); thus, developing medicines capable of restoring microglial functions is critically important and constitutes a promising therap
Publikováno v:
Journal of Alzheimer's disease : JAD. 82(3)
Background: Alterations in levels of peripheral insulin-like growth factor-1 (IGF-1) in Alzheimer’s disease (AD) have been reported in several studies, and results are inconsistent. Objective: We conducted a meta-analysis to investigate the relatio
Autor:
Meina Quan, Lina Zhao, Tingting Li, Yan Li, Longfei Jia, Bing-Qiu Li, Lingzhi Xu, Qi Wang, Hongmei Jin, Jianping Jia, Qiongqiong Qiu
Publikováno v:
Neurobiology of Aging. 85:155.e1-155.e4
Presenilin 1 (PSEN1), presenilin 2 (PSEN2), and amyloid precursor protein (APP) genes account for the majority of autosomal dominant Alzheimer's disease (AD), with PSEN1 being the most common. We screened these genes for mutations in a Chinese proban
Publikováno v:
Molecular neurobiology. 56(4)
Alzheimer's disease (AD) is the most common neurodegenerative disease and seriously damages the health of elderly population. Clinical drug research targeting at classic pathology hallmarks, such as amyloid-β (Aβ) and tau protein, failed to achieve